关注
Nicholas Yoder
Nicholas Yoder
未知所在单位机构
在 immunogen.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Fluorinated amino acids in protein design and engineering
NC Yoder, K Kumar
Chemical Society Reviews 31 (6), 335-341, 2002
3732002
Site-specific N-and C-terminal labeling of a single polypeptide using sortases of different specificity
JM Antos, GL Chew, CP Guimaraes, NC Yoder, GM Grotenbreg, ...
Journal of the American Chemical Society 131 (31), 10800-10801, 2009
2972009
Effects of drug–antibody ratio on pharmacokinetics, biodistribution, efficacy, and tolerability of antibody–maytansinoid conjugates
X Sun, JF Ponte, NC Yoder, R Laleau, J Coccia, L Lanieri, Q Qiu, R Wu, ...
Bioconjugate Chemistry 28 (5), 1371-1381, 2017
2232017
Preparation of unnatural N-to-N and C-to-C protein fusions
MD Witte, JJ Cragnolini, SK Dougan, NC Yoder, MW Popp, HL Ploegh
Proceedings of the National Academy of Sciences 109 (30), 11993-11998, 2012
1552012
A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells
Y Kovtun, GE Jones, S Adams, L Harvey, CA Audette, A Wilhelm, C Bai, ...
Blood advances 2 (8), 848-858, 2018
1542018
Understanding how the stability of the thiol-maleimide linkage impacts the pharmacokinetics of lysine-linked antibody–maytansinoid conjugates
JF Ponte, X Sun, NC Yoder, N Fishkin, R Laleau, J Coccia, L Lanieri, ...
Bioconjugate chemistry 27 (7), 1588-1598, 2016
902016
Bioorthogonal noncovalent chemistry: fluorous phases in chemical biology
NC Yoder, D Yüksel, L Dafik, K Kumar
Current opinion in chemical biology 10 (6), 576-583, 2006
692006
The chlamydial OTU domain‐containing protein ChlaOTU is an early type III secretion effector targeting ubiquitin and NDP52
AR Furtado, M Essid, S Perrinet, ME Balañá, N Yoder, P Dehoux, A Subtil
Cellular Microbiology 15 (12), 2064-2079, 2013
552013
A DNA-interacting payload designed to eliminate cross-linking improves the therapeutic index of antibody–drug conjugates (ADCs)
ML Miller, M Shizuka, A Wilhelm, P Salomon, EE Reid, L Lanieri, S Sikka, ...
Molecular Cancer Therapeutics 17 (3), 650-660, 2018
522018
Discovery and optimization of HKT288, a Cadherin-6–Targeting ADC for the treatment of ovarian and renal cancers
CU Bialucha, SD Collins, X Li, P Saxena, X Zhang, C Dürr, B Lafont, ...
Cancer discovery 7 (9), 1030-1045, 2017
492017
Catch‐and‐Release Probes Applied to Semi‐Intact Cells Reveal Ubiquitin‐Specific Protease Expression in Chlamydia trachomatis Infection
JHL Claessen, MD Witte, NC Yoder, AY Zhu, E Spooner, HL Ploegh
Chembiochem 14 (3), 343-352, 2013
462013
Using sortases to install click chemistry handles for protein ligation
HL Ploegh, MD Witte, NC Yoder
US Patent 10,081,684, 2018
452018
Structure and thermotropic phase behavior of fluorinated phospholipid bilayers: a combined attenuated total reflection FTIR spectroscopy and imaging ellipsometry study
S Schuy, S Faiss, NC Yoder, V Kalsani, K Kumar, A Janshoff, R Vogel
The Journal of Physical Chemistry B 112 (28), 8250-8256, 2008
412008
Nanoscale Patterning in Mixed Fluorocarbon− Hydrocarbon Phospholipid Bilayers
NC Yoder, V Kalsani, S Schuy, R Vogel, A Janshoff, K Kumar
Journal of the American Chemical Society 129 (29), 9037-9043, 2007
412007
Use of fungal derived polysaccharide-conjugated particles to probe Dectin-1 responses in innate immunity
JM Tam, MK Mansour, NS Khan, NC Yoder, JM Vyas
Integrative Biology 4 (2), 220-227, 2012
402012
A case study comparing heterogeneous lysine-and site-specific cysteine-conjugated maytansinoid antibody-drug conjugates (ADCs) illustrates the benefits of lysine conjugation
NC Yoder, C Bai, D Tavares, WC Widdison, KR Whiteman, A Wilhelm, ...
Molecular Pharmaceutics 16 (9), 3926-3937, 2019
342019
Site-specific conjugation of the indolinobenzodiazepine DGN549 to antibodies affords antibody–drug conjugates with an improved therapeutic index as compared with lysine conjugation
C Bai, EE Reid, A Wilhelm, M Shizuka, EK Maloney, R Laleau, L Harvey, ...
Bioconjugate Chemistry 31 (1), 93-103, 2019
272019
Selective Protein− Protein Interactions Driven by a Phenylalanine Interface
NC Yoder, K Kumar
Journal of the American Chemical Society 128 (1), 188-191, 2006
262006
Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates
KC Catcott, MA McShea, CU Bialucha, KL Miller, SW Hicks, P Saxena, ...
MAbs 8 (3), 513-523, 2016
212016
Using sortases to install click chemistry handles for protein ligation
HL Ploegh, MD Witte, NC Yoder
US Patent 11,028,185, 2021
182021
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