| Discovery of a small molecule insulin mimetic with antidiabetic activity in mice B Zhang, G Salituro, D Szalkowski, Z Li, Y Zhang, I Royo, D Vilella, ... Science 284 (5416), 974-977, 1999 | 658 | 1999 |
| Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity EL Air, MZ Strowski, SC Benoit, SL Conarello, GM Salituro, XM Guan, ... Nature medicine 8 (2), 179-183, 2002 | 264 | 2002 |
| Selective small-molecule agonists of G protein–coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice CP Tan, Y Feng, YP Zhou, GJ Eiermann, A Petrov, C Zhou, S Lin, ... Diabetes 57 (8), 2211-2219, 2008 | 213 | 2008 |
| Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes T Biftu, R Sinha-Roy, P Chen, X Qian, D Feng, JT Kuethe, G Scapin, ... Journal of Medicinal Chemistry 57 (8), 3205-3212, 2014 | 197 | 2014 |
| Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes M Wu, SB Singh, J Wang, CC Chung, G Salituro, BV Karanam, SH Lee, ... Proceedings of the National Academy of Sciences 108 (13), 5378-5383, 2011 | 181 | 2011 |
| The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A … SB Singh, H Jayasuriya, GM Salituro, DL Zink, A Shafiee, B Heimbuch, ... Journal of Natural Products 64 (7), 874-882, 2001 | 128 | 2001 |
| Discovery of Vibegron: A Potent and Selective β3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder SD Edmondson, C Zhu, NF Kar, J Di Salvo, H Nagabukuro, ... Journal of Medicinal Chemistry 59 (2), 609-623, 2016 | 113 | 2016 |
| Discovery of 5-aryloxy-2, 4-thiazolidinediones as potent GPR40 agonists C Zhou, C Tang, E Chang, M Ge, S Lin, E Cline, CP Tan, Y Feng, YP Zhou, ... Bioorganic & Medicinal Chemistry Letters 20 (3), 1298-1301, 2010 | 103 | 2010 |
| Activation of insulin signal transduction pathway and anti-diabetic activity of small molecule insulin receptor activators SA Qureshi, V Ding, Z Li, D Szalkowski, DE Biazzo-Ashnault, D Xie, ... Journal of Biological Chemistry 275 (47), 36590-36595, 2000 | 92 | 2000 |
| Inhibition of human immunodeficiency virus-1 reverse transcriptase activity by rubromycins: competitive interaction at the template. primer site. ME Goldman, GS Salituro, JA Bowen, JM Williamson, DL Zink, WA Schleif, ... Molecular pharmacology 38 (1), 20-25, 1990 | 87 | 1990 |
| Total syntheses of (-)-nocardicins AG: a biogenetic approach GM Salituro, CA Townsend Journal of the American Chemical Society 112 (2), 760-770, 1990 | 87 | 1990 |
| Discovery of a small molecule insulin receptor activator. GM Salituro, F Pelaez, BB Zhang recent progress in hormone research 56, 107-126, 2001 | 80 | 2001 |
| Novel Sesquiterpenoids from the Fermentation of Xylaria persicaria Are Selective Ligands for the NPY Y5 Receptor CJ Smith, NR Morin, GF Bills, AW Dombrowski, GM Salituro, SK Smith, ... The Journal of Organic Chemistry 67 (14), 5001-5004, 2002 | 75 | 2002 |
| Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic … X Chu, SJ Shih, R Shaw, H Hentze, GH Chan, K Owens, S Wang, X Cai, ... Drug Metabolism and Disposition 43 (6), 851-863, 2015 | 65 | 2015 |
| Quinoxapeptins: Novel Chromodepsipeptide Inhibitors of HIV-1 and HIV-2 Reverse Transcriptase I. The Producing Organism and Biological Activity RB LINGHAM, AMYHM Hsu, JA O'BRIEN, JM SIGMUND, M SANCHEZ, ... The Journal of Antibiotics 49 (3), 253-259, 1996 | 61 | 1996 |
| Pharmacological characterization of a novel beta 3 adrenergic agonist, vibegron: evaluation of antimuscarinic receptor selectivity for combination therapy for overactive bladder J Di Salvo, H Nagabukuro, LA Wickham, C Abbadie, JA DeMartino, ... Journal of Pharmacology and Experimental Therapeutics 360 (2), 346-355, 2017 | 60 | 2017 |
| Meridamycin: a novel nonimmunosuppressive FKBP12 ligand from Streptomyces hygroscopicus GM Salituro, DL Zink, A Dahl, J Nielsen, E Wu, L Huang, C Kastner, ... Tetrahedron letters 36 (7), 997-1000, 1995 | 55 | 1995 |
| 3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists SP Walsh, A Severino, C Zhou, J He, GB Liang, CP Tan, J Cao, ... Bioorganic & medicinal chemistry letters 21 (11), 3390-3394, 2011 | 52 | 2011 |
| Discovery of MK-4409, a novel oxazole FAAH inhibitor for the treatment of inflammatory and neuropathic pain HR Chobanian, Y Guo, P Liu, MD Chioda, S Fung, TJ Lanza, L Chang, ... ACS Medicinal Chemistry Letters 5 (6), 717-721, 2014 | 45 | 2014 |
| Development of a Convenient In Vitro Gel Diffusion Model for Predicting the In Vivo Performance of Subcutaneous Parenteral Formulations of Large and Small … DH Leung, Y Kapoor, C Alleyne, E Walsh, A Leithead, B Habulihaz, ... AAPS PharmSciTech 18, 2203-2213, 2017 | 43 | 2017 |
