Ebola virus VP24 targets a unique NLS binding site on karyopherin alpha 5 to selectively compete with nuclear import of phosphorylated STAT1 W Xu, MR Edwards, DM Borek, AR Feagins, A Mittal, JB Alinger, KN Berry, ... Cell host & microbe 16 (2), 187-200, 2014 | 255 | 2014 |
Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice W He, CJ Chen, CE Mullarkey, JR Hamilton, CK Wong, PE Leon, ... Nature communications 8 (1), 846, 2017 | 165 | 2017 |
Targeting viral proteostasis limits influenza virus, HIV, and dengue virus infection NS Heaton, N Moshkina, R Fenouil, TJ Gardner, S Aguirre, PS Shah, ... Immunity 44 (1), 46-58, 2016 | 130 | 2016 |
Experimental evidence for interspecific directional selection on moth pheromone communication AT Groot, JL Horovitz, J Hamilton, RG Santangelo, C Schal, F Gould Proceedings of the National Academy of Sciences 103 (15), 5858-5863, 2006 | 123 | 2006 |
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering JR Hamilton, CA Tsuchida, DN Nguyen, BR Shy, ER McGarrigle, ... Cell reports 35 (9), 2021 | 111 | 2021 |
Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity JR Hamilton, D Sachs, JK Lim, RA Langlois, P Palese, NS Heaton Proceedings of the National Academy of Sciences 113 (14), 3861-3866, 2016 | 56 | 2016 |
A Recombinant Antibody-Expressing Influenza Virus Delays Tumor Growth in a Mouse Model JR Hamilton, G Vijayakumar, P Palese Cell Reports 22 (1), 1-7, 2018 | 55 | 2018 |
QTL analysis of sex pheromone blend differences between two closely related moths: insights into divergence in biosynthetic pathways AT Groot, ML Estock, JL Horovitz, J Hamilton, RG Santangelo, C Schal, ... Insect Biochemistry and Molecular Biology 39 (8), 568-577, 2009 | 53 | 2009 |
Blueprint for a pop-up SARS-CoV-2 testing lab Nature Biotechnology 38 (7), 791-797, 2020 | 52 | 2020 |
CRISPR–Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells E Lin-Shiao, WG Pfeifer, BR Shy, M Saffari Doost, E Chen, VS Vykunta, ... Nucleic acids research 50 (3), 1256-1268, 2022 | 50 | 2022 |
Human papillomavirus 16E6 and NFX1-123 potentiate Notch signaling and differentiation without activating cellular arrest PA Vliet-Gregg, JR Hamilton, RA Katzenellenbogen Virology 478, 50-60, 2015 | 41 | 2015 |
NFX1-123 and human papillomavirus 16E6 increase Notch expression in keratinocytes PA Vliet-Gregg, JR Hamilton, RA Katzenellenbogen Journal of virology 87 (24), 13741-13750, 2013 | 40 | 2013 |
Targeting antigen to the surface of EVs improves the in vivo immunogenicity of human and non-human adenoviral vaccines in mice CM Bliss, AJ Parsons, R Nachbagauer, JR Hamilton, F Cappuccini, ... Molecular Therapy-Methods & Clinical Development 16, 108-125, 2020 | 39 | 2020 |
DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection BS Chambers, BE Heaton, K Rausch, RE Dumm, JR Hamilton, S Cherry, ... Nature microbiology 4 (11), 1964-1977, 2019 | 33 | 2019 |
Peptidoglycan induces necrosis and regulates cytokine production in murine trophoblast stem cells JA Rose, JJ Rabenold, MM Parast, DS Milstone, VM Abrahams, JK Riley American Journal of Reproductive Immunology 66 (3), 209-222, 2011 | 27 | 2011 |
Launching a saliva-based SARS-CoV-2 surveillance testing program on a university campus AJ Ehrenberg, EA Moehle, CE Brook, AH Doudna Cate, LB Witkowsky, ... PLoS One 16 (5), e0251296, 2021 | 22 | 2021 |
Robotic RNA extraction for SARS-CoV-2 surveillance using saliva samples JR Hamilton, EC Stahl, CA Tsuchida, E Lin-Shiao, CK Tsui, K Pestal, ... PloS one 16 (8), e0255690, 2021 | 18 | 2021 |
Alveolar macrophages are critical for broadly-reactive antibody-mediated protection against influenza A virus in mice. Nat Commun 8: 846 W He, CJ Chen, CE Mullarkey, JR Hamilton, CK Wong, PE Leon, ... | 18 | 2017 |
Knocking out barriers to engineered cell activity JR Hamilton, JA Doudna Science 367 (6481), 976-977, 2020 | 14 | 2020 |
In vivo human T cell engineering with enveloped delivery vehicles JR Hamilton, E Chen, BS Perez, CR Sandoval Espinoza, MH Kang, ... Nature Biotechnology, 1-9, 2024 | 13 | 2024 |