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Kevin Christopher Ludwig
Kevin Christopher Ludwig
在 uni-bonn.de 的电子邮件经过验证
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Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids
F Grein, A Müller, KM Scherer, X Liu, KC Ludwig, A Klöckner, M Strach, ...
Nature communications 11 (1), 1455, 2020
1822020
Host defense peptides: Dual antimicrobial and immunomodulatory action
M Drayton, JP Deisinger, KC Ludwig, N Raheem, A Müller, T Schneider, ...
International Journal of Molecular Sciences 22 (20), 11172, 2021
652021
The lasso peptide siamycin-I targets lipid II at the Gram-positive cell surface
S Tan, KC Ludwig, A Müller, T Schneider, JR Nodwell
ACS Chemical Biology 14 (5), 966-974, 2019
422019
An antibiotic from an uncultured bacterium binds to an immutable target
R Shukla, AJ Peoples, KC Ludwig, S Maity, MGN Derks, S De Benedetti, ...
Cell 186 (19), 4059-4073. e27, 2023
312023
Biosynthesis and mechanism of action of the cell wall targeting antibiotic hypeptin
DA Wirtz, KC Ludwig, M Arts, CE Marx, S Krannich, P Barac, S Kehraus, ...
Angewandte Chemie International Edition 60 (24), 13579-13586, 2021
222021
Steroids originating from bacterial bile acid degradation affect Caenorhabditis elegans and indicate potential risks for the fauna of manured soils
MN Mendelski, R Dölling, FM Feller, D Hoffmann, L Ramos Fangmeier, ...
Scientific Reports 9 (1), 11120, 2019
192019
A novel steroid-coenzyme A ligase from Novosphingobium sp. strain Chol11 is essential for an alternative degradation pathway for bile salts
O Yücel, J Holert, KC Ludwig, S Thierbach, B Philipp
Applied and Environmental Microbiology 84 (1), e01492-17, 2018
112018
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates
E Reithuber, T Wixe, KC Ludwig, A Müller, H Uvell, F Grein, AEG Lindgren, ...
Proceedings of the National Academy of Sciences 118 (47), e2108244118, 2021
82021
Impacts of NaHCO3 on β-Lactam Binding to PBP2a Protein Variants Associated with the NaHCO3-Responsive versus NaHCO3-Non-Responsive Phenotypes
SC Ersoy, LC Chan, MR Yeaman, HF Chambers, RA Proctor, KC Ludwig, ...
Antibiotics 11 (4), 462, 2022
62022
Ca (2+)-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids. Nat Commun 2020; 11: 1455
F Grein, A Müller, KM Scherer, X Liu, KC Ludwig, A Klöckner
Epub 2020/03/21. doi: 10.1038/s41467-020-15257-1 32193379, 0
6
A new antibiotic from an uncultured bacterium binds to an immutable target
R Shukla, AJ Peoples, KC Ludwig, S Maity, MGN Derks, S de Benedetti, ...
bioRxiv, 2023
12023
Investigations on the Degradation of the Bile Salt Cholate via the 9,10-Seco-Pathway Reveals the Formation of a Novel Recalcitrant Steroid Compound by a Side Reaction in …
FM Feller, S Eilebrecht, R Nedielkov, O Yücel, J Alvincz, G Salinas, ...
Microorganisms 9 (10), 2146, 2021
12021
Synthesis of Bisindole Alkaloids and Their Mode of Action against Methicillin-Resistant Staphylococcus Aureus
ET Adeniyi, M Kruppa, S De Benedetti, KC Ludwig, V Krisilia, ...
ACS Infectious Diseases, 2024
2024
An antibiotic from an uncultured bacterium binds to an immutable target
K Nieselt, R Shukla, AJ Peoples, KC Ludwig, S Maity, MGN Derks, ...
Cell 186 (19), 2023
2023
Lipid II-binding antibiotics–differential antibiotic activities beyond sequestration of the central peptidoglycan precursor
KC Ludwig
Universitäts-und Landesbibliothek Bonn, 2023
2023
THCz
E Reithuber, T Wixe, KC Ludwig, A Müller, H Uvell, F Grein, AEG Lindgren, ...
Proceedings of the National Academy of Sciences of the United States of …, 2021
2021
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