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Christopher L. Dearth, PhD
Christopher L. Dearth, PhD
Chief, Research & Surveillance Division, DoD-VA Extremity Trauma & Amputation Center of Excellence
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An acellular biologic scaffold promotes skeletal muscle formation in mice and humans with volumetric muscle loss
BM Sicari, JP Rubin, CL Dearth, MT Wolf, F Ambrosio, M Boninger, ...
Science translational medicine 6 (234), 234ra58-234ra58, 2014
5062014
The promotion of a constructive macrophage phenotype by solubilized extracellular matrix
BM Sicari, JL Dziki, BF Siu, CJ Medberry, CL Dearth, SF Badylak
Biomaterials 35 (30), 8605-8612, 2014
2682014
Macrophage polarization in response to ECM coated polypropylene mesh
MT Wolf, CL Dearth, CA Ranallo, ST LoPresti, LE Carey, KA Daly, ...
Biomaterials 35 (25), 6838-6849, 2014
2542014
Naturally derived and synthetic scaffolds for skeletal muscle reconstruction
MT Wolf, CL Dearth, SB Sonnenberg, EG Loboa, SF Badylak
Advanced drug delivery reviews 84, 208-221, 2015
2532015
ECM hydrogel coating mitigates the chronic inflammatory response to polypropylene mesh
DM Faulk, R Londono, MT Wolf, CA Ranallo, CA Carruthers, ...
Biomaterials 35 (30), 8585-8595, 2014
1862014
A murine model of volumetric muscle loss and a regenerative medicine approach for tissue replacement
BM Sicari, V Agrawal, BF Siu, CJ Medberry, CL Dearth, NJ Turner, ...
Tissue Engineering Part A 18 (19-20), 1941-1948, 2012
1782012
Polypropylene surgical mesh coated with extracellular matrix mitigates the host foreign body response
MT Wolf, CA Carruthers, CL Dearth, PM Crapo, A Huber, OA Burnsed, ...
Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2014
1532014
Solubilized extracellular matrix from brain and urinary bladder elicits distinct functional and phenotypic responses in macrophages
FW Meng, PF Slivka, CL Dearth, SF Badylak
Biomaterials 46, 131-140, 2015
952015
Preparation and characterization of a biologic scaffold from esophageal mucosa
TJ Keane, R Londono, RM Carey, CA Carruthers, JE Reing, CL Dearth, ...
Biomaterials 34 (28), 6729-6737, 2013
952013
Tissue engineering and regenerative medicine approaches to enhance the functional response to skeletal muscle injury
BM Sicari, CL Dearth, SF Badylak
The Anatomical Record 297 (1), 51-64, 2014
942014
Targeted rehabilitation after extracellular matrix scaffold transplantation for the treatment of volumetric muscle loss
NE Gentile, KM Stearns, EHP Brown, JP Rubin, ML Boninger, CL Dearth, ...
American Journal of Physical Medicine & Rehabilitation 93 (11), S79-S87, 2014
822014
Fractionation of an ECM hydrogel into structural and soluble components reveals distinctive roles in regulating macrophage behavior
PF Slivka, CL Dearth, TJ Keane, FW Meng, CJ Medberry, RT Riggio, ...
Biomaterials science 2 (10), 1521-1534, 2014
822014
The effect of terminal sterilization on the material properties and in vivo remodeling of a porcine dermal biologic scaffold
CL Dearth, TJ Keane, CA Carruthers, JE Reing, L Huleihel, CA Ranallo, ...
Acta biomaterialia 33, 78-87, 2016
812016
Histologic characterization of acellular dermal matrices in a porcine model of tissue expander breast reconstruction
CA Carruthers, CL Dearth, JE Reing, CR Kramer, DH Gagne, PM Crapo, ...
Tissue Engineering Part A 21 (1-2), 35-44, 2015
682015
The effect of mechanical loading upon extracellular matrix bioscaffold-mediated skeletal muscle remodeling
JL Dziki, RM Giglio, BM Sicari, DS Wang, RM Gandhi, R Londono, ...
Tissue Engineering Part A 24 (1-2), 34-46, 2018
652018
In vivo degradation of 14C-labeled porcine dermis biologic scaffold
LE Carey, CL Dearth, SA Johnson, R Londono, CJ Medberry, KA Daly, ...
Biomaterials 35 (29), 8297-8304, 2014
612014
Inhibition of COX1/2 alters the host response and reduces ECM scaffold mediated constructive tissue remodeling in a rodent model of skeletal muscle injury
CL Dearth, PF Slivka, SA Stewart, TJ Keane, JK Tay, R Londono, Q Goh, ...
Acta biomaterialia 31, 50-60, 2016
602016
Regenerative and rehabilitative medicine: a necessary synergy for functional recovery from volumetric muscle loss injury
SM Greising, CL Dearth, BT Corona
Cells Tissues Organs 202 (3-4), 237-249, 2016
582016
β2-Integrins contribute to skeletal muscle hypertrophy in mice
JS Marino, BJ Tausch, CL Dearth, MV Manacci, TJ McLoughlin, SJ Rakyta, ...
American Journal of Physiology-Cell Physiology 295 (4), C1026-C1036, 2008
512008
NIH-DoD-VA pain management collaboratory
RD Kerns, CA Brandt, P Peduzzi
Pain Medicine 20 (12), 2336-2345, 2019
492019
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