Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence G Genovese, AK Kähler, RE Handsaker, J Lindberg, SA Rose, ... New England Journal of Medicine 371 (26), 2477-2487, 2014 | 3405 | 2014 |
Chromosomal instability drives metastasis through a cytosolic DNA response SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ... Nature 553 (7689), 467-472, 2018 | 1260 | 2018 |
Mechanisms of chromosomal instability SL Thompson, SF Bakhoum, DA Compton Current Biology 20 (6), R285-R295, 2010 | 722 | 2010 |
The cytosolic DNA-sensing cGAS–STING pathway in cancer J Kwon, SF Bakhoum Cancer discovery 10 (1), 26-39, 2020 | 700 | 2020 |
The multifaceted role of chromosomal instability in cancer and its microenvironment SF Bakhoum, LC Cantley Cell 174 (6), 1347-1360, 2018 | 575 | 2018 |
A molecular single-cell lung atlas of lethal COVID-19 JC Melms, J Biermann, H Huang, Y Wang, A Nair, S Tagore, I Katsyv, ... Nature 595 (7865), 114-119, 2021 | 517 | 2021 |
Genome stability is ensured by temporal control of kinetochore–microtubule dynamics SF Bakhoum, SL Thompson, AL Manning, DA Compton Nature cell biology 11 (1), 27-35, 2009 | 514 | 2009 |
Deviant kinetochore microtubule dynamics underlie chromosomal instability SF Bakhoum, G Genovese, DA Compton Current Biology 19 (22), 1937-1942, 2009 | 389 | 2009 |
Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations PR Loh, G Genovese, RE Handsaker, HK Finucane, YA Reshef, ... Nature 559 (7714), 350-355, 2018 | 333 | 2018 |
Regenerative lineages and immune-mediated pruning in lung cancer metastasis AM Laughney, J Hu, NR Campbell, SF Bakhoum, M Setty, VP Lavallée, ... Nature medicine 26 (2), 259-269, 2020 | 325 | 2020 |
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients B Nguyen, C Fong, A Luthra, SA Smith, RG DiNatale, S Nandakumar, ... Cell 185 (3), 563-575. e11, 2022 | 322 | 2022 |
Chromosomal instability and cancer: a complex relationship with therapeutic potential SF Bakhoum, DA Compton The Journal of clinical investigation 122 (4), 1138-1143, 2012 | 319 | 2012 |
Pervasive chromosomal instability and karyotype order in tumour evolution TBK Watkins, EL Lim, M Petkovic, S Elizalde, NJ Birkbak, GA Wilson, ... Nature 587 (7832), 126-132, 2020 | 294 | 2020 |
The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells AL Manning, NJ Ganem, SF Bakhoum, M Wagenbach, L Wordeman, ... Molecular biology of the cell 18 (8), 2970-2979, 2007 | 262 | 2007 |
A predictive model of complications after spine surgery: the National Surgical Quality Improvement Program (NSQIP) 2005–2010 K Bekelis, A Desai, SF Bakhoum, S Missios The Spine Journal 14 (7), 1247-1255, 2014 | 189 | 2014 |
Metastasis and immune evasion from extracellular cGAMP hydrolysis J Li, MA Duran, N Dhanota, WK Chatila, SE Bettigole, J Kwon, RK Sriram, ... Cancer discovery 11 (5), 1212-1227, 2021 | 183 | 2021 |
Limited environmental serine and glycine confer brain metastasis sensitivity to PHGDH inhibition B Ngo, E Kim, V Osorio-Vasquez, S Doll, S Bustraan, RJ Liang, A Luengo, ... Cancer discovery 10 (9), 1352-1373, 2020 | 180 | 2020 |
The mitotic origin of chromosomal instability SF Bakhoum, WT Silkworth, IK Nardi, JM Nicholson, DA Compton, ... Current Biology 24 (4), R148-R149, 2014 | 171 | 2014 |
Chromosomal instability as a driver of tumor heterogeneity and evolution SF Bakhoum, DA Landau Cold Spring Harbor perspectives in medicine 7 (6), a029611, 2017 | 168 | 2017 |
DNA-damage response during mitosis induces whole-chromosome missegregation SF Bakhoum, L Kabeche, JP Murnane, BI Zaki, DA Compton Cancer discovery 4 (11), 1281-1289, 2014 | 166 | 2014 |