Megalin and cubilin in proximal tubule protein reabsorption: from experimental models to human disease R Nielsen, EI Christensen, H Birn Kidney international 89 (1), 58-67, 2016 | 451 | 2016 |
Attenuation of c GAS‐STING signaling is mediated by a p62/SQSTM 1‐dependent autophagy pathway activated by TBK1 T Prabakaran, C Bodda, C Krapp, B Zhang, MH Christensen, C Sun, ... The EMBO journal 37 (8), e97858, 2018 | 355 | 2018 |
Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules EI Christensen, O Devuyst, G Dom, R Nielsen, P Van Der Smissen, ... Proceedings of the National Academy of Sciences 100 (14), 8472-8477, 2003 | 337 | 2003 |
Cubilin is essential for albumin reabsorption in the renal proximal tubule S Amsellem, J Gburek, G Hamard, R Nielsen, TE Willnow, O Devuyst, ... Journal of the American Society of Nephrology 21 (11), 1859-1867, 2010 | 334 | 2010 |
Endocytic receptors in the renal proximal tubule EI Christensen, H Birn, T Storm, K Weyer, R Nielsen Physiology 27 (4), 223-236, 2012 | 317 | 2012 |
Receptor-mediated endocytosis in renal proximal tubule EI Christensen, PJ Verroust, R Nielsen Pflügers Archiv-European Journal of Physiology 458, 1039-1048, 2009 | 289 | 2009 |
Listeria monocytogenes induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway K Hansen, T Prabakaran, A Laustsen, SE Jørgensen, SH Rahbæk, ... The EMBO journal 33 (15), 1654-1666, 2014 | 268 | 2014 |
Cubilin-and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney XY Zhai, R Nielsen, H Birn, K Drumm, S Mildenberger, R Freudinger, ... Kidney international 58 (4), 1523-1533, 2000 | 260 | 2000 |
The tandem endocytic receptors megalin and cubilin are important proteins in renal pathology PJ Verroust, H Birn, R Nielsen, R Kozyraki, EI Christensen Kidney international 62 (3), 745-756, 2002 | 185 | 2002 |
Transforming growth factor‐β1 reduces megalin‐ and cubilin‐mediated endocytosis of albumin in proximal‐tubule‐derived opossum kidney cells M Gekle, P Knaus, R Nielsen, S Mildenberger, R Freudinger, V Wohlfarth, ... The Journal of physiology 552 (2), 471-481, 2003 | 147 | 2003 |
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease T Prabakaran, R Nielsen, JV Larsen, SS Sørensen, UF Rasmussen, ... PloS one 6 (9), e25065, 2011 | 134 | 2011 |
Proteinuria and events beyond the slit R Nielsen, EI Christensen Pediatric nephrology 25, 813-822, 2010 | 129 | 2010 |
Megalin antagonizes activation of the parathyroid hormone receptor J Hilpert, A Nykjaer, C Jacobsen, G Wallukat, R Nielsen, SK Moestrup, ... Journal of Biological Chemistry 274 (9), 5620-5625, 1999 | 120 | 1999 |
Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells R Nielsen, PJ Courtoy, C Jacobsen, G Dom, WR Lima, M Jadot, ... Proceedings of the National Academy of Sciences 104 (13), 5407-5412, 2007 | 117 | 2007 |
Mutually dependent localization of megalin and Dab2 in the renal proximal tubule J Nagai, EI Christensen, SM Morris, TE Willnow, JA Cooper, R Nielsen American Journal of Physiology-Renal Physiology 289 (3), F569-F576, 2005 | 109 | 2005 |
Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing S Gao, S Hein, F Dagnæs-Hansen, K Weyer, C Yang, R Nielsen, ... Theranostics 4 (10), 1039, 2014 | 104 | 2014 |
Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B12 H Birn, TE Willnow, R Nielsen, AGW Norden, C Bönsch, SK Moestrup, ... American Journal of Physiology-Renal Physiology 282 (3), F408-F416, 2002 | 104 | 2002 |
Characterization of a kidney proximal tubule cell line, LLC-PK1, expressing endocytotic active megalin. R Nielsen, H Birn, SK Moestrup, M Nielsen, P Verroust, EI Christensen Journal of the American Society of Nephrology 9 (10), 1767-1776, 1998 | 102 | 1998 |
Renal phenotypic investigations of megalin-deficient patients: novel insights into tubular proteinuria and albumin filtration T Storm, L Tranebjærg, C Frykholm, H Birn, PJ Verroust, T Nevéus, ... Nephrology Dialysis Transplantation 28 (3), 585-591, 2013 | 88 | 2013 |
Renal uptake of 99mTc-dimercaptosuccinic acid is dependent on normal proximal tubule receptor–mediated endocytosis K Weyer, R Nielsen, SV Petersen, EI Christensen, M Rehling, H Birn Journal of Nuclear Medicine 54 (1), 159-165, 2013 | 85 | 2013 |