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Bruce J. Wittmann
Bruce J. Wittmann
Senior Applied Scientist, Microsoft Office of the Chief Scientific Officer
在 microsoft.com 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Machine learning-assisted directed protein evolution with combinatorial libraries
Z Wu, SBJ Kan, RD Lewis, BJ Wittmann, FH Arnold
Proceedings of the National Academy of Sciences 116 (18), 8852-8858, 2019
5602019
Informed training set design enables efficient machine learning-assisted directed protein evolution
BJ Wittmann, Y Yue, FH Arnold
Cell systems 12 (11), 1026-1045. e7, 2021
1682021
Advances in machine learning for directed evolution
BJ Wittmann, KE Johnston, Z Wu, FH Arnold
Current opinion in structural biology 69, 11-18, 2021
1422021
FLIP: Benchmark tasks in fitness landscape inference for proteins
C Dallago, J Mou, KE Johnston, BJ Wittmann, N Bhattacharya, S Goldman, ...
bioRxiv, 2021.11. 09.467890, 2021
1092021
Diversity-oriented enzymatic synthesis of cyclopropane building blocks
BJ Wittmann, AM Knight, JL Hofstra, SE Reisman, SB Jennifer Kan, ...
ACS catalysis 10 (13), 7112-7116, 2020
552020
EvSeq: cost-effective amplicon sequencing of every variant in a protein library
BJ Wittmann, KE Johnston, PJ Almhjell, FH Arnold
ACS Synthetic Biology 11 (3), 1313-1324, 2022
392022
Flip: Benchmark tasks in fitness landscape inference for proteins. bioRxiv
C Dallago, J Mou, KE Johnston, BJ Wittmann, N Bhattacharya, S Goldman, ...
preprint, 2021
242021
Transcriptomic analysis illuminates genes involved in chlorophyll synthesis after nitrogen starvation in Acaryochloris sp. CCMEE 5410
A Yoneda, BJ Wittmann, JD King, RE Blankenship, G Dantas
Photosynthesis research 129, 171-182, 2016
232016
Machine learning-assisted directed evolution navigates a combinatorial epistatic fitness landscape with minimal screening burden
BJ Wittmann, Y Yue, FH Arnold
Biorxiv, 2020.12. 04.408955, 2020
182020
Machine learning for protein engineering
KE Johnston, C Fannjiang, BJ Wittmann, BL Hie, KK Yang, Z Wu
Machine Learning in Molecular Sciences, 277-311, 2023
112023
Multistate and functional protein design using RoseTTAFold sequence space diffusion
SL Lisanza, JM Gershon, SWK Tipps, JN Sims, L Arnoldt, SJ Hendel, ...
Nature biotechnology, 1-11, 2024
72024
CARE: a Benchmark Suite for the Classification and Retrieval of Enzymes
J Yang, A Mora, S Liu, BJ Wittmann, A Anandkumar, FH Arnold, Y Yue
arXiv preprint arXiv:2406.15669, 2024
52024
Toward AI-Resilient Screening of Nucleic Acid Synthesis Orders: Process, Results, and Recommendations
BJ Wittmann, T Alexanian, C Bartling, J Beal, A Clore, J Diggans, ...
bioRxiv, 2024.12. 02.626439, 2024
2024
Strategies and Tools for Machine Learning-Assisted Protein Engineering
BJ Wittmann
California Institute of Technology, 2022
2022
Oligo Design
BJ Wittmann, KE Johnston, PJ Almhjell, FH Arnolda
Machine Learning for Improved Directed Evolution Efficiency and Outcome
BJ Wittmann, Z Wu, F Arnold
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