| Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice E Rodriguez-Lebron, EM Denovan-Wright, K Nash, AS Lewin, RJ Mandel Molecular therapy 12 (4), 618-633, 2005 | 331 | 2005 |
| In vivo RNAi-mediated α-synuclein silencing induces nigrostriatal degeneration OS Gorbatyuk, S Li, K Nash, M Gorbatyuk, AS Lewin, LF Sullivan, ... Molecular Therapy 18 (8), 1450-1457, 2010 | 238 | 2010 |
| Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration B Grimmig, SH Kim, K Nash, PC Bickford, R Douglas Shytle Geroscience 39, 19-32, 2017 | 190 | 2017 |
| Successful production of pseudotyped rAAV vectors using a modified baculovirus expression system E Kohlbrenner, G Aslanidi, K Nash, S Shklyaev, M Campbell-Thompson, ... Molecular therapy 12 (6), 1217-1225, 2005 | 168 | 2005 |
| Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders RJ Mandel, FP Manfredsson, KD Foust, A Rising, S Reimsnider, K Nash, ... Molecular Therapy 13 (3), 463-483, 2006 | 159 | 2006 |
| Recombinant adeno-associated viral vectors in the nervous system C Burger, K Nash, RJ Mandel Human gene therapy 16 (7), 781-791, 2005 | 148 | 2005 |
| Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice L Lebson, K Nash, S Kamath, D Herber, N Carty, DC Lee, Q Li, ... Journal of Neuroscience 30 (29), 9651-9658, 2010 | 147 | 2010 |
| Heparin binding induces conformational changes in Adeno-associated virus serotype 2 HC Levy, VD Bowman, L Govindasamy, R McKenna, K Nash, ... Journal of structural biology 165 (3), 146-156, 2009 | 145 | 2009 |
| The soluble isoform of CX3CL1 is necessary for neuroprotection in a mouse model of Parkinson's disease JM Morganti, KR Nash, BA Grimmig, S Ranjit, B Small, PC Bickford, ... Journal of Neuroscience 32 (42), 14592-14601, 2012 | 138 | 2012 |
| Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition ML Selenica, L Benner, SB Housley, B Manchec, DC Lee, KR Nash, ... Alzheimer's research & therapy 6, 1-12, 2014 | 137 | 2014 |
| Aging enhances classical activation but mitigates alternative activation in the central nervous system DC Lee, CR Ruiz, L Lebson, MLB Selenica, J Rizer, JB Hunt Jr, R Rojiani, ... Neurobiology of aging 34 (6), 1610-1620, 2013 | 130 | 2013 |
| Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome JL Daily, K Nash, U Jinwal, T Golde, J Rogers, MM Peters, RD Burdine, ... PloS one 6 (12), e27221, 2011 | 127 | 2011 |
| Fractalkine overexpression suppresses tau pathology in a mouse model of tauopathy KR Nash, DC Lee, JB Hunt Jr, JM Morganti, ML Selenica, P Moran, ... Neurobiology of aging 34 (6), 1540-1548, 2013 | 120 | 2013 |
| Neuroinflammation and fractalkine signaling in Alzheimer’s disease DJ Finneran, KR Nash Journal of neuroinflammation 16 (1), 30, 2019 | 117 | 2019 |
| Production of pseudotyped recombinant AAV virions RO Snyder, S Zolotukhin, Y Sakai, BJ Byrne, MR Potter, I Zolotukhin, ... US Patent 7,094,604, 2006 | 105 | 2006 |
| Diverse activation of microglia by chemokine (CC motif) ligand 2 overexpression in brain MLB Selenica, JA Alvarez, KR Nash, DC Lee, C Cao, X Lin, P Reid, ... Journal of neuroinflammation 10, 1-17, 2013 | 103 | 2013 |
| Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins K Nash, W Chen, N Muzyczka Journal of virology 82 (3), 1458-1464, 2008 | 103 | 2008 |
| Identification of cellular proteins that interact with the adeno-associated virus rep protein K Nash, W Chen, M Salganik, N Muzyczka Journal of virology 83 (1), 454-469, 2009 | 99 | 2009 |
| Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain N Carty, D Lee, C Dickey, C Ceballos-Diaz, K Jansen-West, TE Golde, ... Journal of neuroscience methods 194 (1), 144-153, 2010 | 91 | 2010 |
| Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat model of Parkinson’s … M Shahaduzzaman, K Nash, C Hudson, M Sharif, B Grimmig, X Lin, G Bai, ... PloS one 10 (2), e0116841, 2015 | 90 | 2015 |
