关注
James A. Hebda
James A. Hebda
其他姓名James Alexander Hebda
Associate Professor of Biochemistry, Austin College
在 austincollege.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Conserved and cooperative assembly of membrane-bound α-helical states of islet amyloid polypeptide
JD Knight, JA Hebda, AD Miranker
Biochemistry 45 (31), 9496-9508, 2006
3832006
The interplay of catalysis and toxicity by amyloid intermediates on lipid bilayers: insights from type II diabetes
JA Hebda, AD Miranker
Annual review of biophysics 38 (1), 125-152, 2009
2792009
Synthetic α-helix mimetics as agonists and antagonists of IAPP amyloid formation
I Saraogi, JA Hebda, J Becerril, LA Estroff, AD Miranker, AD Hamilton
Angewandte Chemie (International ed. in English) 49 (4), 736, 2010
1492010
A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetes
JA Hebda, I Saraogi, M Magzoub, AD Hamilton, AD Miranker
Chemistry & biology 16 (9), 943-950, 2009
1112009
Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide
BW Koo, JA Hebda, AD Miranker
Protein Engineering, Design & Selection 21 (3), 147-154, 2008
682008
Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics
S Kumar, DE Schlamadinger, MA Brown, JM Dunn, B Mercado, JA Hebda, ...
Chemistry & biology 22 (3), 369-378, 2015
672015
Small molecule screening in context: Lipid‐catalyzed amyloid formation
JA Hebda, M Magzoub, AD Miranker
Protein Science 23 (10), 1341-1348, 2014
152014
Exploring biased probability using loaded dice: an active learning exercise with analogy to entropic and energetic determinants of equilibria in chemical systems
JA Hebda, Z Aamold
Journal of Chemical Education 96 (8), 1686-1690, 2019
52019
Inhibition and Mechanism of Islet Amyloid Polypeptide Toxicity
DE Schlamadinger, S Kumar, M Magzoub, JA Hebda, AD Miranker
Biophysical Journal 104 (2), 56a, 2013
12013
Determining the Evolutionary Significance of Palindromic Sequences in Proteins
J Hebda, S Ahmad
PROTEIN SCIENCE 30, 110-111, 2021
2021
BIASING BINDING ORIENTATION OF THE C-TERMINAL STRAND EXCHANGE LIMITS CHAPERONE FUNCTION IN HUMAN ALPHA-B CRYSTALLIN
J Hebda, D Draeger, K Nguyen, A Nevels
PROTEIN SCIENCE 28, 184-185, 2019
2019
Stability and Dynamics of Alpha Crystallin Oligomers Probed by FRET and FCS Reveal Persistent Oligomerization Under Dilute Conditions
AH Pearlman, S Salvi, PB O'Hara, JA Hebda
Biophysical Journal 106 (2), 247a, 2014
2014
Clarifying the Intersection Between Alpha-Crystallin B Function and Oligomerization by Altering Aggregation Conditions
R Cabrejo, J Hebda, PB O'Hara
Biophysical Journal 106 (2), 471a, 2014
2014
Characterizing the Role of Palindromic Strand Exchange in Alpha Crystallin Oligomerization
JA Hebda, A Pearlman, PB O'Hara
Biophysical Journal 104 (2), 394a, 2013
2013
Clarifying Alpha Crystallin Chaperone Function by using an Insulin B-Chain Aggregation Model
KW Cheng, RG Cabrejo, AH Pearlman, JA Hebda, PB O'Hara
Biophysical Journal 104 (2), 48a, 2013
2013
Elucidating Molecular Constraints that Effect Alpha Crystallin Oligomerization, Stability, and Chaperone Function
J Santos, R Cabrejo, P O'Hara, J Hebda
Biophysical Journal 102 (3), 60a, 2012
2012
Agonist AMD Antagonist Activity in a GFP Yeast Based Estrogen Receptor Functional Assay
J Watson, J Hebda, PB O'Hara
Biophysical Journal 102 (3), 74a, 2012
2012
Elucidating the Mechanism of Amyloid Assembly in Islet Amyloid Polypeptide Through Small Molecule Interference
JA Hebda
Yale University, 2011
2011
Small Molecule Inhibitors of Islet Amyloid Polypeptide Fibrillogenesis and Cytotoxicity
M Magzoub, JA Hebda, A Miranker
Biophysical Journal 98 (3), 255a, 2010
2010
1341 Small molecule screening in context: Lipid-catalyzed amyloid formation
JA Hebda, M Magzoub, AD Miranker, Y Shi, A Abdolvahabi, BF Shaw
系统目前无法执行此操作,请稍后再试。
文章 1–20