| Conformational variations in an infectious protein determine prion strain differences M Tanaka, P Chien, N Naber, R Cooke, JS Weissman Nature 428 (6980), 323-328, 2004 | 907 | 2004 |
| Emerging principles of conformation-based prion inheritance P Chien, JS Weissman, AH DePace Annual review of biochemistry 73 (1), 617-656, 2004 | 386 | 2004 |
| Segregation of molecules at cell division reveals native protein localization D Landgraf, B Okumus, P Chien, TA Baker, J Paulsson Nature methods 9 (5), 480-482, 2012 | 348 | 2012 |
| Molecular basis of a yeast prion species barrier A Santoso, P Chien, LZ Osherovich, JS Weissman Cell 100 (2), 277-288, 2000 | 325 | 2000 |
| Mechanism of cross-species prion transmission: an infectious conformation compatible withtwo highly divergent yeast prion proteins M Tanaka, P Chien, K Yonekura, JS Weissman Cell 121 (1), 49-62, 2005 | 211 | 2005 |
| Regulatory cohesion of cell cycle and cell differentiation through interlinked phosphorylation and second messenger networks S Abel, P Chien, P Wassmann, T Schirmer, V Kaever, MT Laub, TA Baker, ... Molecular cell 43 (4), 550-560, 2011 | 197 | 2011 |
| Conformational diversity in a yeast prion dictates its seeding specificity P Chien, JS Weissman Nature 410 (6825), 223-227, 2001 | 183 | 2001 |
| Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA K Jonas, J Liu, P Chien, MT Laub Cell 154 (3), 623-636, 2013 | 172 | 2013 |
| Regulated proteolysis in bacteria SA Mahmoud, P Chien Annual review of biochemistry 87 (1), 677-696, 2018 | 146 | 2018 |
| Generation of prion transmission barriers by mutational control of amyloid conformations P Chien, AH DePace, SR Collins, JS Weissman Nature 424 (6951), 948-951, 2003 | 120 | 2003 |
| Direct and adaptor-mediated substrate recognition by an essential AAA+ protease P Chien, BS Perchuk, MT Laub, RT Sauer, TA Baker Proceedings of the National Academy of Sciences 104 (16), 6590-6595, 2007 | 101 | 2007 |
| An adaptor hierarchy regulates proteolysis during a bacterial cell cycle KK Joshi, M Bergé, SK Radhakrishnan, PH Viollier, P Chien Cell 163 (2), 419-431, 2015 | 96 | 2015 |
| Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation S Mukherjee, AC Bree, J Liu, JE Patrick, P Chien, DB Kearns Proceedings of the National Academy of Sciences 112 (1), 250-255, 2015 | 94 | 2015 |
| Identification of ClpP substrates in Caulobacter crescentus reveals a role for regulated proteolysis in bacterial development NH Bhat, RH Vass, PR Stoddard, DK Shin, P Chien Molecular microbiology 88 (6), 1083-1092, 2013 | 86 | 2013 |
| Cell cycle-dependent adaptor complex for ClpXP-mediated proteolysis directly integrates phosphorylation and second messenger signals SC Smith, KK Joshi, JJ Zik, K Trinh, A Kamajaya, P Chien, KR Ryan Proceedings of the National Academy of Sciences 111 (39), 14229-14234, 2014 | 69 | 2014 |
| ClpXP and ClpAP proteolytic activity on divisome substrates is differentially regulated following the Caulobacter asymmetric cell division B Williams, N Bhat, P Chien, L Shapiro Molecular microbiology 93 (5), 853-866, 2014 | 67 | 2014 |
| Regulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus KG Gora, A Cantin, M Wohlever, KK Joshi, BS Perchuk, P Chien, MT Laub Molecular microbiology 87 (6), 1277-1289, 2013 | 66 | 2013 |
| Challenges and dreams: physics of weak interactions essential to life P Chien, LM Gierasch Molecular biology of the cell 25 (22), 3474-3477, 2014 | 64 | 2014 |
| A phosphosignaling adaptor primes the AAA+ protease ClpXP to drive cell cycle-regulated proteolysis J Lau, L Hernandez-Alicea, RH Vass, P Chien Molecular cell 59 (1), 104-116, 2015 | 53 | 2015 |
| Sinorhizobium meliloti CpdR1 is critical for co‐ordinating cell cycle progression and the symbiotic chronic infection H Kobayashi, NJ De Nisco, P Chien, LA Simmons, GC Walker Molecular microbiology 73 (4), 586-600, 2009 | 53 | 2009 |
