| Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice S Tanaka, H Hikita, T Tatsumi, R Sakamori, Y Nozaki, S Sakane, Y Shiode, ... Hepatology 64 (6), 1994-2014, 2016 | 311 | 2016 |
| Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations S Affo, A Nair, F Brundu, A Ravichandra, S Bhattacharjee, M Matsuda, ... Cancer cell 39 (6), 866-882. e11, 2021 | 229 | 2021 |
| Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandra, ... Nature 610 (7931), 356-365, 2022 | 129 | 2022 |
| DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway Y Saito, H Hikita, Y Nozaki, Y Kai, Y Makino, T Nakabori, S Tanaka, ... Cell Death & Differentiation 26 (3), 470-486, 2019 | 52 | 2019 |
| Signal transducer and activator of transcription 5 plays a crucial role in hepatic lipid metabolism through regulation of CD36 expression A Hosui, T Tatsumi, H Hikita, Y Saito, N Hiramatsu, M Tsujii, ... Hepatology Research 47 (8), 813-825, 2017 | 40 | 2017 |
| Activation of the mitochondrial apoptotic pathway produces reactive oxygen species and oxidative damage in hepatocytes that contribute to liver tumorigenesis H Hikita, T Kodama, S Tanaka, Y Saito, Y Nozaki, T Nakabori, S Shimizu, ... Cancer prevention research 8 (8), 693-701, 2015 | 31 | 2015 |
| S100A8 production in CXCR2-expressing CD11b+ Gr-1high cells aggravates hepatitis in mice fed a high-fat and high-cholesterol diet K Mukai, T Miyagi, K Nishio, Y Yokoyama, T Yoshioka, Y Saito, S Tanaka, ... The Journal of Immunology 196 (1), 395-406, 2016 | 30 | 2016 |
| TAZ-induced Cybb contributes to liver tumor formation in non-alcoholic steatohepatitis X Wang, S Zeldin, H Shi, C Zhu, Y Saito, KE Corey, SA Osganian, ... Journal of hepatology 76 (4), 910-920, 2022 | 28 | 2022 |
| Sodium taurocholate cotransporting polypeptide inhibition efficiently blocks hepatitis B virus spread in mice with a humanized liver T Nakabori, H Hikita, K Murai, Y Nozaki, Y Kai, Y Makino, Y Saito, ... Scientific reports 6 (1), 27782, 2016 | 26 | 2016 |
| A therapeutically targetable TAZ-TEAD2 pathway drives the growth of hepatocellular carcinoma via ANLN and KIF23 Y Saito, D Yin, N Kubota, X Wang, A Filliol, H Remotti, A Nair, L Fazlollahi, ... Gastroenterology 164 (7), 1279-1292, 2023 | 16 | 2023 |
| The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver T Kodama, H Hikita, T Kawaguchi, Y Saito, S Tanaka, M Shigekawa, ... Journal of Biological Chemistry 288 (42), 30009-30018, 2013 | 14 | 2013 |
| Combinations of two drugs among NS3/4A inhibitors, NS5B inhibitors and non-selective antiviral agents are effective for hepatitis C virus with NS5A-P32 deletion in humanized … A Doi, H Hikita, Y Kai, Y Tahata, Y Saito, T Nakabori, R Yamada, ... Journal of Gastroenterology 54, 449-458, 2019 | 6 | 2019 |
| Gab1 in livers with persistent hepatocyte apoptosis has an antiapoptotic effect and reduces chronic liver injury, fibrosis, and tumorigenesis N Mizutani, H Hikita, Y Saito, Y Myojin, K Sato, M Urabe, T Kurahashi, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 320 (6 …, 2021 | 5 | 2021 |
| Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver … Y Nozaki, H Hikita, S Tanaka, K Fukumoto, M Urabe, K Sato, Y Myojin, ... Scientific Reports 11 (1), 3363, 2021 | 5 | 2021 |
| Activation of p53 after irradiation impairs the regenerative capacity of the mouse liver M Urabe, H Hikita, Y Saito, S Kudo, K Fukumoto, N Mizutani, Y Myojin, ... Hepatology Communications 6 (2), 411-422, 2022 | 2 | 2022 |
| Esophageal pyogenic granuloma developed after short‐term follow‐up Y Saito, T Nishida, M Kato, T Inoue, S Yamamoto, Y Hayashi, T Akasaka, ... Diseases of the Esophagus 26 (3), 343-344, 2013 | 2 | 2013 |
