| Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β CE Zielinski, F Mele, D Aschenbrenner, D Jarrossay, F Ronchi, ... Nature 484 (7395), 514-518, 2012 | 1105 | 2012 |
| A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis T Schwerd, SRF Twigg, D Aschenbrenner, S Manrique, KA Miller, ... Journal of Experimental Medicine 214 (9), 2547-2562, 2017 | 193 | 2017 |
| A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 186 | 2022 |
| The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly F Zhang, D Aschenbrenner, JY Yoo, T Zuo The Lancet Microbe 3 (12), e969-e983, 2022 | 156 | 2022 |
| Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis D Hu, S Notarbartolo, T Croonenborghs, B Patel, R Cialic, TH Yang, ... Nature communications 8 (1), 1600, 2017 | 124 | 2017 |
| Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome V Béziat, SJ Tavernier, YH Chen, CS Ma, M Materna, A Laurence, J Staal, ... Journal of Experimental Medicine 217 (6), 2020 | 112 | 2020 |
| An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells D Aschenbrenner, M Foglierini, D Jarrossay, D Hu, HL Weiner, ... Nature immunology 19 (10), 1126-1136, 2018 | 102 | 2018 |
| Selective loss of function variants in IL6ST cause Hyper-IgE syndrome with distinct impairments of T-cell phenotype and function T Shahin, D Aschenbrenner, D Cagdas, SK Bal, CD Conde, W Garncarz, ... haematologica 104 (3), 609, 2019 | 99 | 2019 |
| Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance D Aschenbrenner, M Quaranta, S Banerjee, N Ilott, J Jansen, B Steere, ... Gut 70 (6), 1023-1036, 2021 | 79 | 2021 |
| Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis D Trzupek, M Dunstan, AJ Cutler, M Lee, L Godfrey, L Jarvis, DB Rainbow, ... Genome medicine 12, 1-22, 2020 | 76 | 2020 |
| Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice L Wang, D Aschenbrenner, Z Zeng, X Cao, D Mayr, M Mehta, M Capitani, ... Nature genetics 53 (4), 500-510, 2021 | 75 | 2021 |
| An integrated taxonomy for monogenic inflammatory bowel disease C Bolton, CS Smillie, S Pandey, R Elmentaite, G Wei, C Argmann, ... Gastroenterology 162 (3), 859-876, 2022 | 56 | 2022 |
| Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome YH Chen, G Grigelioniene, PT Newton, J Gullander, M Elfving, ... Journal of Experimental Medicine 217 (3), e20191306, 2020 | 53 | 2020 |
| ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells F Mele, C Basso, C Leoni, D Aschenbrenner, S Becattini, D Latorre, ... Nature communications 6 (1), 6431, 2015 | 37 | 2015 |
| Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ DJ Swan, D Aschenbrenner, CA Lamb, K Chakraborty, J Clark, S Pandey, ... Haematologica 104 (10), e483, 2019 | 28 | 2019 |
| A variant in IL6ST with a selective IL-11 signaling defect in human and mouse T Schwerd, F Krause, SRF Twigg, D Aschenbrenner, YH Chen, ... Bone research 8 (1), 24, 2020 | 24 | 2020 |
| Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19 CP Kotanidis, C Xie, D Alexander, JCL Rodrigues, K Burnham, A Mentzer, ... The Lancet Digital Health 4 (10), e705-e716, 2022 | 19 | 2022 |
| A gene locus that controls expression of ACE2 in virus infection MA Ansari, E Marchi, N Ramamurthy, D Aschenbrenner, CP Hackstein, ... medRxiv, 2020.04. 26.20080408, 2020 | 7 | 2020 |
| A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease T Thomas, C Rich-Griffin, M Pohin, M Friedrich, D Aschenbrenner, ... bioRxiv, 2023.05. 05.539635, 2023 | 6 | 2023 |
| Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism A Cavounidis, S Pandey, M Capitani, M Friedrich, A Cross, L Gartner, ... Mucosal Immunology 15 (6), 1431-1446, 2022 | 5 | 2022 |
