| Characterization and comparison of ATF and TFF in stirred bioreactors for continuous mammalian cell culture processes DJ Karst, E Serra, TK Villiger, M Soos, M Morbidelli Biochemical Engineering Journal 110, 17-26, 2016 | 145 | 2016 |
| Evaluating the impact of cell culture process parameters on monoclonal antibody N-glycosylation M Ivarsson, TK Villiger, M Morbidelli, M Soos Journal of biotechnology 188, 88-96, 2014 | 141 | 2014 |
| Development of a scale-down model of hydrodynamic stress to study the performance of an industrial CHO cell line under simulated production scale bioreactor conditions JB Sieck, T Cordes, WE Budach, MH Rhiel, Z Suemeghy, C Leist, ... Journal of biotechnology 164 (1), 41-49, 2013 | 102 | 2013 |
| Experimental and CFD physical characterization of animal cell bioreactors: from micro-to production scale TK Villiger, B Neunstoecklin, DJ Karst, E Lucas, M Stettler, H Broly, ... Biochemical engineering journal 131, 84-94, 2018 | 84 | 2018 |
| Modulation and modeling of monoclonal antibody N‐linked glycosylation in mammalian cell perfusion reactors DJ Karst, E Scibona, E Serra, JM Bielser, J Souquet, M Stettler, H Broly, ... Biotechnology and Bioengineering 114 (9), 1978-1990, 2017 | 77 | 2017 |
| Analysis of site-specific N-glycan remodeling in the endoplasmic reticulum and the Golgi I Hang, C Lin, OC Grant, S Fleurkens, TK Villiger, M Soos, M Morbidelli, ... Glycobiology 25 (12), 1335-1349, 2015 | 77 | 2015 |
| Controlling the time evolution of mAb N‐linked glycosylation‐Part II: Model‐based predictions TK Villiger, E Scibona, M Stettler, H Broly, M Morbidelli, M Soos Biotechnology progress 32 (5), 1135-1148, 2016 | 59 | 2016 |
| Controlling the time evolution of mAb N‐linked glycosylation, Part I: Microbioreactor experiments TK Villiger, A Roulet, A Périlleux, M Stettler, H Broly, M Morbidelli, M Soos Biotechnology progress 32 (5), 1123-1134, 2016 | 47 | 2016 |
| Influence of protein/glycan interaction on site‐specific glycan heterogeneity ME Losfeld, E Scibona, CW Lin, TK Villiger, R Gauss, M Morbidelli, ... The FASEB Journal 31 (10), 4623-4635, 2017 | 43 | 2017 |
| Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster ovary fed-batch cultures S Hutter, TK Villiger, D Brühlmann, M Stettler, H Broly, M Soos, ... Metabolic engineering 43, 9-20, 2017 | 43 | 2017 |
| High-throughput profiling of nucleotides and nucleotide sugars to evaluate their impact on antibody N-glycosylation TK Villiger, RF Steinhoff, M Ivarsson, T Solacroup, M Stettler, H Broly, ... Journal of biotechnology 229, 3-12, 2016 | 42 | 2016 |
| Adaptation for survival: Phenotype and transcriptome response of CHO cells to elevated stress induced by agitation and sparging JB Sieck, WE Budach, Z Suemeghy, C Leist, TK Villiger, M Morbidelli, ... Journal of biotechnology 189, 94-103, 2014 | 41 | 2014 |
| Experimental determination of maximum effective hydrodynamic stress in multiphase flow using shear sensitive aggregates TK Villiger, M Morbidelli, M Soos AIChE Journal 61 (5), 1735-1744, 2015 | 35 | 2015 |
| Pilot-scale verification of maximum tolerable hydrodynamic stress for mammalian cell culture B Neunstoecklin, TK Villiger, E Lucas, M Stettler, H Broly, M Morbidelli, ... Applied microbiology and biotechnology 100, 3489-3498, 2016 | 28 | 2016 |
| High‐throughput nucleoside phosphate monitoring in mammalian cell fed‐batch cultivation using quantitative matrix‐assisted laser desorption/ionization time‐of‐flight mass … RF Steinhoff, M Ivarsson, T Habicher, TK Villiger, J Boertz, J Krismer, ... Biotechnology journal 10 (1), 190-198, 2015 | 18 | 2015 |
| Proteomic analysis of micro-scale bioreactors as scale-down model for a mAb producing CHO industrial fed-batch platform V Bertrand, S Vogg, TK Villiger, M Stettler, H Broly, M Soos, M Morbidelli Journal of biotechnology 279, 27-36, 2018 | 16 | 2018 |
| Advancing Raman model calibration for perfusion bioprocesses using spiked harvest libraries P Romann, J Kolar, D Tobler, C Herwig, JM Bielser, TK Villiger Biotechnology Journal 17 (11), 2200184, 2022 | 9 | 2022 |
| Modeling of the Degradation of Poly(ethylene glycol)-co-(lactic acid)-dimethacrylate Hydrogels VEG Diederich, T Villiger, G Storti, M Lattuada Macromolecules 50 (14), 5527-5538, 2017 | 9 | 2017 |
| Characterization and comparison of ATF and TFF in stirred bioreactors for the continuous production of therapeutic proteins DJ Karst, E Serra, TK Villiger, M Soos, M Morbidelli Biochemical Engineering Journal 110, 17-26, 2016 | 7 | 2016 |
| Maximizing yield of perfusion cell culture processes: Evaluation and scale-up of continuous bleed recycling P Romann, J Kolar, L Chappuis, C Herwig, TK Villiger, JM Bielser Biochemical Engineering Journal 193, 108873, 2023 | 5 | 2023 |
Miroslav SoosUCT Prague在 vscht.cz 的电子邮件经过验证
