Rare and low-frequency coding variants alter human adult height E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ... Nature 542 (7640), 186-190, 2017 | 654 | 2017 |
Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758-1766, 2017 | 545 | 2017 |
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes A Mahajan, J Wessel, SM Willems, W Zhao, NR Robertson, AY Chu, ... Nature genetics 50 (4), 559-571, 2018 | 423 | 2018 |
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, ... Nature genetics 50 (1), 26-41, 2018 | 339 | 2018 |
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls J Flannick, JM Mercader, C Fuchsberger, MS Udler, A Mahajan, J Wessel, ... Nature 570 (7759), 71-76, 2019 | 291 | 2019 |
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility J Wessel, AY Chu, SM Willems, S Wang, H Yaghootkar, JA Brody, ... Nature communications 6 (1), 5897, 2015 | 231 | 2015 |
Methodological standards for meta-analyses and qualitative systematic reviews of cardiac prevention and treatment studies: a scientific statement from the American Heart … G Rao, F Lopez-Jimenez, J Boyd, F D’Amico, NH Durant, MA Hlatky, ... Circulation 136 (10), e172-e194, 2017 | 218 | 2017 |
Generalized genomic distance–based regression methodology for multilocus association analysis J Wessel, NJ Schork The American Journal of Human Genetics 79 (5), 792-806, 2006 | 213 | 2006 |
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease RA Scott, DF Freitag, L Li, AY Chu, P Surendran, R Young, N Grarup, ... Science translational medicine 8 (341), 341ra76-341ra76, 2016 | 124 | 2016 |
A comprehensive literature review of haplotyping software and methods for use with unrelated individuals RM Salem, J Wessel, NJ Schork Human Genomics 2, 1-28, 2005 | 122 | 2005 |
C-reactive protein, an ‘intermediate phenotype’for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the … J Wessel, G Moratorio, F Rao, M Mahata, L Zhang, W Greene, BK Rana, ... Journal of hypertension 25 (2), 329-343, 2007 | 119 | 2007 |
Genome-wide meta-analyses of smoking behaviors in African Americans SP David, A Hamidovic, GK Chen, AW Bergen, J Wessel, JL Kasberger, ... Translational psychiatry 2 (5), e119-e119, 2012 | 114 | 2012 |
Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood … F Rao, L Zhang, J Wessel, K Zhang, G Wen, BP Kennedy, BK Rana, ... Circulation 116 (9), 993-1006, 2007 | 108 | 2007 |
Discovery of common human genetic variants of GTP cyclohydrolase 1 (GCH1) governing nitric oxide, autonomic activity, and cardiovascular risk L Zhang, F Rao, K Zhang, S Khandrika, M Das, SM Vaingankar, X Bao, ... The Journal of clinical investigation 117 (9), 2658-2671, 2007 | 103 | 2007 |
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution AE Justice, T Karaderi, HM Highland, KL Young, M Graff, Y Lu, V Turcot, ... Nature genetics 51 (3), 452-469, 2019 | 100 | 2019 |
Methods and Systems for Incorporating Multiple Environmental and Genetic Risk Factors E Halperin, J Wessel, M Cargill, DA Stephan US Patent App. 12/558,345, 2010 | 100 | 2010 |
Rho kinase polymorphism influences blood pressure and systemic vascular resistance in human twins: role of heredity TM Seasholtz, J Wessel, F Rao, BK Rana, S Khandrika, BP Kennedy, ... Hypertension 47 (5), 937-947, 2006 | 100 | 2006 |
Heritability and clinical features of multigenerational families with obsessive‐compulsive disorder and hoarding CA Mathews, CM Nievergelt, A Azzam, H Garrido, DA Chavira, J Wessel, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144 …, 2007 | 96 | 2007 |
Functional allelic heterogeneity and pleiotropy of a repeat polymorphism in tyrosine hydroxylase: prediction of catecholamines and response to stress in twins L Zhang, F Rao, J Wessel, BP Kennedy, BK Rana, L Taupenot, EO Lillie, ... Physiological Genomics 19 (3), 277-291, 2004 | 96 | 2004 |
Methods and Systems for Genomic Analysis Using Ancestral Data DA Stephan, J Wessel, M Cargill, E Halperin US Patent App. 12/239,718, 2009 | 91 | 2009 |