| Remarkable potential of the α-aminophosphonate/phosphinate structural motif in medicinal chemistry A Mucha, P Kafarski, Ł Berlicki Journal of Medicinal Chemistry 54 (17), 5955-5980, 2011 | 696 | 2011 |
| The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity J Grembecka, A Mucha, T Cierpicki, P Kafarski Journal of Medicinal Chemistry 46 (13), 2641-2655, 2003 | 276 | 2003 |
| Structural basis for the inhibition of the essential Plasmodium falciparum M1 neutral aminopeptidase S McGowan, CJ Porter, J Lowther, CM Stack, SJ Golding, ... Proceedings of the National Academy of Sciences 106 (8), 2537-2542, 2009 | 182 | 2009 |
| Characterization of the Plasmodium falciparum M17 leucyl aminopeptidase: a protease involved in amino acid regulation with potential for antimalarial drug development CM Stack, J Lowther, E Cunningham, S Donnelly, DL Gardiner, ... Journal of Biological Chemistry 282 (3), 2069-2080, 2007 | 161 | 2007 |
| Metallo-aminopeptidase inhibitors A Mucha, M Drag, JP Dalton, P Kafarski Biochimie 92 (11), 1509-1529, 2010 | 157 | 2010 |
| Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials TS Skinner-Adams, CM Stack, KR Trenholme, CL Brown, J Grembecka, ... Trends in Biochemical Sciences 35 (1), 53-61, 2010 | 153 | 2010 |
| Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: a structure− activity study S Vassiliou, A Mucha, P Cuniasse, D Georgiadis, K Lucet-Levannier, ... Journal of medicinal chemistry 42 (14), 2610-2620, 1999 | 143 | 1999 |
| Crystal structures of active LytM M Firczuk, A Mucha, M Bochtler Journal of molecular biology 354 (3), 578-590, 2005 | 122 | 2005 |
| Identification of Phosphinate Dipeptide Analog Inhibitors Directed against the Plasmodium falciparum M17 Leucine Aminopeptidase as Lead Antimalarial … TS Skinner-Adams, J Lowther, F Teuscher, CM Stack, J Grembecka, ... Journal of Medicinal Chemistry 50 (24), 6024-6031, 2007 | 114 | 2007 |
| Structure of the Plasmodium falciparum M17 aminopeptidase and significance for the design of drugs targeting the neutral exopeptidases S McGowan, CA Oellig, WA Birru, TT Caradoc-Davies, CM Stack, ... Proceedings of the National Academy of Sciences 107 (6), 2449-2454, 2010 | 102 | 2010 |
| Membrane type-1 matrix metalloprotease and stromelysin-3 cleave more efficiently synthetic substrates containing unusual amino acids in their P1′ positions A Mucha, P Cuniasse, R Kannan, F Beau, A Yiotakis, P Basset, V Dive Journal of Biological Chemistry 273 (5), 2763-2768, 1998 | 78 | 1998 |
| Synthesis and modifications of phosphinic dipeptide analogues A Mucha Molecules 17 (11), 13530-13568, 2012 | 73 | 2012 |
| The M18 aspartyl aminopeptidase of the human malaria parasite Plasmodium falciparum F Teuscher, J Lowther, TS Skinner-Adams, T Spielmann, MWA Dixon, ... Journal of Biological Chemistry 282 (42), 30817-30826, 2007 | 70 | 2007 |
| Structural insights into substrate selectivity and activity of bacterial polyphosphate kinases BP Nocek, AN Khusnutdinova, M Ruszkowski, R Flick, M Burda, ... ACS Catalysis 8 (11), 10746-10760, 2018 | 69 | 2018 |
| Structure-guided, single-point modifications in the phosphinic dipeptide structure yield highly potent and selective inhibitors of neutral aminopeptidases S Vassiliou, E Weglarz-Tomczak, Ł Berlicki, M Pawełczak, B Nocek, ... Journal of medicinal chemistry 57 (19), 8140-8151, 2014 | 62 | 2014 |
| Insight into the mechanism of three component condensation leading to aminomethylenebisphosphonates E Dąbrowska, A Burzyńska, A Mucha, E Matczak-Jon, ... Journal of Organometallic Chemistry 694 (23), 3806-3813, 2009 | 51 | 2009 |
| High-performance liquid chromatographic enantiomer separation and determination of absolute configurations of phosphinic acid analogues of dipeptides and their α … M Lämmerhofer, D Hebenstreit, E Gavioli, W Lindner, A Mucha, P Kafarski, ... Tetrahedron: Asymmetry 14 (17), 2557-2565, 2003 | 46 | 2003 |
| The preparation of phosphono peptides containing a phosphonamidate bond A Mucha, P Kafarski, F Plenat, HJ Cristau Tetrahedron 50 (44), 12743-12754, 1994 | 46 | 1994 |
| Stereoselective separations of chiral phosphinic acid pseudodipeptides by CEC using silica monoliths modified with an anion‐exchange‐type chiral selector B Preinerstorfer, D Lubda, A Mucha, P Kafarski, W Lindner, ... Electrophoresis 27 (21), 4312-4320, 2006 | 45 | 2006 |
| A synthetic method for diversification of the P1′ substituent in phosphinic dipeptides as a tool for exploration of the specificity of the S1′ binding pockets of leucine … S Vassiliou, M Xeilari, A Yiotakis, J Grembecka, M Pawełczak, P Kafarski, ... Bioorganic & medicinal chemistry 15 (9), 3187-3200, 2007 | 42 | 2007 |
