| Nitromethane as a nitrogen donor in Schmidt-type formation of amides and nitriles J Liu, C Zhang, Z Zhang, X Wen, X Dou, J Wei, X Qiu, S Song, N Jiao Science 367 (6475), 281-285, 2020 | 102 | 2020 |
| Catalytic electrophilic halogenation of arenes with electron-withdrawing substituents W Wang, X Yang, R Dai, Z Yan, J Wei, X Dou, X Qiu, H Zhang, C Wang, ... Journal of the American Chemical Society 144 (29), 13415-13425, 2022 | 69 | 2022 |
| Multistage screening reveals 3-substituted indolin-2-one derivatives as novel and isoform-selective c-Jun N-terminal kinase 3 (JNK3) inhibitors: implications to drug discovery … X Dou, H Huang, Y Li, L Jiang, Y Wang, H Jin, N Jiao, L Zhang, L Zhang, ... Journal of Medicinal Chemistry 62 (14), 6645-6664, 2019 | 46 | 2019 |
| Discovery of novel glycogen synthase kinase-3α inhibitors: Structure-based virtual screening, preliminary SAR and biological evaluation for treatment of acute myeloid leukemia Y Wang, X Dou, L Jiang, H Jin, L Zhang, L Zhang, Z Liu European Journal of Medicinal Chemistry 171, 221-234, 2019 | 24 | 2019 |
| Rational modification, synthesis and biological evaluation of 3, 4-dihydroquinoxalin-2 (1H)-one derivatives as potent and selective c-Jun N-terminal kinase 3 (JNK3) inhibitors X Dou, H Huang, L Jiang, G Zhu, H Jin, N Jiao, L Zhang, Z Liu, L Zhang European Journal of Medicinal Chemistry 201, 112445, 2020 | 23 | 2020 |
| Discovery of new GSK-3β inhibitors through structure-based virtual screening X Dou, L Jiang, Y Wang, H Jin, Z Liu, L Zhang Bioorganic & medicinal chemistry letters 28 (2), 160-166, 2018 | 23 | 2018 |
| Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing T Huo, X Zhao, Z Cheng, J Wei, M Zhu, X Dou, N Jiao Acta Pharmaceutica Sinica B, 2023 | 12 | 2023 |
| Discovery of 2-(furan-2-ylmethylene) hydrazine-1-carbothioamide derivatives as novel inhibitors of SARS-CoV-2 main protease X Dou, Q Sun, G Xu, Y Liu, C Zhang, B Wang, Y Lu, Z Guo, L Su, T Huo, ... European Journal of Medicinal Chemistry 238, 114508, 2022 | 11 | 2022 |
| Unravel a neuroactive sHA sulfation pattern with neurogenesis activity by a library of defined oligosaccharides W Yao, M Chen, X Dou, H Jin, X Zhang, Y Zhu, M Sha, Z Liu, X Meng, ... European journal of medicinal chemistry 163, 583-596, 2019 | 10 | 2019 |
| Functional screening and rational design of compounds targeting GPR132 to treat diabetes JL Wang, XD Dou, J Cheng, MX Gao, GF Xu, W Ding, JH Ding, Y Li, ... Nature Metabolism 5 (10), 1726-1746, 2023 | 8 | 2023 |
| Discovery of novel ataxia telangiectasia mutated (ATM) kinase modulators: computational simulation, biological evaluation and cancer combinational chemotherapy study X Dou, X Sun, H Huang, L Jiang, Z Jin, Y Liu, Y Zou, Z Li, G Zhu, H Jin, ... European Journal of Medicinal Chemistry 233, 114196, 2022 | 7 | 2022 |
| The structure-based optimization of 3-substituted indolin-2-one derivatives as potent and isoform-selective c-Jun N-terminal kinase 3 (JNK3) inhibitors and biological evaluation Z Li, G Zhu, X Liu, T Gao, F Fang, X Dou, Y Li, R Zheng, H Jin, L Zhang, ... European Journal of Medicinal Chemistry 250, 115167, 2023 | 5 | 2023 |
| Similar pyridinone compounds with different activities of anti-HIV-1 reverse transcriptase Y Liu, X Li, X Dou, C Tian, Z Zhang, J Liu, X Wang Journal of Chinese Pharmaceutical Sciences 27 (7), 2018 | 1 | 2018 |
| Fxr regulator, preparation method therefor, pharmaceutical composition thereof and use thereof N Jiao, X Dou, HUO Tongyu, SU Lingyu, Z Xinyi, Y Huang, Y Liu US Patent App. 18/555,470, 2024 | | 2024 |
| Discovery of novel and selective farnesoid X receptor antagonists through structure-based virtual screening, preliminary structure-activity relationship study, and biological … X Dou, T Huo, Y Liu, Z Pang, L Su, X Zhao, X Peng, Z Liu, L Zhang, N Jiao European Journal of Medicinal Chemistry 269, 116323, 2024 | | 2024 |
| Discovery of 3-oxo-1, 2, 3, 4-tetrahydropyrido [1, 2-a] pyrazin derivatives as SARS-CoV-2 main protease inhibitors through virtual screening and biological evaluation X Dou, Q Sun, Y Liu, Y Lu, C Zhang, G Xu, Y Xu, T Huo, X Zhao, L Su, ... Bioorganic & Medicinal Chemistry Letters 97, 129547, 2024 | | 2024 |
