关注
Christopher L. Burcham
Christopher L. Burcham
Executive Director – Engineering, Eli Lilly and Company
在 lilly.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Kilogram-scale prexasertib monolactate monohydrate synthesis under continuous-flow CGMP conditions
KP Cole, JMC Groh, MD Johnson, CL Burcham, BM Campbell, ...
Science 356 (6343), 1144-1150, 2017
2692017
Continuous manufacturing in pharmaceutical process development and manufacturing
CL Burcham, AJ Florence, MD Johnson
Annual review of chemical and biomolecular engineering 9 (1), 253-281, 2018
1462018
Regions of attainable particle sizes in continuous and batch crystallization processes
T Vetter, CL Burcham, MF Doherty
Chemical Engineering Science 106, 167-180, 2014
1312014
Formulation and analytical development for low-dose oral drug products
J Zheng
John Wiley & Sons, 2009
1122009
The electrohydrodynamic stability of a liquid bridge: microgravity experiments on a bridge suspended in a dielectric gas
CL Burcham, DA Saville
Journal of Fluid Mechanics 405, 37-56, 2000
762000
Process intensification through continuous spherical crystallization using an oscillatory flow baffled crystallizer
R Peña, JA Oliva, CL Burcham, DJ Jarmer, ZK Nagy
Crystal Growth & Design 17 (9), 4776-4784, 2017
682017
Electrohydrodynamic stability: Taylor–Melcher theory for a liquid bridge suspended in a dielectric gas
CL Burcham, DA Saville
Journal of Fluid Mechanics 452, 163-187, 2002
642002
Pilot-scale continuous production of LY2886721: amide formation and reactive crystallization
CS Polster, KP Cole, CL Burcham, BM Campbell, AL Frederick, ...
Organic Process Research & Development 18 (11), 1295-1309, 2014
532014
Particle engineering: a strategy for establishing drug substance physical property specifications during small molecule development
RG Iacocca, CL Burcham, LR Hilden
Journal of pharmaceutical sciences 99 (1), 51-75, 2010
512010
Modeling and optimization of spherical agglomeration in suspension through a coupled population balance model
R Peña, CL Burcham, DJ Jarmer, D Ramkrishna, ZK Nagy
Chemical Engineering Science 167, 66-77, 2017
502017
Separation of conglomerate forming enantiomers using a novel continuous preferential crystallization process
T Vetter, CL Burcham, MF Doherty
AIChE Journal 61 (9), 2810-2823, 2015
482015
Further understanding of agglomeration mechanisms in spherical crystallization systems: benzoic acid case study
R Peña, DJ Jarmer, CL Burcham, ZK Nagy
Crystal Growth & Design 19 (3), 1668-1679, 2019
402019
Designing robust crystallization processes in the presence of parameter uncertainty using attainable regions
T Vetter, CL Burcham, MF Doherty
Industrial & Engineering Chemistry Research 54 (42), 10350-10363, 2015
342015
Quantitative measurements of internal circulation in droplets using flow tagging velocimetry
SR Harris, WR Lempert, L Hersh, CL Burcham, DA Saville, RB Miles, ...
AIAA journal 34 (3), 449-454, 1996
281996
A mechanistic model to predict droplet drying history and particle shell formation in multicomponent systems
H Abdullahi, CL Burcham, T Vetter
Chemical Engineering Science 224, 115713, 2020
272020
A continuous multi-stage mixed-suspension mixed-product-removal crystallization system with fines dissolution
D Acevedo, DJ Jarmer, CL Burcham, CS Polster, ZK Nagy
Chemical Engineering Research and Design 135, 112-120, 2018
272018
API continuous cooling and antisolvent crystallization for kinetic impurity rejection in cGMP manufacturing
MD Johnson, CL Burcham, SA May, JR Calvin, J McClary Groh, SS Myers, ...
Organic Process Research & Development 25 (6), 1284-1351, 2021
242021
Chapter 7; Using quality by design principles as a guide for designing a process control strategy
CL Burcham, M LaPack, JR Martinelli, N McCracken
Comprehensive Quality by Design for Pharmaceutical Product Development and …, 2017
21*2017
Iterative model‐based experimental design for spherical agglomeration processes
K Pal, B Szilagyi, CL Burcham, DJ Jarmer, ZK Nagy
AIChE Journal 67 (5), e17178, 2021
132021
Characterizing the impact of spray dried particle morphology on tablet dissolution using quantitative X-ray microscopy
S Zhang, PA Stroud, A Zhu, MJ Johnson, J Lomeo, CL Burcham, J Hinds, ...
European Journal of Pharmaceutical Sciences 165, 105921, 2021
122021
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