STAT5 is a key regulator in NK cells and acts as a molecular switch from tumor surveillance to tumor promotion D Gotthardt, EM Putz, E Grundschober, M Prchal-Murphy, E Straka, ... Cancer Discovery 6 (4), 414-429, 2016 | 146 | 2016 |
Tyrosine kinase 2–Surveillant of tumours and bona fide oncogene NR Leitner, A Witalisz-Siepracka, B Strobl, M Mueller Cytokine 89, 209-218, 2017 | 50 | 2017 |
Loss of JAK1 drives innate immune deficiency A Witalisz-Siepracka, K Klein, D Prinz, N Leidenfrost, G Schabbauer, ... Frontiers in Immunology 9, 3108, 2019 | 48 | 2019 |
NK Cell–Specific CDK8 deletion enhances antitumor responses A Witalisz-Siepracka, D Gotthardt, M Prchal-Murphy, Z Didara, I Menzl, ... Cancer immunology research 6 (4), 458-466, 2018 | 46 | 2018 |
CDK8-novel therapeutic opportunities I Menzl, A Witalisz-Siepracka, V Sexl Pharmaceuticals 12 (2), 92, 2019 | 41 | 2019 |
Effect of heme oxygenase-1 on ochratoxin A-induced nephrotoxicity in mice A Loboda, A Stachurska, P Podkalicka, M Sobczak, O Mucha, ... The International Journal of Biochemistry & Cell Biology 84, 46-57, 2017 | 33 | 2017 |
In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity M Prchal-Murphy, A Witalisz-Siepracka, KT Bednarik, EM Putz, ... Oncoimmunology 4 (11), e1047579, 2015 | 30 | 2015 |
Human signal transducer and activator of transcription 5b (STAT5b) mutation causes dysregulated human natural killer cell maturation and impaired lytic function A Vargas-Hernández, A Witalisz-Siepracka, M Prchal-Murphy, K Klein, ... Journal of Allergy and Clinical Immunology 145 (1), 345-357. e9, 2020 | 24 | 2020 |
STAT1 isoforms differentially regulate NK cell maturation and anti-tumor activity K Meissl, N Simonović, L Amenitsch, A Witalisz-Siepracka, K Klein, ... Frontiers in immunology 11, 2189, 2020 | 19 | 2020 |
STAT5 is a key regulator in NK cells and acts as a molecular switch from tumor surveillance to tumor promotion. Cancer Discov. 2016; 6: 414–429. doi: 10.1158/2159-8290 D Gotthardt, EM Putz, E Grundschober, M Prchal-Murphy, E Straka, ... CD-15-0732.[Abstract][CrossRef][Google Scholar], 0 | 19 | |
The multifaceted role of STAT3 in NK-cell tumor surveillance A Witalisz-Siepracka, K Klein, B Zdársky, D Stoiber Frontiers in Immunology 13, 947568, 2022 | 18 | 2022 |
Untwining anti-tumor and immunosuppressive effects of JAK inhibitors—a strategy for hematological malignancies? K Klein, D Stoiber, V Sexl, A Witalisz-Siepracka Cancers 13 (11), 2611, 2021 | 17 | 2021 |
Triple-negative breast cancer cells rely on kinase-independent functions of CDK8 to evade NK-cell-mediated tumor surveillance VM Knab, D Gotthardt, K Klein, R Grausenburger, G Heller, I Menzl, ... Cell Death & Disease 12 (11), 991, 2021 | 16 | 2021 |
STAT5BN642H drives transformation of NKT cells: a novel mouse model for CD56+ T-LGL leukemia K Klein, A Witalisz-Siepracka, B Maurer, D Prinz, G Heller, N Leidenfrost, ... Leukemia 33 (9), 2336-2340, 2019 | 15 | 2019 |
The ups and downs of STAT inhibition in acute myeloid leukemia B Moser, S Edtmayer, A Witalisz-Siepracka, D Stoiber Biomedicines 9 (8), 1051, 2021 | 13 | 2021 |
NK cells require cell-extrinsic and-intrinsic TYK2 for full functionality in tumor surveillance and antibacterial immunity N Simonović, A Witalisz-Siepracka, K Meissl, C Lassnig, U Reichart, ... The Journal of Immunology 202 (6), 1724-1734, 2019 | 13 | 2019 |
Loss of NKG2D in murine NK cells leads to increased perforin production upon long‐term stimulation with IL‐2 D Prinz, K Klein, J List, VM Knab, I Menzl, N Leidenfrost, G Heller, B Polić, ... European journal of immunology 50 (6), 880-890, 2020 | 11 | 2020 |
T Cell-Intrinsic CDK6 Is Dispensable for Anti-Viral and Anti-Tumor Responses In Vivo K Klein, A Witalisz-Siepracka, D Gotthardt, B Agerer, F Locker, ... Frontiers in Immunology 12, 650977, 2021 | 7 | 2021 |
NK cell-specific CDK8 deletion enhances antitumor responses. Cancer Immunol. Res. 2018; 6: 458–466. doi: 10.1158/2326-6066 A Witalisz-Siepracka, D Gotthardt, M Prchal-Murphy, Z Didara, I Menzl, ... CIR-17-0183.[Abstract][CrossRef][Google Scholar], 0 | 6 | |
Human STAT5b mutation causes dysregulated human natural killer cell maturation and impaired lytic function. A Vargas-Hernández, A Witalisz-Siepracka, M Prchal-Murphy, K Klein, ... The Journal of allergy and clinical immunology 145 (1), 345, 2020 | 4 | 2020 |