| Development of halogenase enzymes for use in synthesis J Latham, E Brandenburger, SA Shepherd, BRK Menon, J Micklefield Chemical Reviews 118 (1), 232-269, 2018 | 315 | 2018 |
| Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C–H activation J Latham, JM Henry, HH Sharif, BRK Menon, SA Shepherd, MF Greaney, ... Nature communications 7 (1), 11873, 2016 | 160 | 2016 |
| Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes SA Shepherd, C Karthikeyan, J Latham, AW Struck, ML Thompson, ... Chemical science 6 (6), 3454-3460, 2015 | 125 | 2015 |
| A structure‐guided switch in the regioselectivity of a tryptophan halogenase SA Shepherd, BRK Menon, H Fisk, AW Struck, C Levy, D Leys, ... ChemBioChem 17 (9), 821-824, 2016 | 93 | 2016 |
| Structure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymes BRK Menon, J Latham, MS Dunstan, E Brandenburger, U Klemstein, ... Organic & Biomolecular Chemistry 14 (39), 9354-9361, 2016 | 74 | 2016 |
| A microbial platform for renewable propane synthesis based on a fermentative butanol pathway N Menon, A Pásztor, BRK Menon, P Kallio, K Fisher, MK Akhtar, D Leys, ... Biotechnology for biofuels 8, 1-12, 2015 | 72 | 2015 |
| RadH: a versatile halogenase for integration into synthetic pathways BRK Menon, E Brandenburger, HH Sharif, U Klemstein, SA Shepherd, ... Angewandte Chemie International Edition 56 (39), 11841-11845, 2017 | 67 | 2017 |
| Assembling a plug-and-play production line for combinatorial biosynthesis of aromatic polyketides in Escherichia coli M Cummings, AD Peters, GFS Whitehead, BRK Menon, J Micklefield, ... PLoS biology 17 (7), e3000347, 2019 | 45 | 2019 |
| Cryogenic and laser photoexcitation studies identify multiple roles for active site residues in the light-driven enzyme protochlorophyllide oxidoreductase BRK Menon, JP Waltho, NS Scrutton, DJ Heyes Journal of Biological Chemistry 284 (27), 18160-18166, 2009 | 45 | 2009 |
| Mutagenesis alters the catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase BRK Menon, PA Davison, CN Hunter, NS Scrutton, DJ Heyes Journal of Biological Chemistry 285 (3), 2113-2119, 2010 | 40 | 2010 |
| Conformational Events during Ternary Enzyme− Substrate Complex Formation Are Rate Limiting in the Catalytic Cycle of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase DJ Heyes, BRK Menon, M Sakuma, NS Scrutton Biochemistry 47 (41), 10991-10998, 2008 | 40 | 2008 |
| Structure and Biocatalytic Scope of Coclaurine N‐Methyltransferase MR Bennett, ML Thompson, SA Shepherd, MS Dunstan, AJ Herbert, ... Angewandte Chemie International Edition 57 (33), 10600-10604, 2018 | 38 | 2018 |
| Halogenases for biosynthetic pathway engineering: Toward new routes to naturals and non-naturals BRK Menon, D Richmond, N Menon Catalysis Reviews 64 (3), 533-591, 2022 | 34 | 2022 |
| The missing colours of chemistry BRK Menon Nature Chemistry 13 (2), 101-106, 2021 | 32 | 2021 |
| Halonium-induced polyene cyclizations ACA D’Hollander, L Peilleron, TD Grayfer, K Cariou Synthesis 51 (08), 1753-1769, 2019 | 29 | 2019 |
| Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR) BRK Menon, SJO Hardman, NS Scrutton, DJ Heyes Journal of Photochemistry and Photobiology B: Biology 161, 236-243, 2016 | 25 | 2016 |
| An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme M Ortmayer, P Lafite, BRK Menon, T Tralau, K Fisher, L Denkhaus, ... Nature 539 (7630), 593-597, 2016 | 23 | 2016 |
| Versatile and Facile One-Pot Biosynthesis for Amides and Carboxylic Acids in E. coli by Engineering Auxin Pathways of Plant Microbiomes N Menon, D Richmond, MR Rahman, BRK Menon ACS Catalysis 12 (4), 2309-2319, 2022 | 9 | 2022 |
| A conformational sampling model for radical catalysis in pyridoxal phosphate-and cobalamin-dependent enzymes BRK Menon, K Fisher, SEJ Rigby, NS Scrutton, D Leys Journal of Biological Chemistry 289 (49), 34161-34174, 2014 | 7 | 2014 |
| Reprogramming assembly lines BRK Menon, M Jenner Nature Chemistry 10 (3), 245-247, 2018 | 3 | 2018 |
David LeysProfessor in Structural Biology, Manchester University在 manchester.ac.uk 的电子邮件经过验证
