Conserved and cooperative assembly of membrane-bound α-helical states of islet amyloid polypeptide JD Knight, JA Hebda, AD Miranker Biochemistry 45 (31), 9496-9508, 2006 | 383 | 2006 |
The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes JA Hebda, AD Miranker Annual review of biophysics 38 (1), 125-152, 2009 | 279 | 2009 |
Synthetic α-helix mimetics as agonists and antagonists of IAPP amyloid formation I Saraogi, JA Hebda, J Becerril, LA Estroff, AD Miranker, AD Hamilton Angewandte Chemie (International ed. in English) 49 (4), 736, 2010 | 149 | 2010 |
A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes JA Hebda, I Saraogi, M Magzoub, AD Hamilton, AD Miranker Chemistry & biology 16 (9), 943-950, 2009 | 111 | 2009 |
Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide BW Koo, JA Hebda, AD Miranker Protein Engineering, Design & Selection 21 (3), 147-154, 2008 | 68 | 2008 |
Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics S Kumar, DE Schlamadinger, MA Brown, JM Dunn, B Mercado, JA Hebda, ... Chemistry & biology 22 (3), 369-378, 2015 | 67 | 2015 |
Small molecule screening in context: Lipid‐catalyzed amyloid formation JA Hebda, M Magzoub, AD Miranker Protein Science 23 (10), 1341-1348, 2014 | 15 | 2014 |
Exploring biased probability using loaded dice: an active learning exercise with analogy to entropic and energetic determinants of equilibria in chemical systems JA Hebda, Z Aamold Journal of Chemical Education 96 (8), 1686-1690, 2019 | 5 | 2019 |
Inhibition and Mechanism of Islet Amyloid Polypeptide Toxicity DE Schlamadinger, S Kumar, M Magzoub, JA Hebda, AD Miranker Biophysical Journal 104 (2), 56a, 2013 | 1 | 2013 |
Determining the Evolutionary Significance of Palindromic Sequences in Proteins J Hebda, S Ahmad PROTEIN SCIENCE 30, 110-111, 2021 | | 2021 |
BIASING BINDING ORIENTATION OF THE C-TERMINAL STRAND EXCHANGE LIMITS CHAPERONE FUNCTION IN HUMAN ALPHA-B CRYSTALLIN J Hebda, D Draeger, K Nguyen, A Nevels PROTEIN SCIENCE 28, 184-185, 2019 | | 2019 |
Stability and Dynamics of Alpha Crystallin Oligomers Probed by FRET and FCS Reveal Persistent Oligomerization Under Dilute Conditions AH Pearlman, S Salvi, PB O'Hara, JA Hebda Biophysical Journal 106 (2), 247a, 2014 | | 2014 |
Clarifying the Intersection Between Alpha-Crystallin B Function and Oligomerization by Altering Aggregation Conditions R Cabrejo, J Hebda, PB O'Hara Biophysical Journal 106 (2), 471a, 2014 | | 2014 |
Characterizing the Role of Palindromic Strand Exchange in Alpha Crystallin Oligomerization JA Hebda, A Pearlman, PB O'Hara Biophysical Journal 104 (2), 394a, 2013 | | 2013 |
Clarifying Alpha Crystallin Chaperone Function by using an Insulin B-Chain Aggregation Model KW Cheng, RG Cabrejo, AH Pearlman, JA Hebda, PB O'Hara Biophysical Journal 104 (2), 48a, 2013 | | 2013 |
Elucidating Molecular Constraints that Effect Alpha Crystallin Oligomerization, Stability, and Chaperone Function J Santos, R Cabrejo, P O'Hara, J Hebda Biophysical Journal 102 (3), 60a, 2012 | | 2012 |
Agonist AMD Antagonist Activity in a GFP Yeast Based Estrogen Receptor Functional Assay J Watson, J Hebda, PB O'Hara Biophysical Journal 102 (3), 74a, 2012 | | 2012 |
Elucidating the Mechanism of Amyloid Assembly in Islet Amyloid Polypeptide Through Small Molecule Interference JA Hebda Yale University, 2011 | | 2011 |
Small Molecule Inhibitors of Islet Amyloid Polypeptide Fibrillogenesis and Cytotoxicity M Magzoub, JA Hebda, A Miranker Biophysical Journal 98 (3), 255a, 2010 | | 2010 |
1341 Small molecule screening in context: Lipid-catalyzed amyloid formation JA Hebda, M Magzoub, AD Miranker, Y Shi, A Abdolvahabi, BF Shaw | | |