Key apoptotic pathways for heat-induced programmed germ cell death in the testis APS Hikim, Y Lue, CM Yamamoto, Y Vera, S Rodriguez, PH Yen, ... Endocrinology 144 (7), 3167-3175, 2003 | 283 | 2003 |
Spontaneous germ cell apoptosis in humans: evidence for ethnic differences in the susceptibility of germ cells to programmed cell death AP Sinha Hikim, C Wang, Y Lue, L Johnson, XH Wang, RS Swerdloff The Journal of Clinical Endocrinology & Metabolism 83 (1), 152-156, 1998 | 243 | 1998 |
Deciphering the pathways of germ cell apoptosis in the testis APS Hikim, Y Lue, M Diaz-Romero, PH Yen, C Wang, RS Swerdloff The Journal of steroid biochemistry and molecular biology 85 (2-5), 175-182, 2003 | 239 | 2003 |
Long‐term effects of triptolide on spermatogenesis, epididymal sperm function, and fertility in male rats PN Huynh, APS Hikim, C Wang, K Stefonovic, YH Lue, A Leung, ... Journal of Andrology 21 (5), 689-699, 2000 | 195 | 2000 |
Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure YH Lue, K Erkkila, PY Liu, K Ma, C Wang, AS Hikim, RS Swerdloff The American journal of pathology 170 (3), 899-908, 2007 | 186 | 2007 |
Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation AP Sinha Hikim, TB Rajavashisth, IS Hikim, Y Lue, JJ Bonavera, A Leung, ... Biology of reproduction 57 (5), 1193-1201, 1997 | 181 | 1997 |
Testicular heat exposure enhances the suppression of spermatogenesis by testosterone in rats: the “two-hit” approach to male contraceptive development Y Lue, AP Sinha Hikim, C Wang, M Im, A Leung, RS Swerdloff Endocrinology 141 (4), 1414-1424, 2000 | 167 | 2000 |
Redistribution of Bax is an early step in an apoptotic pathway leading to germ cell death in rats, triggered by mild testicular hyperthermia CM Yamamoto, AP Sinha Hikim, PN Huynh, B Shapiro, Y Lue, ... Biology of reproduction 63 (6), 1683-1690, 2000 | 164 | 2000 |
Triptolide: a potential male contraceptive Y Lue, APS Hikim, C Wang, A Leung, S Baravarian, V Reutrakul, ... Journal of andrology 19 (4), 479-486, 1998 | 161 | 1998 |
Functional role of inducible nitric oxide synthase in the induction of male germ cell apoptosis, regulation of sperm number, and determination of testes size: evidence from … Y Lue, AP Sinha Hikim, C Wang, A Leung, RS Swerdloff Endocrinology 144 (7), 3092-3100, 2003 | 144 | 2003 |
Transient scrotal hyperthermia and levonorgestrel enhance testosterone-induced spermatogenesis suppression in men through increased germ cell apoptosis C Wang, YG Cui, XH Wang, Y Jia, A Sinha Hikim, YH Lue, JS Tong, ... The Journal of Clinical Endocrinology & Metabolism 92 (8), 3292-3304, 2007 | 138 | 2007 |
Posttesticular antifertility action of triptolide in the male rat: evidence for severe impairment of cauda epididymal sperm ultrastructure APS HIKIM, YANHE LUE, C WANG, V REUTRAKUL, R SANGSUWAN, ... Journal of andrology 21 (3), 431-437, 2000 | 138 | 2000 |
Mild testicular hyperthermia induces profound transitional spermatogenic suppression through increased germ cell apoptosis in adult cynomolgus monkeys (Macaca fascicularis) YANHE LUE, BL Lasley, LS Laughlin, RS Swerdloff, APS Hikim, A Leung, ... Journal of andrology 23 (6), 799-805, 2002 | 135 | 2002 |
Mitochondria-dependent pathway is involved in heat-induced male germ cell death: lessons from mutant mice Y Vera, M Diaz-Romero, S Rodriguez, Y Lue, C Wang, RS Swerdloff, ... Biology of reproduction 70 (5), 1534-1540, 2004 | 132 | 2004 |
Dedifferentiation of adult monkey Sertoli cells through activation of extracellularly regulated kinase 1/2 induced by heat treatment XS Zhang, ZH Zhang, X Jin, P Wei, XQ Hu, M Chen, CL Lu, YH Lue, ... Endocrinology 147 (3), 1237-1245, 2006 | 103 | 2006 |
Involvement of p38 mitogen-activated protein kinase and inducible nitric oxide synthase in apoptotic signaling of murine and human male germ cells after hormone deprivation Y Vera, K Erkkilä, C Wang, C Nunez, S Kyttänen, Y Lue, L Dunkel, ... Molecular endocrinology 20 (7), 1597-1609, 2006 | 97 | 2006 |
XXY male mice: an experimental model for Klinefelter syndrome Y Lue, PN Rao, AP Sinha Hikim, M Im, WA Salameh, PH Yen, C Wang, ... Endocrinology 142 (4), 1461-1470, 2001 | 90 | 2001 |
Aggresome formation in liver cells in response to different toxic mechanisms: role of the ubiquitin-proteasome pathway and the frameshift mutant of ubiquitin BA French, F van Leeuwen, NE Riley, QX Yuan, F Bardag-Gorce, K Gaal, ... Experimental and molecular pathology 71 (3), 241-246, 2001 | 89 | 2001 |
Reproductive aging in the Brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement C WANG, APS HIKIM, YANHE LUE, A LEUNG, S BARAVARIAN, ... Journal of andrology 20 (4), 509-518, 1999 | 88 | 1999 |
The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan K Yen, HH Mehta, SJ Kim, YH Lue, J Hoang, N Guerrero, J Port, Q Bi, ... Aging (Albany NY) 12 (12), 11185, 2020 | 84 | 2020 |