Systematic identification of trans eQTLs as putative drivers of known disease associations HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ... Nature genetics 45 (10), 1238-1243, 2013 | 1901 | 2013 |
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL T Vaisar, S Pennathur, PS Green, SA Gharib, AN Hoofnagle, MC Cheung, ... The Journal of clinical investigation 117 (3), 746-756, 2007 | 1120 | 2007 |
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 845 | 2021 |
Epigenetic signatures of cigarette smoking R Joehanes, AC Just, RE Marioni, LC Pilling, LM Reynolds, ... Circulation: cardiovascular genetics 9 (5), 436-447, 2016 | 812 | 2016 |
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function DB Hancock, M Eijgelsheim, JB Wilk, SA Gharib, LR Loehr, KD Marciante, ... Nature genetics 42 (1), 45-52, 2010 | 720 | 2010 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 615 | 2019 |
The transcriptional landscape of age in human peripheral blood MJ Peters, R Joehanes, LC Pilling, C Schurmann, KN Conneely, J Powell, ... Nature communications 6 (1), 1-14, 2015 | 613 | 2015 |
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 499 | 2018 |
Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks F Demenais, P Margaritte-Jeannin, KC Barnes, WOC Cookson, ... Nature genetics 50 (1), 42-53, 2018 | 493 | 2018 |
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function MS Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, ... Nature genetics 43 (11), 1082-1090, 2011 | 478 | 2011 |
Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis C Hung, G Linn, YH Chow, A Kobayashi, K Mittelsteadt, WA Altemeier, ... American journal of respiratory and critical care medicine 188 (7), 820-830, 2013 | 402 | 2013 |
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction N Sotoodehnia, A Isaacs, PIW De Bakker, M Dörr, C Newton-Cheh, ... Nature genetics 42 (12), 1068-1076, 2010 | 385 | 2010 |
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis BD Hobbs, K De Jong, M Lamontagne, Y Bossé, N Shrine, MS Artigas, ... Nature genetics 49 (3), 426-432, 2017 | 375 | 2017 |
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations P Sakornsakolpat, D Prokopenko, M Lamontagne, NF Reeve, AL Guyatt, ... Nature genetics 51 (3), 494-505, 2019 | 302 | 2019 |
Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis G Campanholle, G Ligresti, SA Gharib, JS Duffield American Journal of Physiology-Cell Physiology 304 (7), C591-C603, 2013 | 236 | 2013 |
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits E Porcu, S Rüeger, K Lepik, FA Santoni, A Reymond, Z Kutalik Nature communications 10 (1), 3300, 2019 | 232 | 2019 |
Genome-Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction JB Wilk, NRG Shrine, LR Loehr, JH Zhao, A Manichaikul, LM Lopez, ... American journal of respiratory and critical care medicine 186 (7), 622-632, 2012 | 232 | 2012 |
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury C Schrimpf, C Xin, G Campanholle, SE Gill, W Stallcup, SL Lin, GE Davis, ... Journal of the American Society of Nephrology 23 (5), 868-883, 2012 | 227 | 2012 |
Prediction of mechanical properties of human atherosclerotic tissue by high-frequency intravascular ultrasound imaging. An in vitro study. RT Lee, SG Richardson, HM Loree, AJ Grodzinsky, SA Gharib, FJ Schoen, ... Arteriosclerosis and thrombosis: a journal of vascular biology 12 (1), 1-5, 1992 | 203 | 1992 |
Modulation of lipopolysaccharide-induced gene transcription and promotion of lung injury by mechanical ventilation WA Altemeier, G Matute-Bello, SA Gharib, RW Glenny, TR Martin, ... The Journal of Immunology 175 (5), 3369-3376, 2005 | 194 | 2005 |