Systematic integration of molecular profiles identifies miR-22 as a regulator of lipid and folate metabolism in breast cancer cells C Koufaris, GN Valbuena, Y Pomyen, GD Tredwell, E Nevedomskaya, ... Oncogene 35 (21), 2766-2776, 2016 | 67 | 2016 |
Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens C Koufaris, J Wright, RA Currie, NJ Gooderham Toxicological Sciences 128 (2), 532-543, 2012 | 62 | 2012 |
Histone N-alpha terminal modifications: Genome regulation at the tip of the tail C Demetriadou, C Koufaris, A Kirmizis Epigenetics & chromatin 13 (1), 29, 2020 | 57 | 2020 |
Accurate breakpoint mapping in apparently balanced translocation families with discordant phenotypes using whole genome mate-pair sequencing C Aristidou, C Koufaris, A Theodosiou, M Bak, MM Mehrjouy, F Behjati, ... PLoS One 12 (1), e0169935, 2017 | 46 | 2017 |
Suppression of MTHFD2 in MCF-7 breast cancer cells increases glycolysis, dependency on exogenous glycine, and sensitivity to folate depletion C Koufaris, S Gallage, T Yang, CH Lau, GN Valbuena, HC Keun Journal of proteome research 15 (8), 2618-2625, 2016 | 46 | 2016 |
Modulation of the genome and epigenome of individuals susceptible to autism by environmental risk factors C Koufaris, C Sismani International journal of molecular sciences 16 (4), 8699-8718, 2015 | 43 | 2015 |
Repression of hedgehog signal transduction in T-lineage cells increases TCR-induced activation and proliferation NJ Rowbotham, AL Furmanski, AL Hager-Theodorides, SE Ross, ... Cell Cycle 7 (7), 904-908, 2008 | 40 | 2008 |
Protein interaction and functional data indicate MTHFD2 involvement in RNA processing and translation C Koufaris, R Nilsson Cancer & metabolism 6, 1-14, 2018 | 35 | 2018 |
The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) elicits estrogenic-like microRNA responses in breast cancer cells MD Papaioannou, C Koufaris, NJ Gooderham Toxicology letters 229 (1), 9-16, 2014 | 35 | 2014 |
Time and dose-dependent effects of phenobarbital on the rat liver miRNAome C Koufaris, J Wright, M Osborne, RA Currie, NJ Gooderham Toxicology 314 (2-3), 247-253, 2013 | 34 | 2013 |
A novel HCFC1 variant in male siblings with intellectual disability and microcephaly in the absence of cobalamin disorder C Koufaris, A Alexandrou, GA Tanteles, V Anastasiadou, C Sismani Biomedical Reports 4 (2), 215-218, 2016 | 31 | 2016 |
N-terminal acetyltransferases are cancer-essential genes prevalently upregulated in tumours C Koufaris, A Kirmizis Cancers 12 (9), 2631, 2020 | 26 | 2020 |
Mitochondrial MTHFD isozymes display distinct expression, regulation, and association with cancer R Nilsson, V Nicolaidou, C Koufaris Gene 716, 144032, 2019 | 26 | 2019 |
Human and primate‐specific microRNAs in cancer: Evolution, and significance in comparison with more distantly‐related research models: The great potential of evolutionary young … C Koufaris BioEssays 38 (3), 286-294, 2016 | 23 | 2016 |
Are differences in microRNA regulation implicated in species-dependent response to toxicological exposures? C Koufaris, NJ Gooderham toxicological sciences 131 (2), 337-342, 2013 | 22 | 2013 |
Using microRNA profiles to predict and evaluate hepatic carcinogenic potential NJ Gooderham, C Koufaris Toxicology Letters 228 (2), 127-132, 2014 | 20 | 2014 |
MicroRNA responses to environmental liver carcinogens: Biological and clinical significance V Nicolaidou, C Koufaris Clinica Chimica Acta 445, 25-33, 2015 | 19 | 2015 |
Haploinsufficiency of the miR-873/miR-876 microRNA cluster is associated with craniofacial abnormalities C Koufaris, G Papagregoriou, L Kousoulidou, M Moutafi, M Tauber, ... Gene 561 (1), 95-100, 2015 | 17 | 2015 |
Effects of treatment with androgen receptor ligands on microRNA expression of prostate cancer cells CV Segal, C Koufaris, C Powell, NJ Gooderham Toxicology 333, 45-52, 2015 | 15 | 2015 |
Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance C Demetriadou, A Raoukka, E Charidemou, C Mylonas, C Michael, ... Oncogene 41 (4), 571-585, 2022 | 11 | 2022 |