Molecular pharmacology of VEGF-A isoforms: binding and signalling at VEGFR2 CJ Peach, VW Mignone, MA Arruda, DC Alcobia, SJ Hill, LE Kilpatrick, ... International journal of molecular sciences 19 (4), 1264, 2018 | 414 | 2018 |
IL-17 expression by breast-cancer-associated macrophages: IL-17 promotes invasiveness of breast cancer cell lines XW Zhu, LA Mulcahy, RAA Mohammed, AHS Lee, HA Franks, L Kilpatrick, ... Breast Cancer Research 10, 1-11, 2008 | 311 | 2008 |
Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism R Corriden, LE Kilpatrick, B Kellam, SJ Briddon, SJ Hill The FASEB Journal 28 (10), 4211, 2014 | 184 | 2014 |
Binding kinetics of ligands acting at GPCRs DA Sykes, LA Stoddart, LE Kilpatrick, SJ Hill Molecular and cellular endocrinology 485, 9-19, 2019 | 99 | 2019 |
NanoBRET approaches to study ligand binding to GPCRs and RTKs LA Stoddart, LE Kilpatrick, SJ Hill Trends in pharmacological sciences 39 (2), 136-147, 2018 | 98 | 2018 |
Probing the pharmacology of G protein-coupled receptors with fluorescent ligands LA Stoddart, LE Kilpatrick, SJ Briddon, SJ Hill Neuropharmacology 98, 48-57, 2015 | 97 | 2015 |
Studying GPCR pharmacology in membrane microdomains: fluorescence correlation spectroscopy comes of age SJ Briddon, LE Kilpatrick, SJ Hill Trends in pharmacological sciences 39 (2), 158-174, 2018 | 71 | 2018 |
Transactivation of G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs): Recent insights using luminescence and fluorescence technologies LE Kilpatrick, SJ Hill Current Opinion in Endocrine and Metabolic Research 16, 102-112, 2021 | 59 | 2021 |
Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor … LE Kilpatrick, R Friedman-Ohana, DC Alcobia, K Riching, CJ Peach, ... Biochemical Pharmacology 136, 62-75, 2017 | 56 | 2017 |
Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the … LE Kilpatrick, SJ Briddon, ND Holliday Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (6), 1068-1081, 2012 | 51 | 2012 |
Quantitative analysis of neuropeptide Y receptor association with β‐arrestin2 measured by bimolecular fluorescence complementation LE Kilpatrick, SJ Briddon, SJ Hill, ND Holliday British journal of pharmacology 160 (4), 892-906, 2010 | 51 | 2010 |
Quantifying target occupancy of small molecules within living cells MB Robers, R Friedman-Ohana, KVM Huber, L Kilpatrick, JD Vasta, ... Annual review of biochemistry 89 (1), 557-581, 2020 | 43 | 2020 |
Real-time ligand binding of fluorescent VEGF-A isoforms that discriminate between VEGFR2 and NRP1 in living cells CJ Peach, LE Kilpatrick, R Friedman-Ohana, K Zimmerman, MB Robers, ... Cell chemical biology 25 (10), 1208-1218. e5, 2018 | 40 | 2018 |
Complex Formation between VEGFR2 and the β2-Adrenoceptor LE Kilpatrick, DC Alcobia, CW White, CJ Peach, JR Glenn, K Zimmerman, ... Cell Chemical Biology 26 (6), 830-841. e9, 2019 | 37 | 2019 |
Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor E Comeo, ND Kindon, M Soave, LA Stoddart, LE Kilpatrick, PJ Scammells, ... Journal of Medicinal Chemistry 63 (5), 2656-2672, 2019 | 35 | 2019 |
AG Protein–Coupled Receptor Dimer Imaging Assay Reveals Selectively Modified Pharmacology of Neuropeptide Y Y1/Y5 Receptor Heterodimers LE Kilpatrick, LJ Humphrys, ND Holliday Molecular pharmacology 87 (4), 718-732, 2015 | 25 | 2015 |
The use of fluorescence correlation spectroscopy to characterize the molecular mobility of fluorescently labelled G protein-coupled receptors LE Kilpatrick, SJ Hill Biochemical Society Transactions 44 (2), 624-629, 2016 | 22 | 2016 |
Kinetic analysis of the early signaling steps of the human chemokine receptor CXCR4 C Perpiñá-Viciano, A Işbilir, A Zarca, B Caspar, LE Kilpatrick, SJ Hill, ... Molecular Pharmacology 98 (2), 72-87, 2020 | 17 | 2020 |
Use of NanoBiT and NanoBRET to monitor fluorescent VEGF‐A binding kinetics to VEGFR2/NRP1 heteromeric complexes in living cells CJ Peach, LE Kilpatrick, J Woolard, SJ Hill British Journal of Pharmacology 178 (12), 2393-2411, 2021 | 16 | 2021 |
Detection of genome‐edited and endogenously expressed G protein‐coupled receptors M Soave, LA Stoddart, CW White, LE Kilpatrick, J Goulding, SJ Briddon, ... The FEBS Journal 288 (8), 2585-2601, 2021 | 16 | 2021 |