| CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones FA Harding, JG McArthur, JA Gross, DH Raulet, JP Allison Nature 356 (6370), 607-609, 1992 | 2219 | 1992 |
| Antigen-specific human antibodies from mice comprising four distinct genetic modifications N Lonberg, LD Taylor, FA Harding, M Trounstine, KM Higgins, ... Nature 368 (6474), 856-859, 1994 | 1162 | 1994 |
| High-avidity human IgGκ monoclonal antibodies from a novel strain of minilocus transgenic mice DM Fishwild, SL O'Donnell, T Bengoechea, DV Hudson, F Harding, ... Nature biotechnology 14 (7), 845-851, 1996 | 854 | 1996 |
| The immunogenicity of humanized and fully human antibodies: residual immunogenicity resides in the CDR regions FA Harding, MM Stickler, J Razo, R DuBridge MAbs 2 (3), 256-265, 2010 | 790 | 2010 |
| CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help. FA Harding, JP Allison The Journal of experimental medicine 177 (6), 1791-1796, 1993 | 370 | 1993 |
| Class switching in human immunoglobulin transgenic mice. FA Harding, N Lonberg Annals of the New York Academy of Sciences 764, 536-546, 1995 | 246 | 1995 |
| Two distinct immunoglobulin heavy chain isotypes in a primitive, cartilaginous fish, Raja erinacea FA Harding, CT Amemiya, RT Litman, N Cohen, GW Litman Nucleic acids research 18 (21), 6369-6376, 1990 | 108 | 1990 |
| Elimination of an immunodominant CD4+ T cell epitope in human IFN-β does not result in an in vivo response directed at the subdominant epitope VP Yeung, J Chang, J Miller, C Barnett, M Stickler, FA Harding The Journal of Immunology 172 (11), 6658-6665, 2004 | 97 | 2004 |
| Immunoglobulin heavy chain gene organization and complexity in the skate, Raja erinacea FA Harding, N Cohen, GW Litman Nucleic acids research 18 (4), 1015-1020, 1990 | 92 | 1990 |
| Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450 AG Braun, FA Harding, SL Weinreb Toxicology and applied pharmacology 82 (1), 175-179, 1986 | 88 | 1986 |
| A β-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy FA Harding, AD Liu, M Stickler, OJ Razo, R Chin, N Faravashi, W Viola, ... Molecular cancer therapeutics 4 (11), 1791-1800, 2005 | 83 | 2005 |
| Fc variants FA Harding, PR Hinton, M Xiong, OJ Razo, S Ye US Patent App. 14/214,146, 2014 | 75 | 2014 |
| Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins DA Estell, FA Harding US Patent 6,218,165, 2001 | 48 | 2001 |
| An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy S Chan, N Belmar, S Ho, B Rogers, M Stickler, M Graham, E Lee, N Tran, ... Nature cancer 3 (3), 337-354, 2022 | 47 | 2022 |
| Fluid mechanical stress and the platelet HL Goldsmith, SSK Yu, J Marlow Thrombosis and Haemostasis 34 (04), 032-041, 1975 | 47 | 1975 |
| CD4+ T-cell epitope determination using unexposed human donor peripheral blood mononuclear cells MM Stickler, DA Estell, FA Harding Journal of Immunotherapy 23 (6), 654-660, 2000 | 46 | 2000 |
| Anti-PD-1 antibodies and their uses DEH Afar, FA Harding, J Samayoa US Patent 9,914,783, 2018 | 43 | 2018 |
| Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins DA Estell, FA Harding US Patent 6,835,550, 2004 | 43 | 2004 |
| The HLA-DR2 haplotype is associated with an increased proliferative response to the immunodominant CD4+ T-cell epitope in human interferon-β M Stickler, AM Valdes, W Gebel, OJ Razo, N Faravashi, R Chin, ... Genes & Immunity 5 (1), 1-7, 2004 | 41 | 2004 |
| Human population-based identification of CD4+ T-cell peptide epitope determinants M Stickler, R Chin, N Faravashi, W Gebel, OJ Razo, N Rochanayon, ... Journal of immunological methods 281 (1-2), 95-108, 2003 | 41 | 2003 |
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