Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype B Falini, C Mecucci, E Tiacci, M Alcalay, R Rosati, L Pasqualucci, ... New England Journal of Medicine 352 (3), 254-266, 2005 | 2307 | 2005 |
The acute promyelocytic leukemia-specific PML-RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells F Grignani, PF Ferrucci, U Testa, G Talamo, M Fagioli, M Alcalay, ... Cell 74 (3), 423-431, 1993 | 728 | 1993 |
Acute promyelocytic leukemia: from genetics to treatment F Grignani, M Fagioli, M Alcalay, L Longo, PP Pandolfi, E Donti, A Biondi, ... | 669 | 1994 |
A PMLRARα transgene initiates murine acute promyelocytic leukemia D Brown, S Kogan, E Lagasse, I Weissman, M Alcalay, PG Pelicci, ... Proceedings of the National Academy of Sciences 94 (6), 2551-2556, 1997 | 595 | 1997 |
Acute myeloid leukemia bearing cytoplasmic nucleophosmin (NPMc+ AML) shows a distinct gene expression profile characterized by up-regulation of genes … M Alcalay, E Tiacci, R Bergomas, B Bigerna, E Venturini, SP Minardi, ... Blood 106 (3), 899-902, 2005 | 417 | 2005 |
Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties. PP Pandolfi, F Grignani, M Alcalay, A Mencarelli, A Biondi, F LoCoco, ... Oncogene 6 (7), 1285-1292, 1991 | 396 | 1991 |
Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells A Viale, F De Franco, A Orleth, V Cambiaghi, V Giuliani, D Bossi, ... Nature 457 (7225), 51-56, 2009 | 389 | 2009 |
Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic … PP Pandolfi, M Alcalay, M Fagioli, D Zangrilli, A Mencarelli, D Diverio, ... The EMBO journal 11 (4), 1397-1407, 1992 | 336 | 1992 |
Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus. M Alcalay, D Zangrilli, PP Pandolfi, L Longo, A Mencarelli, ... Proceedings of the National Academy of Sciences 88 (5), 1977-1981, 1991 | 336 | 1991 |
Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair M Alcalay, N Meani, V Gelmetti, A Fantozzi, M Fagioli, A Orleth, ... The Journal of clinical investigation 112 (11), 1751-1761, 2003 | 333 | 2003 |
Role for histone deacetylase 1 in human tumor cell proliferation S Senese, K Zaragoza, S Minardi, I Muradore, S Ronzoni, A Passafaro, ... Molecular and cellular biology 27 (13), 4784-4795, 2007 | 319 | 2007 |
Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases E Colombo, M Alcalay, PG Pelicci Oncogene 30 (23), 2595-2609, 2011 | 250 | 2011 |
Rearrangements and aberrant expression of the RARα gene in acute promyelocytic leukemias L Longo, PP Pandolfi, A Biondi, A Rambaldi, A Mencarelli, F Lo Coco, ... Journal of Experimental Medicine 172, 1571-1575, 1990 | 242 | 1990 |
The promyelocytic leukemia gene product (PML) forms stable complexes with the retinoblastoma protein M Alcalay, L Tomassoni, E Colombo, S Stoldt, F Grignani, M Fagioli, ... Molecular and cellular biology 18 (2), 1084-1093, 1998 | 238 | 1998 |
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia B Falini, MP Martelli, N Bolli, R Bonasso, E Ghia, MT Pallotta, D Diverio, ... Blood 108 (6), 1999-2005, 2006 | 220 | 2006 |
Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms. M Fagioli, M Alcalay, PP Pandolfi, L Venturini, A Mencarelli, A Simeone, ... Oncogene 7 (6), 1083-1091, 1992 | 220 | 1992 |
Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute promyelocytic leukemia by polymerase chain reaction A Biondi, A Rambaldi, PP Pandolfi, V Rossi, G Giudici, M Alcalay, ... | 215 | 1992 |
Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant E Colombo, P Martinelli, R Zamponi, DC Shing, P Bonetti, L Luzi, ... Cancer research 66 (6), 3044-3050, 2006 | 203 | 2006 |
Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia. M Alcalay, D Zangrilli, M Fagioli, PP Pandolfi, A Mencarelli, F Lo Coco, ... Proceedings of the National Academy of Sciences 89 (11), 4840-4844, 1992 | 188 | 1992 |
Family expansion and gene rearrangements contributed to the functional specialization of PRDM genes in vertebrates I Fumasoni, N Meani, D Rambaldi, G Scafetta, M Alcalay, FD Ciccarelli BMC evolutionary biology 7, 1-11, 2007 | 177 | 2007 |