Integrative analysis identifies four molecular and clinical subsets in uveal melanoma AG Robertson, J Shih, C Yau, EA Gibb, J Oba, KL Mungall, JM Hess, ... Cancer cell 32 (2), 204-220. e15, 2017 | 847 | 2017 |
Systematic analysis of telomere length and somatic alterations in 31 cancer types FP Barthel, W Wei, M Tang, E Martinez-Ledesma, X Hu, SB Amin, ... Nature genetics 49 (3), 349-357, 2017 | 579 | 2017 |
KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer W Liao, MJ Overman, AT Boutin, X Shang, DI Zhao, P Dey, J Li, G Wang, ... Cancer cell 35 (4), 559-572. e7, 2019 | 442 | 2019 |
Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC X Le, S Puri, MV Negrao, MB Nilsson, J Robichaux, T Boyle, JK Hicks, ... Clinical Cancer Research 24 (24), 6195-6203, 2018 | 347 | 2018 |
Suppression of type I IFN signaling in tumors mediates resistance to anti-PD-1 treatment that can be overcome by radiotherapy X Wang, JE Schoenhals, A Li, DR Valdecanas, H Ye, F Zang, C Tang, ... Cancer research 77 (4), 839-850, 2017 | 223 | 2017 |
TumorFusions: an integrative resource for cancer-associated transcript fusions X Hu, Q Wang, M Tang, F Barthel, S Amin, K Yoshihara, FM Lang, ... Nucleic acids research 46 (D1), D1144-D1149, 2018 | 205 | 2018 |
Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer D Zhao, X Lu, G Wang, Z Lan, W Liao, J Li, X Liang, JR Chen, S Shah, ... Nature 542 (7642), 484-488, 2017 | 192 | 2017 |
KMT2D deficiency impairs super-enhancers to confer a glycolytic vulnerability in lung cancer H Alam, M Tang, M Maitituoheti, SS Dhar, M Kumar, CY Han, CR Ambati, ... Cancer cell 37 (4), 599-617. e7, 2020 | 163 | 2020 |
The tandem duplicator phenotype is a prevalent genome-wide cancer configuration driven by distinct gene mutations F Menghi, FP Barthel, V Yadav, M Tang, B Ji, Z Tang, GW Carter, Y Ruan, ... Cancer cell 34 (2), 197-210. e5, 2018 | 149 | 2018 |
Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response KC Johnson, KJ Anderson, ET Courtois, AD Gujar, FP Barthel, FS Varn, ... Nature genetics 53 (10), 1456-1468, 2021 | 142 | 2021 |
Integrative analyses of single-cell transcriptome and regulome using MAESTRO C Wang, D Sun, X Huang, C Wan, Z Li, Y Han, Q Qin, J Fan, X Qiu, Y Xie, ... Genome biology 21, 1-28, 2020 | 133 | 2020 |
Tumor microenvironment remodeling enables bypass of oncogenic KRAS dependency in pancreatic cancer P Hou, A Kapoor, Q Zhang, J Li, CJ Wu, J Li, Z Lan, M Tang, X Ma, ... Cancer discovery 10 (7), 1058-1077, 2020 | 99 | 2020 |
TRIM29 suppresses TWIST1 and invasive breast cancer behavior L Ai, WJ Kim, M Alpay, M Tang, CE Pardo, S Hatakeyama, WS May, ... Cancer research 74 (17), 4875-4887, 2014 | 94 | 2014 |
USP1 inhibition destabilizes KPNA2 and suppresses breast cancer metastasis A Ma, M Tang, L Zhang, B Wang, Z Yang, Y Liu, G Xu, L Wu, T Jing, X Xu, ... Oncogene 38 (13), 2405-2419, 2019 | 90 | 2019 |
MOF acetylates the histone demethylase LSD1 to suppress epithelial-to-mesenchymal transition H Luo, AK Shenoy, X Li, Y Jin, L Jin, Q Cai, M Tang, Y Liu, H Chen, ... Cell reports 15 (12), 2665-2678, 2016 | 89 | 2016 |
Epithelial-to-mesenchymal transition confers pericyte properties on cancer cells AK Shenoy, Y Jin, H Luo, M Tang, C Pampo, R Shao, DW Siemann, L Wu, ... The Journal of clinical investigation 126 (11), 4174-4186, 2016 | 78 | 2016 |
Evaluating single-cell cluster stability using the Jaccard similarity index M Tang, Y Kaymaz, BL Logeman, S Eichhorn, ZS Liang, C Dulac, ... Bioinformatics 37 (15), 2212-2214, 2021 | 59 | 2021 |
Fast alignment and preprocessing of chromatin profiles with Chromap H Zhang, L Song, X Wang, H Cheng, C Wang, CA Meyer, T Liu, M Tang, ... Nature communications 12 (1), 6566, 2021 | 56 | 2021 |
The malignant brain tumor (MBT) domain protein SFMBT1 is an integral histone reader subunit of the LSD1 demethylase complex for chromatin association and epithelial-to … M Tang, H Shen, Y Jin, T Lin, Q Cai, MA Pinard, S Biswas, Q Tran, G Li, ... Journal of Biological Chemistry 288 (38), 27680-27691, 2013 | 52 | 2013 |
Enhancer reprogramming confers dependence on glycolysis and IGF signaling in KMT2D mutant melanoma M Maitituoheti, EZ Keung, M Tang, L Yan, H Alam, G Han, AK Singh, ... Cell reports 33 (3), 2020 | 50 | 2020 |