Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease DKV Kumar, SH Choi, KJ Washicosky, WA Eimer, S Tucker, J Ghofrani, ... Science translational medicine 8 (340), 340ra72-340ra72, 2016 | 1065 | 2016 |
Alzheimer’s Disease-Associated β-amyloid Is Rapidly Seeded by Herpesviridae to Protect Against Brain Infection WA Eimer, DK Vijaya Kumar, NKN Shanmugam, AS Rodriguez, T Mitchell, ... Neuron 99 (1), 56-63.e3, 2018 | 680 | 2018 |
Phosphorylation of the translation initiation factor eIF2α increases BACE1 levels and promotes amyloidogenesis T O'Connor, KR Sadleir, E Maus, RA Velliquette, J Zhao, SL Cole, ... Neuron 60 (6), 988-1009, 2008 | 502 | 2008 |
Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation WA Eimer, R Vassar Molecular neurodegeneration 8, 1-12, 2013 | 412 | 2013 |
APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease KL Youmans, LM Tai, E Nwabuisi-Heath, L Jungbauer, T Kanekiyo, ... Journal of Biological Chemistry 287 (50), 41774-41786, 2012 | 295 | 2012 |
The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques PC Kandalepas, KR Sadleir, WA Eimer, J Zhao, DA Nicholson, R Vassar Acta neuropathologica 126, 329-352, 2013 | 263 | 2013 |
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody KL Youmans, LM Tai, T Kanekiyo, WB Stine Jr, SC Michon, ... Molecular neurodegeneration 7, 1-14, 2012 | 188 | 2012 |
β-Site Amyloid Precursor Protein (APP)-cleaving Enzyme 1 (BACE1)-deficient Mice Exhibit a Close Homolog of L1 (CHL1) Loss-of-function Phenotype Involving Axon Guidance Defects*♦ B Hitt, SM Riordan, L Kukreja, WA Eimer, TW Rajapaksha, R Vassar Journal of Biological Chemistry 287 (46), 38408-38425, 2012 | 167 | 2012 |
Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level KR Sadleir, WA Eimer, SL Cole, R Vassar Molecular neurodegeneration 10, 1-16, 2015 | 127 | 2015 |
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) AD Proal, MB VanElzakker, S Aleman, K Bach, BP Boribong, M Buggert, ... Nature Immunology 24 (10), 1616-1627, 2023 | 122 | 2023 |
The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb TW Rajapaksha, WA Eimer, TC Bozza, R Vassar Molecular neurodegeneration 6, 1-9, 2011 | 118 | 2011 |
Alzheimer’s disease: the potential therapeutic role of the natural antibiotic amyloid-β peptide DKV Kumar, WA Eimer, RE Tanzi, RD Moir Neurodegenerative disease management 6 (5), 345-348, 2016 | 47 | 2016 |
Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a … KR Sadleir, WA Eimer, RJ Kaufman, P Osten, R Vassar PLoS One 9 (7), e101643, 2014 | 41 | 2014 |
The spectrum of Trp− mutants isolated as 5‐fluoroanthranilate‐resistant clones in Saccharomyces bayanus, S. mikatae and S. paradoxus EW Jones, PB Berget, JM Burnette Iii, C Anderson, D Asafu‐Adjei, ... Yeast 25 (1), 41-46, 2008 | 14 | 2008 |
Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease: Research outline and call for … R Lathe, NM Schultek, BJ Balin, GD Ehrlich, LA Auber, G Perry, ... Alzheimer's & Dementia 19 (11), 5209-5231, 2023 | 12 | 2023 |
Mutant allele-specific CRISPR disruption in DYT1 dystonia fibroblasts restores cell function L Cruz, B György, PS Cheah, BP Kleinstiver, WA Eimer, SP Garcia, ... Molecular Therapy-Nucleic Acids 21, 1-12, 2020 | 11 | 2020 |
Specificity of Toll-like receptor 2 and Dectin-1 signaling in CNS macrophages DKV Kumar, WA Eimer, S Ramakrishnan Journal of Neuroscience 35 (49), 16015-16017, 2015 | 6 | 2015 |
Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) AD Proal, MB VanElzakker, S Aleman, K Bach, BP Boribong, M Buggert, ... Nature Immunology 24 (10), 1778-1778, 2023 | 3 | 2023 |
Erratum to: The Alzheimer’s β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques PC Kandalepas, KR Sadleir, WA Eimer, J Zhao, DA Nicholson, R Vassar Acta Neuropathologica 126 (4), 623, 2013 | 2 | 2013 |
Sensory Dysfunction, Microbial Infections, and Host Responses in Alzheimer's Disease P Bathini, E Brai, BJ Balin, L Bimler, DB Corry, DP Devanand, RL Doty, ... The Journal of infectious diseases 230 (Supplement_2), S150-S164, 2024 | | 2024 |