| Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ... Cancer cell 24 (5), 660-672, 2013 | 758 | 2013 |
| A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity J Yang, W Wang, Z Chen, S Lu, F Yang, Z Bi, L Bao, F Mo, X Li, Y Huang, ... Nature 586 (7830), 572-577, 2020 | 744 | 2020 |
| Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ... Nature 511 (7510), 428-434, 2014 | 681 | 2014 |
| Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism Z Hu, D Zhu, W Wang, W Li, W Jia, X Zeng, W Ding, L Yu, X Wang, ... Nature genetics 47 (2), 158-163, 2015 | 510 | 2015 |
| BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ... Nature medicine 19 (7), 901-908, 2013 | 475 | 2013 |
| Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing V Hovestadt, DTW Jones, S Picelli, W Wang, M Kool, PA Northcott, ... Nature 510 (7506), 537-541, 2014 | 439 | 2014 |
| BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation S Raffel, M Falcone, N Kneisel, J Hansson, W Wang, C Lutz, L Bullinger, ... Nature 551 (7680), 384-388, 2017 | 325 | 2017 |
| Inducing and exploiting vulnerabilities for the treatment of liver cancer C Wang, S Vegna, H Jin, B Benedict, C Lieftink, C Ramirez, ... Nature 574 (7777), 268-272, 2019 | 317 | 2019 |
| Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing A Paruzynski, A Arens, R Gabriel, CC Bartholomae, S Scholz, W Wang, ... Nature protocols 5 (8), 1379-1395, 2010 | 230 | 2010 |
| Comprehensive genomic access to vector integration in clinical gene therapy R Gabriel, R Eckenberg, A Paruzynski, CC Bartholomae, A Nowrouzi, ... Nature medicine 15 (12), 1431-1436, 2009 | 221 | 2009 |
| Impaired meningeal lymphatic drainage in patients with idiopathic Parkinson’s disease XB Ding, XX Wang, DH Xia, H Liu, HY Tian, Y Fu, YK Chen, C Qin, ... Nature medicine 27 (3), 411-418, 2021 | 205 | 2021 |
| Tagmentation-based whole-genome bisulfite sequencing Q Wang, L Gu, A Adey, B Radlwimmer, W Wang, V Hovestadt, M Bähr, ... Nature protocols 8 (10), 2022-2032, 2013 | 180 | 2013 |
| Defect engineering enables synergistic action of enzyme-mimicking active centers for high-efficiency tumor therapy B Yu, W Wang, W Sun, C Jiang, L Lu Journal of the American Chemical Society 143 (23), 8855-8865, 2021 | 162 | 2021 |
| Hepatocyte‐targeted expression by integrase‐defective lentiviral vectors induces antigen‐specific tolerance in mice with low genotoxic risk J Mátrai, A Cantore, CC Bartholomae, A Annoni, W Wang, ... Hepatology 53 (5), 1696-1707, 2011 | 156 | 2011 |
| A pharmacogenomic landscape in human liver cancers Z Qiu, H Li, Z Zhang, Z Zhu, S He, X Wang, P Wang, J Qin, L Zhuang, ... Cancer Cell 36 (2), 179-193. e11, 2019 | 155 | 2019 |
| DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control H Kretzmer, SH Bernhart, W Wang, A Haake, MA Weniger, AK Bergmann, ... Nature genetics 47 (11), 1316-1325, 2015 | 144 | 2015 |
| Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia P Rio, S Navarro, W Wang, R Sanchez-Dominguez, RM Pujol, ... Nature medicine 25 (9), 1396-1401, 2019 | 143 | 2019 |
| Extensive methylation of promoter sequences silences lentiviral transgene expression during stem cell differentiation in vivo F Herbst, CR Ball, F Tuorto, A Nowrouzi, W Wang, O Zavidij, SM Dieter, ... Molecular Therapy 20 (5), 1014-1021, 2012 | 137 | 2012 |
| Loss of SATB1 induces p21-dependent cellular senescence in post-mitotic dopaminergic neurons M Riessland, B Kolisnyk, TW Kim, J Cheng, J Ni, JA Pearson, EJ Park, ... Cell stem cell 25 (4), 514-530. e8, 2019 | 125 | 2019 |
| Regenerative metaplastic clones in COPD lung drive inflammation and fibrosis W Rao, S Wang, M Duleba, S Niroula, K Goller, J Xie, R Mahalingam, ... Cell 181 (4), 848-864. e18, 2020 | 115 | 2020 |
