Erythroferrone inhibits the induction of hepcidin by BMP6 J Arezes, N Foy, K McHugh, A Sawant, D Quinkert, V Terraube, A Brinth, ... Blood, The Journal of the American Society of Hematology 132 (14), 1473-1477, 2018 | 259 | 2018 |
KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis I Wong-Baeza, A Ridley, J Shaw, H Hatano, O Rysnik, K McHugh, C Piper, ... The Journal of Immunology 190 (7), 3216-3224, 2013 | 119 | 2013 |
The link between HLA-B27 and SpA—new ideas on an old problem K McHugh, P Bowness Rheumatology 51 (9), 1529-1539, 2012 | 91 | 2012 |
Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA–B27 L Chen, R Fischer, Y Peng, E Reeves, K McHugh, N Ternette, T Hanke, ... Arthritis & rheumatology 66 (2), 284-294, 2014 | 88 | 2014 |
Ankylosing spondylitis monocytes show upregulation of proteins involved in inflammation and the ubiquitin proteasome pathway C Wright, M Edelmann, S Kollnberger, H Kramer, S McGowan, K McHugh, ... Annals of the Rheumatic Diseases 68 (10), 1626-1632, 2009 | 81 | 2009 |
Regulation of hepcidin by erythropoiesis: the story so far SR Pasricha, K McHugh, H Drakesmith Annual review of nutrition 36, 417-434, 2016 | 71 | 2016 |
Inhibiting HLA–B27 homodimer–driven immune cell inflammation in spondylarthritis SK Payeli, S Kollnberger, O Marroquin Belaunzaran, M Thiel, K McHugh, ... Arthritis & Rheumatism 64 (10), 3139-3149, 2012 | 70 | 2012 |
HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I J Giles, J Shaw, C Piper, I Wong-Baeza, K McHugh, A Ridley, D Li, ... The Journal of Immunology 188 (12), 6184-6193, 2012 | 66 | 2012 |
Hepcidin is regulated by promoter-associated histone acetylation and HDAC3 SR Pasricha, PJ Lim, TL Duarte, C Casu, D Oosterhuis, ... Nature communications 8 (1), 1-15, 2017 | 63 | 2017 |
The arthritis-associated HLA-B* 27: 05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B* 27: 09 A Cauli, J Shaw, J Giles, H Hatano, O Rysnik, S Payeli, K McHugh, ... Rheumatology 52 (11), 1952-1962, 2013 | 62 | 2013 |
Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia J Arezes, N Foy, K McHugh, D Quinkert, S Benard, A Sawant, JN Frost, ... Blood 135 (8), 547-557, 2020 | 58 | 2020 |
Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replication AN Antoniou, I Lenart, J Kriston-Vizi, T Iwawaki, M Turmaine, K McHugh, ... Annals of the rheumatic diseases 78 (1), 74-82, 2019 | 53 | 2019 |
Human basigin (CD147) does not directly interact with SARS-CoV-2 spike glycoprotein RJ Ragotte, D Pulido, FR Donnellan, ML Hill, G Gorini, H Davies, J Brun, ... Msphere 6 (4), e00647-21, 2021 | 42 | 2021 |
Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply K McHugh, O Rysnik, S Kollnberger, J Shaw, L Utriainen, MH Al-Mossawi, ... Annals of the rheumatic diseases 73 (4), 763-770, 2014 | 33 | 2014 |
Non-conventional forms of HLA-B27 are expressed in spondyloarthritis joints and gut tissue O Rysnik, K McHugh, L van Duivenvoorde, M van Tok, G Guggino, ... Journal of autoimmunity 70, 12-21, 2016 | 29 | 2016 |
Polymorphisms in the F Pocket of HLA–B27 Subtypes Strongly Affect Assembly, Chaperone Interactions, and Heavy‐Chain Misfolding DB Guiliano, H North, E Panayoitou, EC Campbell, K McHugh, ... Arthritis & rheumatology 69 (3), 610-621, 2017 | 26 | 2017 |
Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly AM Minassian, Y Themistocleous, SE Silk, JR Barrett, A Kemp, D Quinkert, ... JCI insight 6 (23), 2021 | 22 | 2021 |
Clinical trials on MDR reversal agents K McHugh, R Callaghan Multidrug Resistance: Biological and Pharmaceutical Advances in Antitumour …, 2008 | 15 | 2008 |
Data showing non-conventional HLA-B27 expression in axial joints and gut tissue from B27 transgenic rats, and in frozen and paraffin-fixed synovial SpA tissue O Rysnik, K McHugh, L van Duivenvoorde, M van Tok, J Taurog, ... Data in brief 9, 100-111, 2016 | 4 | 2016 |
Intrinsic folding properties of the HLA-B27 heavy chain revealed by single chain trimer versions of peptide-loaded class I Major Histocompatibility Complex molecules I Lenart, LH Truong, DD Nguyen, O Rasiukienė, E Tsao, J Armstrong, ... Frontiers in Immunology, 2022 | 3 | 2022 |