Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways WRJD Galloway, JT Hodgkinson, SD Bowden, M Welch, DR Spring Chemical reviews 111 (1), 28-67, 2011 | 755 | 2011 |
Combating multidrug‐resistant bacteria: current strategies for the discovery of novel antibacterials KMG O'Connell, JT Hodgkinson, HF Sore, M Welch, GPC Salmond, ... Angewandte Chemie International Edition 52 (41), 10706-10733, 2013 | 444 | 2013 |
Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria WRJD Galloway, JT Hodgkinson, S Bowden, M Welch, DR Spring Trends in microbiology 20 (9), 449-458, 2012 | 245 | 2012 |
Diversity-oriented synthesis of macrocyclic peptidomimetics A Isidro-Llobet, T Murillo, P Bello, A Cilibrizzi, JT Hodgkinson, ... Proceedings of the National Academy of Sciences 108 (17), 6793-6798, 2011 | 128 | 2011 |
Siderophore–antibiotic conjugate design: New drugs for bad bugs? KH Negash, JKS Norris, JT Hodgkinson Molecules 24 (18), 3314, 2019 | 124 | 2019 |
PROTAC-mediated degradation of class I histone deacetylase enzymes in corepressor complexes KS James, WR John, S MichaeláCowley Chemical Communications 56 (32), 4476-4479, 2020 | 93 | 2020 |
Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics B Morkunas, WRJD Galloway, M Wright, BM Ibbeson, JT Hodgkinson, ... Organic & Biomolecular Chemistry 10 (42), 8452-8464, 2012 | 92 | 2012 |
Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa JT Hodgkinson, WRJD Galloway, M Wright, IK Mati, RL Nicholson, ... Organic & biomolecular chemistry 10 (30), 6032-6044, 2012 | 83 | 2012 |
Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation Z Walsh, ER Janeček, JT Hodgkinson, J Sedlmair, A Koutsioubas, ... Proceedings of the National Academy of Sciences 111 (50), 17743-17748, 2014 | 80 | 2014 |
Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule J Hodgkinson, SD Bowden, WRJD Galloway, DR Spring, M Welch Journal of bacteriology 192 (14), 3833-3837, 2010 | 69 | 2010 |
Diversity‐oriented synthesis of drug‐like macrocyclic scaffolds using an orthogonal organo‐and metal catalysis strategy A Grossmann, S Bartlett, M Janecek, JT Hodgkinson, DR Spring Angewandte Chemie 126 (48), 13309-13313, 2014 | 62 | 2014 |
Microwave and flow syntheses of Pseudomonas quinolone signal (PQS) and analogues JT Hodgkinson, WRJD Galloway, S Saraf, IR Baxendale, SV Ley, ... Organic & Biomolecular Chemistry 9 (1), 57-61, 2011 | 62 | 2011 |
2-Heptyl-4-quinolone, a precursor of the Pseudomonas quinolone signal molecule, modulates swarming motility in Pseudomonas aeruginosa DG Ha, JH Merritt, TH Hampton, JT Hodgkinson, M Janecek, DR Spring, ... Journal of bacteriology 193 (23), 6770-6780, 2011 | 55 | 2011 |
A new Pseudomonas quinolone signal (PQS) binding partner: MexG JT Hodgkinson, J Gross, YR Baker, DR Spring, M Welch Chemical science 7 (4), 2553-2562, 2016 | 52 | 2016 |
Robust routes for the synthesis of N-acylated-L-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity JT Hodgkinson, WRJD Galloway, M Casoli, H Keane, X Su, ... Tetrahedron letters 52 (26), 3291-3294, 2011 | 50 | 2011 |
Learning the language of bacteria JT Hodgkinson, M Welch, DR Spring ACS Chemical Biology 2 (11), 715-717, 2007 | 46 | 2007 |
Optimization of class I histone deacetylase PROTACs reveals that HDAC1/2 degradation is critical to induce apoptosis and cell arrest in cancer cells JP Smalley, IM Baker, WA Pytel, LY Lin, KJ Bowman, JWR Schwabe, ... Journal of medicinal chemistry 65 (7), 5642-5659, 2022 | 44 | 2022 |
Controlling the contents of microdroplets by exploiting the permeability of PDMS J Shim, SN Patil, JT Hodgkinson, SD Bowden, DR Spring, M Welch, ... Lab on a Chip 11 (6), 1132-1137, 2011 | 44 | 2011 |
Bifunctional HDAC therapeutics: one drug to rule them all? JP Smalley, SM Cowley, JT Hodgkinson Molecules 25 (19), 4394, 2020 | 39 | 2020 |
Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes YR Baker, JT Hodgkinson, BI Florea, E Alza, W Galloway, L Grimm, ... Chemical Science 8 (11), 7403-7411, 2017 | 34 | 2017 |