Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission DM Pereira, F Ferreres, JMA Oliveira, L Gaspar, J Faria, P Valentão, ... Phytomedicine 17 (8-9), 646-652, 2010 | 135 | 2010 |
Codon usage bias controls mRNA and protein abundance in trypanosomatids L Jeacock, J Faria, D Horn Elife 7, e32496, 2018 | 98 | 2018 |
Boerhaavia diffusa: Metabolite profiling of a medicinal plant from Nyctaginaceae DM Pereira, J Faria, L Gaspar, P Valentão, PB Andrade Food and Chemical Toxicology 47 (8), 2142-2149, 2009 | 78 | 2009 |
Exploiting Catharanthus roseus roots: Source of antioxidants DM Pereira, J Faria, L Gaspar, F Ferreres, P Valentão, M Sottomayor, ... Food chemistry 121 (1), 56-61, 2010 | 73 | 2010 |
Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex J Faria, L Glover, S Hutchinson, C Boehm, MC Field, D Horn Nature communications 10 (1), 1-14, 2019 | 67 | 2019 |
Phytochemical investigations and biological potential screening with cellular and non-cellular models of globe amaranth (Gomphrena globosaL.) inflorescences LR Silva, P Valentão, J Faria, F Ferreres, C Sousa, A Gil-Izquierdo, ... Food chemistry 135 (2), 756-763, 2012 | 55 | 2012 |
Simple and reproducible HPLC–DAD–ESI-MS/MS analysis of alkaloids in Catharanthus roseus roots F Ferreres, DM Pereira, P Valentão, JMA Oliveira, J Faria, L Gaspar, ... Journal of pharmaceutical and biomedical analysis 51 (1), 65-69, 2010 | 55 | 2010 |
Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes J Faria, V Luzak, LSM Müller, BG Brink, S Hutchinson, L Glover, D Horn, ... Nature Microbiology 6 (3), 289-300, 2021 | 53 | 2021 |
Drug Discovery for Human African Trypanosomiasis: Identification of Novel Scaffolds by the Newly Developed HTS SYBR Green Assay for Trypanosoma brucei J Faria, CB Moraes, R Song, BS Pascoalino, N Lee, JL Siqueira-Neto, ... Journal of biomolecular screening 20 (1), 70-81, 2015 | 45 | 2015 |
Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei J Kovářová, R Nagar, J Faria, MAJ Ferguson, MP Barrett, D Horn PLoS pathogens 14 (12), e1007475, 2018 | 44 | 2018 |
Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids J Faria, I Loureiro, N Santarém, P Cecílio, S Macedo-Ribeiro, J Tavares, ... Scientific reports 6 (1), 1-16, 2016 | 35 | 2016 |
Ribose 5-Phosphate Isomerase B Knockdown Compromises Trypanosoma brucei Bloodstream Form Infectivity I Loureiro, J Faria, C Clayton, S Macedo-Ribeiro, N Santarem, N Roy, ... PLoS neglected tropical diseases 9 (1), e3430, 2015 | 26 | 2015 |
Correction: Knockdown of Asparagine Synthetase A Renders Auxotrophic to Asparagine. I Loureiro, J Faria, C Clayton, SM Ribeiro, N Roy, N Santarém, J Tavares, ... Plos Neglected Tropical Diseases 7 (12), 2013 | 25* | 2013 |
Knockdown of Asparagine Synthetase A Renders Trypanosoma brucei Auxotrophic to Asparagine I Loureiro, J Faria, C Clayton, SM Ribeiro, N Roy, N Santarém, J Tavares, ... PLoS neglected tropical diseases 7 (12), e2578, 2013 | 25 | 2013 |
Potential drug targets in the pentose phosphate pathway of trypanosomatids I Loureiro, J Faria, N Santarem, TK Smith, J Tavares, A Cordeiro-da-Silva Current medicinal chemistry 25 (39), 5239-5265, 2018 | 19 | 2018 |
The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design C Ronin, DM Costa, J Tavares, J Faria, F Ciesielski, P Ciapetti, TK Smith, ... PloS one 13 (3), e0193602, 2018 | 17 | 2018 |
Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity J Faria, I Loureiro, N Santarem, S Macedo-Ribeiro, J Tavares, ... PLoS neglected tropical diseases 10 (1), e0004365, 2016 | 14 | 2016 |
Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome J Faria, EM Briggs, JA Black, R McCulloch | 13 | 2022 |
A nuclear enterprise: zooming in on nuclear organization and gene expression control in the African trypanosome JRC Faria Parasitology, 1-17, 2021 | 7 | 2021 |
CRISPR/Cas9-based precision tagging of essential genes in bloodstream form African trypanosomes J Kovářová, M Novotná, J Faria, E Rico, C Wallace, M Zoltner, MC Field, ... Molecular and Biochemical Parasitology 249, 111476, 2022 | 5 | 2022 |