Studies on the mechanism of hypoxic selectivity in copper bis (thiosemicarbazone) radiopharmaceuticals RI Maurer, PJ Blower, JR Dilworth, CA Reynolds, Y Zheng, GED Mullen Journal of medicinal chemistry 45 (7), 1420-1431, 2002 | 235 | 2002 |
Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor YL Liang, M Khoshouei, G Deganutti, A Glukhova, C Koole, TS Peat, ... Nature 561 (7724), 492-497, 2018 | 232 | 2018 |
Atomic charges for variable molecular conformations CA Reynolds, JW Essex, WG Richards Journal of the American Chemical Society 114 (23), 9075-9079, 1992 | 191 | 1992 |
Dimerization and domain swapping in G-protein-coupled receptors: a computational study PR Gouldson, C Higgs, RE Smith, MK Dean, GV Gkoutos, CA Reynolds Neuropsychopharmacology 23 (4), S60-S77, 2000 | 183 | 2000 |
Dimerization of G-protein-coupled receptors MK Dean, C Higgs, RE Smith, RP Bywater, CR Snell, PD Scott, ... Journal of medicinal chemistry 44 (26), 4595-4614, 2001 | 175 | 2001 |
Semiempirical AM1 electrostatic potentials and AM1 electrostatic potential derived charges: A comparison with ab initio values GG Ferenczy, CA Reynolds, WG Richards Journal of computational chemistry 11 (2), 159-169, 1990 | 175 | 1990 |
Domain swapping in G-protein coupled receptor dimers. PR Gouldson, CR Snell, RP Bywater, C Higgs, CA Reynolds Protein engineering 11 (12), 1181-1193, 1998 | 157 | 1998 |
The extracellular surface of the GLP-1 receptor is a molecular trigger for biased agonism D Wootten, CA Reynolds, KJ Smith, JC Mobarec, C Koole, EE Savage, ... Cell 165 (7), 1632-1643, 2016 | 144 | 2016 |
Activation of the GLP-1 receptor by a non-peptidic agonist P Zhao, YL Liang, MJ Belousoff, G Deganutti, MM Fletcher, FS Willard, ... Nature 577 (7790), 432-436, 2020 | 132 | 2020 |
Towards new transition metal-based hypoxic selective agents for therapy and imaging PJ Blower, JR Dilworth, RI Maurer, GD Mullen, CA Reynolds, Y Zheng Journal of inorganic biochemistry 85 (1), 15-22, 2001 | 119 | 2001 |
Computed redox potentials and the design of bioreductive agents CA Reynolds, PM King, WG Richards Nature 334 (6177), 80-82, 1988 | 116 | 1988 |
Free energy calculations in molecular biophysics CA Reynolds, PM King, WG Richards Molecular Physics 76 (2), 251-275, 1992 | 112 | 1992 |
Toward the active conformations of rhodopsin and the β2‐adrenergic receptor PR Gouldson, NJ Kidley, RP Bywater, G Psaroudakis, HD Brooks, C Diaz, ... Proteins: Structure, Function, and Bioinformatics 56 (1), 67-84, 2004 | 107 | 2004 |
A New Approach to Docking in the β2-Adrenergic Receptor That Exploits the Domain Structure of G-Protein-Coupled Receptors PR Gouldson, CR Snell, CA Reynolds Journal of medicinal chemistry 40 (24), 3871-3886, 1997 | 105 | 1997 |
Receptor activity-modifying protein-directed G protein signaling specificity for the calcitonin gene-related peptide family of receptors C Weston, I Winfield, M Harris, R Hodgson, A Shah, SJ Dowell, ... Journal of Biological Chemistry 291 (42), 21925-21944, 2016 | 94 | 2016 |
Theoretical determination of partition coefficients JW Essex, CA Reynolds, WG Richards Journal of the American Chemical Society 114 (10), 3634-3639, 1992 | 88 | 1992 |
Do plants contain G protein-coupled receptors? B Taddese, GJG Upton, GR Bailey, SRD Jordan, NY Abdulla, PJ Reeves, ... Plant physiology 164 (1), 287-307, 2014 | 85 | 2014 |
Theoretical electrode potentials and conformational energies of benzoquinones and naphthoquinones in aqueous solution CA Reynolds Journal of the American Chemical Society 112 (21), 7545-7551, 1990 | 83 | 1990 |
Structure and Dynamics of Adrenomedullin Receptors AM1 and AM2 Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity … YL Liang, MJ Belousoff, MM Fletcher, X Zhang, M Khoshouei, G Deganutti, ... ACS pharmacology & translational science 3 (2), 263-284, 2020 | 75 | 2020 |
Modulation of glucagon receptor pharmacology by receptor activity-modifying protein-2 (RAMP2) C Weston, J Lu, N Li, K Barkan, GO Richards, DJ Roberts, TM Skerry, ... Journal of Biological Chemistry 290 (38), 23009-23022, 2015 | 75 | 2015 |