| Endothelin-A Novel Potent Vasoconstrictor Peptide Produced By Vascular Endothelial-Cells M Yanagisawa, H Kurihara, S Kimura, K Goto, T Masaki Faseb Journal 2 (4), A393-A393, 1988 | 14858* | 1988 |
| A novel potent vasoconstrictor peptide produced by vascular endothelial cells M Yanagisawa, H Kurihara, S Kimura, Y Tomobe, M Kobayashi, Y Mitsui, ... nature 332 (6163), 411, 1988 | 14832 | 1988 |
| Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior (vol 92, pg 573, 1998) T Sakurai, A Amemiya, M Ishii, I Matsuzaki, RM Chemelli, H Tanaka, ... Cell 92 (5), U29-U29, 1998 | 6596* | 1998 |
| Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior T Sakurai, A Amemiya, M Ishii, I Matsuzaki, RM Chemelli, H Tanaka, ... Cell 92 (4), 573-585, 1998 | 6596 | 1998 |
| Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation RM Chemelli, JT Willie, CM Sinton, JK Elmquist, T Scammell, C Lee, ... Cell 98 (4), 437-451, 1999 | 3674 | 1999 |
| The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes A Inoue, M Yanagisawa, S Kimura, Y Kasuya, T Miyauchi, K Goto, ... Proceedings of the National Academy of Sciences 86 (8), 2863-2867, 1989 | 3564 | 1989 |
| Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor T Sakurai, M Yanagisawa, Y Takuwat, H Miyazakit, S Kimura, K Goto, ... Nature 348 (6303), 732, 1990 | 3058 | 1990 |
| Expression of endothelin-1 in the lungs of patients with pulmonary hypertension A Giaid, M Yanagisawa, D Langleben, RP Michel, R Levy, H Shennib, ... New England Journal of Medicine 328 (24), 1732-1739, 1993 | 2464 | 1993 |
| Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 BS Samuel, A Shaito, T Motoike, FE Rey, F Backhed, JK Manchester, ... Proceedings of the National Academy of Sciences 105 (43), 16767-16772, 2008 | 1827 | 2008 |
| Differential expression of orexin receptors 1 and 2 in the rat brain JN Marcus, CJ Aschkenasi, CE Lee, RM Chemelli, CB Saper, ... Journal of Comparative Neurology 435 (1), 6-25, 2001 | 1814 | 2001 |
| Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity J Hara, CT Beuckmann, T Nambu, JT Willie, RM Chemelli, CM Sinton, ... Neuron 30 (2), 345-354, 2001 | 1646 | 2001 |
| Tie2-Cre Transgenic Mice: A New Model for Endothelial Cell-Lineage Analysis in Vivo YY Kisanuki, RE Hammer, J Miyazaki, SC Williams, JA Richardson, ... Developmental biology 230 (2), 230-242, 2001 | 1397 | 2001 |
| Distribution of orexin neurons in the adult rat brain1 T Nambu, T Sakurai, K Mizukami, Y Hosoya, M Yanagisawa, K Goto Brain research 827 (1-2), 243-260, 1999 | 1301 | 1999 |
| Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems Y Date, Y Ueta, H Yamashita, H Yamaguchi, S Matsukura, K Kangawa, ... Proceedings of the National Academy of Sciences 96 (2), 748-753, 1999 | 1251 | 1999 |
| Targeted and natural (piebald-lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice K Hosoda, RE Hammer, JA Richardson, AG Baynash, JC Cheung, ... Cell 79 (7), 1267-1276, 1994 | 1195 | 1994 |
| ECE-1: a membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1 D Xu, N Emoto, A Giaid, C Slaughter, S Kaw, M Yanagisawa Cell 78 (3), 473-485, 1994 | 1182 | 1994 |
| Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons AG Baynash, K Hosoda, A Giaid, JA Richardson, N Emoto, RE Hammer, ... Cell 79 (7), 1277-1285, 1994 | 1153 | 1994 |
| A missense mutation of the endothelin-B receptor gene in multigenic Hirschsprung's disease EG Puffenberger, K Hosoda, SS Washington, K Nakao, M Yanagisawa, ... Cell 79 (7), 1257-1266, 1994 | 1134 | 1994 |
| Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation JL Pluznick, RJ Protzko, H Gevorgyan, Z Peterlin, A Sipos, J Han, I Brunet, ... Proceedings of the National Academy of Sciences 110 (11), 4410-4415, 2013 | 1124 | 2013 |
| Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome T Tanaka, J Yamamoto, S Iwasaki, H Asaba, H Hamura, Y Ikeda, ... Proceedings of the National Academy of Sciences 100 (26), 15924-15929, 2003 | 1090 | 2003 |
