Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment C Falcomata, S Baerthel, SA Widholz, C Schneeweis, JJ Montero, ... Nature Cancer 3 (3), 318-336, 2022 | 60 | 2022 |
Context-specific determinants of the immunosuppressive tumor microenvironment in pancreatic cancer C Falcomatà, S Bärthel, G Schneider, R Rad, M Schmidt-Supprian, ... Cancer Discovery 13 (2), 278-297, 2023 | 51 | 2023 |
Mass spectrometry-based draft of the mouse proteome P Giansanti, P Samaras, Y Bian, C Meng, A Coluccio, M Frejno, ... Nature methods 19 (7), 803-811, 2022 | 32 | 2022 |
Single-cell profiling to explore pancreatic cancer heterogeneity, plasticity and response to therapy S Bärthel, C Falcomatà, R Rad, FJ Theis, D Saur Nature cancer 4 (4), 454-467, 2023 | 28 | 2023 |
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver T Kaltenbacher, J Löprich, R Maresch, J Weber, S Müller, R Oellinger, ... Nature Protocols 17 (4), 1142-1188, 2022 | 18 | 2022 |
Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer C Falcomatà, S Bärthel, A Ulrich, S Diersch, C Veltkamp, L Rad, F Boniolo, ... Cancer discovery 11 (12), 3158-3177, 2021 | 16 | 2021 |
Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation JJ Swietlik, S Bärthel, C Falcomatà, D Fink, A Sinha, J Cheng, S Ebner, ... Nature Communications 14 (1), 2642, 2023 | 7 | 2023 |
Blocking the road to de‐differentiation: HNF 1A/KDM 6A complex safeguards epithelial integrity in pancreatic cancer S Bärthel, G Schneider, D Saur The EMBO Journal 39 (9), e104759, 2020 | 5 | 2020 |
ZEB1-dependent modulation of fibroblast polarization governs inflammation and immune checkpoint blockade sensitivity in colorectal cancer H Schuhwerk, C Menche, I Armstark, P Gupta, K Fuchs, R van Roey, ... bioRxiv, 2023.03. 28.534565, 2023 | 3 | 2023 |
Deciphering the universe of genetic context-dependencies using mouse models of cancer C Falcomatà, S Bärthel, G Schneider, D Saur, C Veltkamp Current Opinion in Genetics & Development 54, 97-104, 2019 | 3 | 2019 |
Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion X Wang, R Istvanffy, L Ye, S Teller, M Laschinger, KN Diakopoulos, ... The Journal of Clinical Investigation 133 (21), 2023 | 2 | 2023 |
Mitochondrial perturbation of the epithelium causes microbial dysbiosis and unresolved tissue injury in intestinal inflammation E Urbauer, D Aguanno, N Mindermann, H Omer, A Metwaly, S Khaloian, ... | 1 | 2023 |
ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer C Menche, H Schuhwerk, I Armstark, P Gupta, K Fuchs, R van Roey, ... EMBO reports, 1-26, 2024 | | 2024 |
Multimodal spatial transcriptomics uncover distinct tumor microenvironment states and cell-cell communication networks in molecular pancreatic cancer subtypes S Baerthel, C Falcomatà, V Goelling, D Lucarelli, R Gindra, C Schmitt, ... Cancer Research 84 (6_Supplement), 1587-1587, 2024 | | 2024 |
An in ovo model to study tumour morphogenesis and metastatic dissemination of PDAC R Ranjan, A Ravichandra, P Heuschneider, S Bärthel, K Steiger, ... Pancreatology 23, e136, 2023 | | 2023 |
Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease E Urbauer, D Aguanno, N Mindermann, H Omer, A Metwaly, T Krammel, ... bioRxiv, 2023.07. 27.549844, 2023 | | 2023 |
Syngeneic Mouse Orthotopic Allografts to Model Pancreatic Cancer C Schmitt, D Saur, S Baerthel, C Falcomata JoVE (Journal of Visualized Experiments), e64253, 2022 | | 2022 |
Characterization of the tumor microenvironment and cell-cell communication networks in pancreatic cancer subtypes S Bärthel Technische Universität München, 2022 | | 2022 |