Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay. IG Bruno, R Karam, L Huang, A Bhardwaj, CH Lou, EY Shum, HW Song, ... Molecular cell 42 (4), 500, 2011 | 347 | 2011 |
PintlincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2 O Marín-Béjar, FP Marchese, A Athie, Y Sánchez, J González, V Segura, ... Genome biology 14, 1-17, 2013 | 270 | 2013 |
An alternative branch of the nonsense‐mediated decay pathway WK Chan, L Huang, JP Gudikote, YF Chang, JS Imam, JA MacLean, ... The EMBO journal 26 (7), 1820-1830, 2007 | 247 | 2007 |
RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD L Huang, CH Lou, W Chan, EY Shum, A Shao, E Stone, R Karam, ... Molecular Cell 43 (6), 950-961, 2011 | 233 | 2011 |
Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway CH Lou, A Shao, EY Shum, JL Espinoza, L Huang, R Karam, ... Cell reports 6 (4), 748-764, 2014 | 177 | 2014 |
The antagonistic gene paralogs Upf3a and Upf3b govern nonsense-mediated RNA decay EY Shum, SH Jones, A Shao, JN Chousal, MD Krause, WK Chan, CH Lou, ... Cell 165 (2), 382-395, 2016 | 155 | 2016 |
A UPF3-mediated regulatory switch that maintains RNA surveillance WK Chan, AD Bhalla, H Le Hir, LS Nguyen, L Huang, J Gécz, ... Nature Structural & Molecular Biology 16 (7), 747-753, 2009 | 143 | 2009 |
Regulation of nonsense‐mediated mRNA decay L Huang, MF Wilkinson Wiley Interdisciplinary Reviews: RNA 3 (6), 807-828, 2012 | 136 | 2012 |
Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability LS Nguyen, L Jolly, C Shoubridge, WK Chan, L Huang, F Laumonnier, ... Molecular Psychiatry, 2011 | 124 | 2011 |
The unfolded protein response is shaped by the NMD pathway R Karam, CH Lou, H Kroeger, L Huang, JH Lin, MF Wilkinson EMBO reports 16 (5), 599-609, 2015 | 123 | 2015 |
Antifungal and new metabolites of Myrothecium sp. Z16, a fungus associated with white croaker Argyrosomus argentatus JY Liu, LL Huang, YH Ye, WX Zou, ZJ Guo, RX Tan Journal of Applied Microbiology 100 (1), 195-202, 2006 | 75 | 2006 |
A Upf3b-mutant mouse model with behavioral and neurogenesis defects L Huang, EY Shum, SH Jones, CH Lou, J Chousal, H Kim, AJ Roberts, ... Molecular psychiatry 23 (8), 1773-1786, 2018 | 67 | 2018 |
Nonsense-mediated RNA decay pathway inhibition restores expression and function of W1282X CFTR MM Keenan, L Huang, NJ Jordan, E Wong, Y Cheng, HC Valley, ... American journal of respiratory cell and molecular biology 61 (3), 290-300, 2019 | 63 | 2019 |
New approaches to genetic therapies for cystic fibrosis AC Boyd, S Guo, L Huang, B Kerem, YS Oren, AJ Walker, SL Hart Journal of Cystic Fibrosis 19, S54-S59, 2020 | 58 | 2020 |
Antifungal metabolite with a new carbon skeleton from Keissleriella sp. YS4108, a marine filamentous fungus CH Liu, JC Meng, WX Zou, LL Huang, HQ Tang, RX Tan Planta medica 68 (04), 363-365, 2002 | 53 | 2002 |
Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations L Huang, A Low, SS Damle, MM Keenan, S Kuntz, SF Murray, BP Monia, ... Genome biology 19, 1-16, 2018 | 52 | 2018 |
Knockdown of nuclear-retained long noncoding RNAs using modified DNA antisense oligonucleotides X Zong, L Huang, V Tripathi, R Peralta, SM Freier, S Guo, KV Prasanth Nuclear Bodies and Noncoding RNAs: Methods and Protocols, 321-331, 2015 | 36 | 2015 |
Targeting translation termination machinery with antisense oligonucleotides for diseases caused by nonsense mutations L Huang, M Aghajan, T Quesenberry, A Low, SF Murray, BP Monia, S Guo nucleic acid therapeutics 29 (4), 175-186, 2019 | 29 | 2019 |
Partial hepatectomy induced long noncoding RNA inhibits hepatocyte proliferation during liver regeneration L Huang, SS Damle, S Booten, P Singh, M Sabripour, J Hsu, M Jo, M Katz, ... PLoS One 10 (7), e0132798, 2015 | 28 | 2015 |
Absolute configuration of keisslone, a new antimicrobial metabolite from Keissleriella sp. YS4108, a marine filamentous fungus CH Liu, JY Liu, LL Huang, WX Zou, RX Tan Planta medica 69 (05), 481-483, 2003 | 28 | 2003 |