The neonatal Fc receptor (FcRn): a misnomer? M Pyzik, KMK Sand, JJ Hubbard, JT Andersen, I Sandlie, RS Blumberg Frontiers in immunology 10, 1540, 2019 | 383 | 2019 |
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients JC Holter, SE Pischke, E de Boer, A Lind, S Jenum, AR Holten, K Tonby, ... Proceedings of the National Academy of Sciences 117 (40), 25018-25025, 2020 | 337 | 2020 |
Unraveling the interaction between FcRn and albumin: opportunities for design of albumin-based therapeutics KMK Sand, M Bern, J Nilsen, HT Noordzij, I Sandlie, JT Andersen Frontiers in immunology 5, 682, 2015 | 331 | 2015 |
Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential NM Stapleton, JT Andersen, AM Stemerding, SP Bjarnarson, RC Verheul, ... Nature communications 2 (1), 599, 2011 | 308 | 2011 |
Dependence of antibody-mediated presentation of antigen on FcRn SW Qiao, K Kobayashi, FE Johansen, LM Sollid, JT Andersen, E Milford, ... Proceedings of the National Academy of Sciences 105 (27), 9337-9342, 2008 | 301 | 2008 |
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8− CD11b+ dendritic cells K Baker, SW Qiao, TT Kuo, VG Aveson, B Platzer, JT Andersen, I Sandlie, ... Proceedings of the National Academy of Sciences 108 (24), 9927-9932, 2011 | 230 | 2011 |
Cross-species Binding Analyses of Mouse and Human Neonatal Fc Receptor Show Dramatic Differences in Immunoglobulin G and Albumin Binding 2 JT Andersen, MB Daba, G Berntzen, TE Michaelsen, I Sandlie Journal of Biological Chemistry 285 (7), 4826-4836, 2010 | 215 | 2010 |
Extending half-life by indirect targeting of the neonatal Fc receptor (FcRn) using a minimal albumin binding domain JT Andersen, R Pehrson, V Tolmachev, MB Daba, L Abrahmsén, ... Journal of biological chemistry 286 (7), 5234-5241, 2011 | 214 | 2011 |
Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor JT Andersen, B Dalhus, J Cameron, MB Daba, A Plumridge, L Evans, ... Nature communications 3 (1), 610, 2012 | 207 | 2012 |
The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery M Bern, KMK Sand, J Nilsen, I Sandlie, JT Andersen Journal of Controlled Release 211, 144-162, 2015 | 204 | 2015 |
Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding JT Andersen, B Dalhus, D Viuff, BT Ravn, KS Gunnarsen, A Plumridge, ... Journal of Biological Chemistry 289 (19), 13492-13502, 2014 | 182 | 2014 |
Delivery of an erythropoietin-Fc fusion protein by inhalation in humans through an immunoglobulin transport pathway JA Dumont, AJ Bitonti, D Clark, S Evans, M Pickford, SP Newman Journal of aerosol medicine 18 (3), 294-303, 2005 | 158 | 2005 |
Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies A Shaw, IT Hoffecker, I Smyrlaki, J Rosa, A Grevys, D Bratlie, I Sandlie, ... Nature nanotechnology 14 (2), 184-190, 2019 | 155 | 2019 |
The conserved histidine 166 residue of the human neonatal Fc receptor heavy chain is critical for the pH‐dependent binding to albumin JT Andersen, J Dee Qian, I Sandlie European journal of immunology 36 (11), 3044-3051, 2006 | 146 | 2006 |
Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model H Almåsbak, E Walseng, A Kristian, MR Myhre, EM Suso, LA Munthe, ... Gene therapy 22 (5), 391-403, 2015 | 142 | 2015 |
The versatile MHC class I-related FcRn protects IgG and albumin from degradation: implications for development of new diagnostics and therapeutics JT Andersen, I Sandlie Drug metabolism and pharmacokinetics 24 (4), 318-332, 2009 | 134 | 2009 |
Evaluation of the effects of remdesivir and hydroxychloroquine on viral clearance in COVID-19: a randomized trial A Barratt-Due, IC Olsen, K Nezvalova-Henriksen, T Kåsine, ... Annals of internal medicine 174 (9), 1261-1269, 2021 | 131 | 2021 |
Receptor‐mediated endocytosis of immune complexes in rat liver sinusoidal endothelial cells is mediated by FcγRIIb2 SA Mousavi, M Sporstøl, C Fladeby, R Kjeken, N Barois, T Berg Hepatology 46 (3), 871-884, 2007 | 124 | 2007 |
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn RF Hallstensen, G Bergseth, S Foss, S Jæger, T Gedde-Dahl, J Holt, ... Immunobiology 220 (4), 452-459, 2015 | 122 | 2015 |
TRIM21—from intracellular immunity to therapy S Foss, M Bottermann, A Jonsson, I Sandlie, LC James, JT Andersen Frontiers in Immunology 10, 2049, 2019 | 120 | 2019 |