| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13570* | 2021 |
| A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death Y Suzuki, Y Imai, H Nakayama, K Takahashi, K Takio, R Takahashi Molecular cell 8 (3), 613-621, 2001 | 1515 | 2001 |
| An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin Y Imai, M Soda, H Inoue, N Hattori, Y Mizuno, R Takahashi Cell 105 (7), 891-902, 2001 | 1295 | 2001 |
| Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity Y Imai, M Soda, R Takahashi Journal of Biological Chemistry 275 (46), 35661-35664, 2000 | 952 | 2000 |
| Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin Y Yang, S Gehrke, Y Imai, Z Huang, Y Ouyang, JW Wang, L Yang, ... Proceedings of the National Academy of Sciences 103 (28), 10793-10798, 2006 | 945 | 2006 |
| PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy K Shiba-Fukushima, Y Imai, S Yoshida, Y Ishihama, T Kanao, S Sato, ... Scientific reports 2 (1), 1002, 2012 | 611 | 2012 |
| CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity Y Imai, M Soda, S Hatakeyama, T Akagi, T Hashikawa, KI Nakayama, ... Molecular cell 10 (1), 55-67, 2002 | 608 | 2002 |
| Phosphorylation of 4EBP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila Y Imai, S Gehrke, HQ Wang, R Takahashi, K Hasegawa, E Oota, B Lu The EMBO journal 27 (18), 2432-2443, 2008 | 491 | 2008 |
| Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling Y Yang, S Gehrke, ME Haque, Y Imai, J Kosek, L Yang, MF Beal, ... Proceedings of the National Academy of Sciences 102 (38), 13670-13675, 2005 | 456 | 2005 |
| Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila Y Yang, I Nishimura, Y Imai, R Takahashi, B Lu Neuron 37 (6), 911-924, 2003 | 454 | 2003 |
| Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression S Gehrke, Y Imai, N Sokol, B Lu Nature 466 (7306), 637-641, 2010 | 437 | 2010 |
| Parkinson's disease–associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria S Liu, T Sawada, S Lee, W Yu, G Silverio, P Alapatt, I Millan, A Shen, ... PLoS genetics 8 (3), e1002537, 2012 | 409 | 2012 |
| The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis Y Imai, T Kimura, A Murakami, N Yajima, K Sakamaki, S Yonehara Nature 398 (6730), 777-785, 1999 | 327 | 1999 |
| In vivo evidence of CHIP upregulation attenuating tau aggregation N Sahara, M Murayama, T Mizoroki, M Urushitani, Y Imai, R Takahashi, ... Journal of neurochemistry 94 (5), 1254-1263, 2005 | 242 | 2005 |
| Parkin as a tumor suppressor gene for hepatocellular carcinoma M Fujiwara, H Marusawa, HQ Wang, A Iwai, K Ikeuchi, Y Imai, A Kataoka, ... Oncogene 27 (46), 6002-6011, 2008 | 239 | 2008 |
| Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease K Venderova, G Kabbach, E Abdel-Messih, Y Zhang, RJ Parks, Y Imai, ... Human molecular genetics 18 (22), 4390-4404, 2009 | 207 | 2009 |
| Phosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tethering K Shiba-Fukushima, T Arano, G Matsumoto, T Inoshita, S Yoshida, ... PLoS genetics 10 (12), e1004861, 2014 | 187 | 2014 |
| PaelR is accumulated in Lewy bodies of Parkinson's disease T Murakami, M Shoji, Y Imai, H Inoue, T Kawarabayashi, E Matsubara, ... Annals of Neurology: Official Journal of the American Neurological …, 2004 | 175 | 2004 |
| Loss of Parkinson’s disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c H Meng, C Yamashita, K Shiba-Fukushima, T Inoshita, M Funayama, ... Nature communications 8 (1), 15500, 2017 | 161 | 2017 |
| Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology NN Vaikath, NK Majbour, KE Paleologou, MT Ardah, E van Dam, ... Neurobiology of disease 79, 81-99, 2015 | 152 | 2015 |
