| Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase GK Dhoot, MK Gustafsson, X Ai, W Sun, DM Standiford, CP Emerson Jr Science 293 (5535), 1663-1666, 2001 | 549 | 2001 |
| Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling NA Riobo, K Lu, X Ai, GM Haines, CP Emerson Jr Proceedings of the National Academy of Sciences 103 (12), 4505-4510, 2006 | 525 | 2006 |
| QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling X Ai, AT Do, O Lozynska, M Kusche-Gullberg, U Lindahl, CP Emerson Jr The Journal of cell biology 162 (2), 341-351, 2003 | 501 | 2003 |
| QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis S Wang, X Ai, SD Freeman, ME Pownall, Q Lu, DS Kessler, ... Proceedings of the National Academy of Sciences 101 (14), 4833-4838, 2004 | 242 | 2004 |
| Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2 X Ai, AT Do, M Kusche-Gullberg, U Lindahl, K Lu, CP Emerson Journal of Biological Chemistry 281 (8), 4969-4976, 2006 | 191 | 2006 |
| SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation X Ai, T Kitazawa, AT Do, M Kusche-Gullberg, PA Labosky, CP Emerson Jr Oxford University Press for The Company of Biologists Limited 134 (18), 3327 …, 2007 | 176 | 2007 |
| Ventral neural progenitors switch toward an oligodendroglial fate in response to increased Sonic hedgehog (Shh) activity: involvement of Sulfatase 1 in modulating Shh signaling … C Danesin, E Agius, N Escalas, X Ai, C Emerson, P Cochard, C Soula Journal of Neuroscience 26 (19), 5037-5048, 2006 | 139 | 2006 |
| A Shh/miR-206/BDNF cascade coordinates innervation and formation of airway smooth muscle K Radzikinas, L Aven, Z Jiang, T Tran, J Paez-Cortez, K Boppidi, J Lu, ... Journal of Neuroscience 31 (43), 15407-15415, 2011 | 100 | 2011 |
| Derivation of lung mesenchymal lineages from the fetal mesothelium requires hedgehog signaling for mesothelial cell entry R Dixit, X Ai, A Fine Development 140 (21), 4398-4406, 2013 | 99 | 2013 |
| Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation RE Abdulnour, HP Sham, DN Douda, RA Colas, J Dalli, Y Bai, X Ai, ... Mucosal immunology 9 (5), 1278-1287, 2016 | 98 | 2016 |
| Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration A Langsdorf, AT Do, M Kusche-Gullberg, CP Emerson Jr, X Ai Developmental Biology 311 (2), 464-477, 2007 | 82 | 2007 |
| A mutant-cell library for systematic analysis of heparan sulfate structure–function relationships H Qiu, S Shi, J Yue, M Xin, AV Nairn, L Lin, X Liu, G Li, ... Nature methods 15 (11), 889-899, 2018 | 77 | 2018 |
| Age-related dopaminergic innervation augments T helper 2-type allergic inflammation in the postnatal lung W Wang, JA Cohen, A Wallrapp, KG Trieu, J Barrios, F Shao, ... Immunity 51 (6), 1102-1118. e7, 2019 | 69 | 2019 |
| Genetic control of fatty acid β-oxidation in chronic obstructive pulmonary disease Z Jiang, NH Knudsen, G Wang, W Qiu, ZZC Naing, Y Bai, X Ai, CH Lee, ... American journal of respiratory cell and molecular biology 56 (6), 738-748, 2017 | 69 | 2017 |
| WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier VA Schumacher, U Schlötzer-Schrehardt, SA Karumanchi, X Shi, J Zaia, ... Journal of the American Society of Nephrology 22 (7), 1286-1296, 2011 | 68 | 2011 |
| Cryopreserved human precision-cut lung slices as a bioassay for live tissue banking. A viability study of bronchodilation with bitter-taste receptor agonists Y Bai, N Krishnamoorthy, KR Patel, I Rosas, MJ Sanderson, X Ai American journal of respiratory cell and molecular biology 54 (5), 656-663, 2016 | 67 | 2016 |
| Airway contractility in the precision-cut lung slice after cryopreservation SR Rosner, S Ram-Mohan, JR Paez-Cortez, TL Lavoie, ML Dowell, ... American journal of respiratory cell and molecular biology 50 (5), 876-881, 2014 | 62 | 2014 |
| Pulmonary neuroendocrine cells secrete γ-aminobutyric acid to induce goblet cell hyperplasia in primate models J Barrios, AT Kho, L Aven, JA Mitchel, JA Park, SH Randell, LA Miller, ... American journal of respiratory cell and molecular biology 60 (6), 687-694, 2019 | 60 | 2019 |
| Heparan sulfate 6-O-endosulfatases (Sulfs) coordinate the Wnt signaling pathways to regulate myoblast fusion during skeletal muscle regeneration TH Tran, X Shi, J Zaia, X Ai Journal of Biological Chemistry 287 (39), 32651-32664, 2012 | 57 | 2012 |
| An NT4/TrkB-dependent increase in innervation links early-life allergen exposure to persistent airway hyperreactivity L Aven, J Paez-Cortez, R Achey, R Krishnan, S Ram-Mohan, ... The FASEB Journal 28 (2), 897, 2014 | 56 | 2014 |
