Automated on-chip rapid microscopy, phenotyping and sorting of C. elegans K Chung*, MM Crane*, H Lu Nature methods 5 (7), 637-643, 2008 | 443 | 2008 |
Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans JN Stirman, MM Crane, SJ Husson, S Wabnig, C Schultheis, A Gottschalk, ... Nature methods 8 (2), 153-158, 2011 | 267 | 2011 |
A microfluidic system for studying ageing and dynamic single-cell responses in budding yeast MM Crane, IBN Clark, E Bakker, S Smith, PS Swain PloS one 9 (6), e100042, 2014 | 167 | 2014 |
A conserved role for atlastin GTPases in regulating lipid droplet size RW Klemm, JP Norton, RA Cole, CS Li, SH Park, MM Crane, L Li, D Jin, ... Cell reports 3 (5), 1465-1475, 2013 | 149 | 2013 |
Microfluidics-enabled phenotyping, imaging, and screening of multicellular organisms MM Crane, K Chung, J Stirman, H Lu Lab on a Chip 10 (12), 1509-1517, 2010 | 149 | 2010 |
Autonomous screening implicates new genes in synaptogenesis of C. elegans MM Crane, JN Stirman, CY Ou, PT Kurshan, JM Rehg, K Shen, H Lu Nature methods 9 (10), 977, 2012 | 133* | 2012 |
Computer-enhanced high-throughput genetic screens of C. elegans in a microfluidic system MM Crane, K Chung, H Lu Lab on a Chip 9 (1), 38-40, 2009 | 104 | 2009 |
Microfluidic technologies for yeast replicative lifespan studies KL Chen, MM Crane, M Kaeberlein Mechanisms of ageing and development 161, 262-269, 2017 | 87 | 2017 |
A multispectral optical illumination system with precise spatiotemporal control for the manipulation of optogenetic reagents JN Stirman, MM Crane, SJ Husson, A Gottschalk, H Lu Nature protocols 7 (2), 207-220, 2012 | 77 | 2012 |
Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics IL Rempel, MM Crane, DJ Thaller, A Mishra, DPM Jansen, G Janssens, ... Elife 8, e48186, 2019 | 71 | 2019 |
Distributing tasks via multiple input pathways increase cellular survival in stress AA Granados*, MM Crane*, LF Montano-Gutierrez, RJ Tanaka, M Voliotis, ... eLife 6, e21415, 2017 | 53 | 2017 |
Transition between fermentation and respiration determines history-dependent behavior in fluctuating carbon sources B Cerulus, A Jariani, G Perez-Samper, L Vermeersch, JMJ Pietsch, ... Elife 7, e39234, 2018 | 52 | 2018 |
Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans CF Bennett, JJ Kwon, C Chen, J Russell, K Acosta, N Burnaevskiy, ... PLoS genetics 13 (3), e1006695, 2017 | 51 | 2017 |
Morphologically constrained and data informed cell segmentation of budding yeast E Bakker, PS Swain, MM Crane Bioinformatics 34 (1), 88-96, 2018 | 41 | 2018 |
Deep phenotyping unveils hidden traits and genetic relations in subtle mutants A San-Miguel, PT Kurshan, MM Crane, Y Zhao, PT McGrath, K Shen, H Lu Nature communications 7 (1), 12990, 2016 | 41 | 2016 |
A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast SN Mouton, DJ Thaller, MM Crane, IL Rempel, OT Terpstra, A Steen, ... Elife 9, e54707, 2020 | 38 | 2020 |
Regulation of synaptic extracellular matrix composition is critical for proper synapse morphology PT Kurshan, AQ Phan, GJ Wang, MM Crane, H Lu, K Shen Journal of Neuroscience 34 (38), 12678-12689, 2014 | 38 | 2014 |
Quantitative screening of genes regulating tryptophan hydroxylase transcription in C. elegans using microfluidics and adaptive algorithm L Hyewon, MM Crane, Y Zhang, H Lu Integrative Biology, 372-380, 2013 | 33* | 2013 |
In vivo measurements reveal a single 5′-intron is sufficient to increase protein expression level in Caenorhabditis elegans MM Crane, B Sands, C Battaglia, B Johnson, S Yun, M Kaeberlein, ... Scientific reports 9 (1), 9192, 2019 | 32 | 2019 |
DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging MM Crane, AE Russell, BJ Schafer, BW Blue, R Whalen, J Almazan, ... Elife 8, e50778, 2019 | 30 | 2019 |