PHGDH heterogeneity potentiates cancer cell dissemination and metastasis M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ... Nature 605 (7911), 747-753, 2022 | 104 | 2022 |
In vivo evidence for serine biosynthesis-defined sensitivity of lung metastasis, but not of primary breast tumors, to mTORC1 inhibition G Rinaldi, E Pranzini, J Van Elsen, D Broekaert, CM Funk, M Planque, ... Molecular cell 81 (2), 386-397. e7, 2021 | 76 | 2021 |
Stable isotopes for tracing mammalian-cell metabolism in vivo J Fernández-García, P Altea-Manzano, E Pranzini, SM Fendt Trends in biochemical sciences 45 (3), 185-201, 2020 | 74 | 2020 |
Nutrient metabolism and cancer in the in vivo context: a metabolic game of give and take P Altea‐Manzano, AM Cuadros, LA Broadfield, SM Fendt EMBO reports 21 (10), e50635, 2020 | 67 | 2020 |
Number of nanoparticles per cell through a spectrophotometric method-a key parameter to assess nanoparticle-based cellular assays JD Unciti-Broceta, V Cano-Cortés, P Altea-Manzano, S Pernagallo, ... Scientific reports 5 (1), 10091, 2015 | 54 | 2015 |
A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling P Altea-Manzano, G Doglioni, Y Liu, AM Cuadros, E Nolan, ... Nature cancer 4 (3), 344-364, 2023 | 43 | 2023 |
CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation J Fernandez-Garcia, F Franco, S Parik, P Altea-Manzano, AA Pane, ... Cell Reports 41 (7), 2022 | 19 | 2022 |
Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells P Altea-Manzano, A Vandekeere, J Edwards-Hicks, M Roldan, ... Molecular Cell 82 (23), 4537-4547. e7, 2022 | 16 | 2022 |
Tracking cell proliferation using a nanotechnology-based approach P Altea-Manzano, JD Unciti-Broceta, V Cano-Cortes, MP Ruiz-Blas, ... Nanomedicine 12 (13), 1591-1605, 2017 | 12 | 2017 |
Microstructural and strength changes in trabecular bone in elderly patients with type 2 diabetes mellitus M Giner, C Miranda, MA Vázquez-Gámez, P Altea-Manzano, MJ Miranda, ... Diagnostics 11 (3), 577, 2021 | 10 | 2021 |
An effective polymeric nanocarrier that allows for active targeting and selective drug delivery in cell coculture systems MV Cano-Cortes, P Altea-Manzano, JA Laz-Ruiz, JD Unciti-Broceta, ... Nanoscale 13 (6), 3500-3511, 2021 | 6 | 2021 |
Analyzing the metabolism of metastases in mice P Altea-Manzano, D Broekaert, JAG Duarte, J Fernández-García, ... Metabolic Flux Analysis in Eukaryotic Cells: Methods and Protocols, 93-118, 2020 | 5 | 2020 |
Serum methylmalonic acid concentrations at breast cancer diagnosis significantly correlate with clinical frailty Q Wu, S Hatse, C Kenis, J Fernández-García, P Altea-Manzano, J Billen, ... GeroScience 46 (2), 1489-1498, 2024 | 4 | 2024 |
Palmitic acid: Enabling the tumor’s nerves HF Alkan, P Altea-Manzano, SM Fendt Cell Metabolism 34 (1), 7-9, 2022 | 4 | 2022 |
In vivo CRISPR screen defines Slc25a37 as an organ-specific regulator of antioxidant metabolism in metastasis AM Cuadros, J Fernández-Garcia, M Planque, P Altea-Manzano, ... Biorxiv, 2022.09. 03.506468, 2022 | 3 | 2022 |
Metabolite-derived protein modifications modulating oncogenic signaling Y Liu, A Vandekeere, M Xu, SM Fendt, P Altea-Manzano Frontiers in Oncology 12, 988626, 2022 | 2 | 2022 |
Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ... Nature 609 (7927), E8, 2022 | 1 | 2022 |
Metabolic Rewiring During Metastasis: The Interplay Between the Environment and the Host A Vandekeere, S El Kharraz, P Altea-Manzano, SM Fendt Annual Review of Cancer Biology 8 (1), 269-290, 2024 | | 2024 |
Aging-accumulated methylmalonic acid serum levels at breast cancer diagnosis are not associated with distant metastases Q Wu, S Hatse, C Kenis, J Fernández-García, P Altea-Manzano, J Billen, ... Breast Cancer Research and Treatment 205 (3), 555-565, 2024 | | 2024 |
The primary tumor-derived extracellular vesicles activate lung alveolar type II cells to prime the pre-metastatic niche X Liu, Y Panina, P Altea Manzano, S El Kharraz, M Yuneva, SM Fendt Tumor Heterogeneity, Plasticity and Therapy (2nd edition), Date: 2023/10/03 …, 2023 | | 2023 |