Crystal structures of a ZIP zinc transporter reveal a binuclear metal center in the transport pathway T Zhang, J Liu, M Fellner, C Zhang, D Sui, J Hu Science advances 3 (8), e1700344, 2017 | 159 | 2017 |
An iron–oxygen intermediate formed during the catalytic cycle of cysteine dioxygenase EP Tchesnokov, AS Faponle, CG Davies, MG Quesne, R Turner, ... Chemical Communications 52 (57), 8814-8817, 2016 | 78 | 2016 |
Identification of highly selective covalent inhibitors by phage display S Chen, S Lovell, S Lee, M Fellner, PD Mace, M Bogyo Nature biotechnology 39 (4), 490-498, 2021 | 77 | 2021 |
Structures and mechanisms of the non-heme Fe (II)-and 2-oxoglutarate-dependent ethylene-forming enzyme: substrate binding creates a twist S Martinez, M Fellner, CQ Herr, A Ritchie, J Hu, RP Hausinger Journal of the American Chemical Society 139 (34), 11980-11988, 2017 | 62 | 2017 |
The cysteine dioxygenase homologue from Pseudomonas aeruginosa is a 3-mercaptopropionate dioxygenase EP Tchesnokov, M Fellner, E Siakkou, T Kleffmann, LW Martin, S Aloi, ... Journal of Biological Chemistry 290 (40), 24424-24437, 2015 | 56 | 2015 |
Lanthanide-dependent alcohol dehydrogenases require an essential aspartate residue for metal coordination and enzymatic function NM Good, M Fellner, K Demirer, J Hu, RP Hausinger, ... Journal of Biological Chemistry 295 (24), 8272-8284, 2020 | 42 | 2020 |
Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase B Desguin, M Fellner, O Riant, J Hu, RP Hausinger, P Hols, P Soumillion Journal of Biological Chemistry 293 (32), 12303-12317, 2018 | 41 | 2018 |
The Cys-Tyr cross-link of cysteine dioxygenase changes the optimal pH of the reaction without a structural change CG Davies, M Fellner, EP Tchesnokov, SM Wilbanks, GNL Jameson Biochemistry 53 (50), 7961-7968, 2014 | 41 | 2014 |
Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE M Fellner, B Desguin, RP Hausinger, J Hu Proceedings of the National Academy of Sciences 114 (34), 9074-9079, 2017 | 37 | 2017 |
Lactate racemase nickel-pincer cofactor operates by a proton-coupled hydride transfer mechanism JA Rankin, RC Mauban, M Fellner, B Desguin, J McCracken, J Hu, ... Biochemistry 57 (23), 3244-3251, 2018 | 30 | 2018 |
Influence of cysteine 164 on active site structure in rat cysteine dioxygenase M Fellner, E Siakkou, AS Faponle, EP Tchesnokov, SP de Visser, ... JBIC Journal of Biological Inorganic Chemistry 21, 501-510, 2016 | 23 | 2016 |
Substrate and pH-Dependent Kinetic Profile of 3-Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa M Fellner, S Aloi, EP Tchesnokov, SM Wilbanks, GNL Jameson Biochemistry 55 (9), 1362-1371, 2016 | 23 | 2016 |
Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases B Desguin, J Urdiain-Arraiza, M Da Costa, M Fellner, J Hu, RP Hausinger, ... Scientific reports 10 (1), 18123, 2020 | 19 | 2020 |
Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum M Fellner, JA Rankin, B Desguin, J Hu, RP Hausinger Biochemistry 57 (38), 5513-5523, 2018 | 18 | 2018 |
A structural perspective on the PP-loop ATP pyrophosphatase family M Fellner, RP Hausinger, J Hu Critical reviews in biochemistry and molecular biology 53 (6), 607-622, 2018 | 17 | 2018 |
Recurrent de novo missense variants across multiple histone H4 genes underlie a neurodevelopmental syndrome F Tessadori, K Duran, K Knapp, M Fellner, S Smithson, AB Meireles, ... The American Journal of Human Genetics 109 (4), 750-758, 2022 | 16 | 2022 |
A chromogenic assay of substrate depletion by thiol dioxygenases M Fellner, LM Doughty, GNL Jameson, SM Wilbanks Analytical biochemistry 459, 56-60, 2014 | 16 | 2014 |
Nickel–pincer nucleotide cofactor RP Hausinger, B Desguin, M Fellner, JA Rankin, J Hu Current Opinion in Chemical Biology 47, 18-23, 2018 | 15 | 2018 |
Altered structure and dynamics of pathogenic cytochrome c variants correlate with increased apoptotic activity M Fellner, R Parakra, KO McDonald, I Kass, GNL Jameson, SM Wilbanks, ... Biochemical Journal 478 (3), 669-684, 2021 | 14 | 2021 |
Structural Basis for the Inhibitor and Substrate Specificity of the Unique Fph Serine Hydrolases of Staphylococcus aureus M Fellner, CS Lentz, SA Jamieson, JL Brewster, L Chen, M Bogyo, ... ACS Infectious Diseases 6 (10), 2771-2782, 2020 | 14 | 2020 |