Brain cell type specific gene expression and co-expression network architectures AT McKenzie, M Wang, ME Hauberg, JF Fullard, A Kozlenkov, A Keenan, ... Scientific reports 8 (1), 8868, 2018 | 362 | 2018 |
The psychencode project S Akbarian, C Liu, JA Knowles, FM Vaccarino, PJ Farnham, GE Crawford, ... Nature neuroscience 18 (12), 1707-1712, 2015 | 336 | 2015 |
A stomatin-domain protein essential for touch sensation in the mouse C Wetzel, J Hu, D Riethmacher, A Benckendorff, L Harder, A Eilers, ... Nature 445 (7124), 206-209, 2007 | 301 | 2007 |
HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity M Kurita, T Holloway, A García-Bea, A Kozlenkov, AK Friedman, ... Nature neuroscience 15 (9), 1245-1254, 2012 | 293 | 2012 |
Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites A Kozlenkov, P Roussos, A Timashpolsky, M Barbu, S Rudchenko, ... Nucleic acids research 42 (1), 109-127, 2014 | 168 | 2014 |
Residues determining the binding specificity of uncompetitive inhibitors to tissue‐nonspecific alkaline phosphatase A Kozlenkov, MH Le Du, P Cuniasse, T Ny, MF Hoylaerts, JL Millán Journal of Bone and Mineral Research 19 (11), 1862-1872, 2004 | 125 | 2004 |
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia JL Moreno, P Miranda-Azpiazu, A García-Bea, J Younkin, M Cui, ... Science signaling 9 (410), ra5-ra5, 2016 | 116 | 2016 |
Substantial DNA methylation differences between two major neuronal subtypes in human brain A Kozlenkov, M Wang, P Roussos, S Rudchenko, M Barbu, M Bibikova, ... Nucleic acids research 44 (6), 2593-2612, 2016 | 111 | 2016 |
The HIV antiretroviral drug efavirenz has LSD-like properties MB Gatch, A Kozlenkov, RQ Huang, W Yang, JD Nguyen, ... Neuropsychopharmacology 38 (12), 2373-2384, 2013 | 105 | 2013 |
Function assignment to conserved residues in mammalian alkaline phosphatases A Kozlenkov, T Manes, MF Hoylaerts, JL Millán Journal of Biological Chemistry 277 (25), 22992-22999, 2002 | 105 | 2002 |
A unique role for DNA (hydroxy) methylation in epigenetic regulation of human inhibitory neurons A Kozlenkov, J Li, P Apontes, YL Hurd, WM Byne, EV Koonin, M Wegner, ... Science advances 4 (9), eaau6190, 2018 | 98 | 2018 |
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects D Ibi, M de la Fuente Revenga, N Kezunovic, C Muguruza, JM Saunders, ... Nature neuroscience 20 (9), 1247-1259, 2017 | 90 | 2017 |
A stomatin dimer modulates the activity of acid‐sensing ion channels J Brand, ESJ Smith, D Schwefel, L Lapatsina, K Poole, D Omerbašić, ... The EMBO journal 31 (17), 3635-3646, 2012 | 88 | 2012 |
Kinetic characterization of hypophosphatasia mutations with physiological substrates S Di Mauro, T Manes, L Hessle, A Kozlenkov, JM Pizauro JR, ... Journal of Bone and Mineral Research 17 (8), 1383-1391, 2002 | 87 | 2002 |
Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum AT Lu, E Hannon, ME Levine, K Hao, EM Crimmins, K Lunnon, ... Nature communications 7 (1), 10561, 2016 | 75 | 2016 |
DNA methylation profiling of human prefrontal cortex neurons in heroin users shows significant difference between genomic contexts of hyper-and hypomethylation and a younger … A Kozlenkov, AE Jaffe, A Timashpolsky, P Apontes, S Rudchenko, ... Genes 8 (6), 152, 2017 | 74 | 2017 |
Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders B Hu, H Won, W Mah, RB Park, B Kassim, K Spiess, A Kozlenkov, ... Nature communications 12 (1), 3968, 2021 | 63 | 2021 |
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons ME Hauberg, J Creus-Muncunill, J Bendl, A Kozlenkov, B Zeng, C Corwin, ... Nature communications 11 (1), 5581, 2020 | 59 | 2020 |
The putative common mechanism for inactivation of alkaline phosphatase isoenzymes OM Poltorak, ES Chukhrai, AA Kozlenkov, MF Chaplin, MD Trevan Journal of Molecular Catalysis B: Enzymatic 7 (1-4), 157-163, 1999 | 52 | 1999 |
Revealing the brain's molecular architecture PsychENCODE Consortium* Science 362 (6420), 1262-1263, 2018 | 50 | 2018 |