The cancer chemotherapeutic paclitaxel increases human and rodent sensory neuron responses to TRPV1 by activation of TLR4 Y Li, P Adamek, H Zhang, CE Tatsui, LD Rhines, P Mrozkova, Q Li, ... Journal of Neuroscience 35 (39), 13487-13500, 2015 | 235 | 2015 |
Mechanisms involved in the development of chemotherapy-induced neuropathy JA Boyette-Davis, ET Walters, PM Dougherty Pain management 5 (4), 285-296, 2015 | 183 | 2015 |
Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy H Zhang, PM Dougherty Anesthesiology 120 (6), 1463-1475, 2014 | 167 | 2014 |
Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat CR Robinson, H Zhang, PM Dougherty Neuroscience 274, 308-317, 2014 | 148 | 2014 |
A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-α H Zhang, H Nei, PM Dougherty Journal of Neuroscience 30 (38), 12844-12855, 2010 | 136 | 2010 |
MAPK signaling downstream to TLR4 contributes to paclitaxel-induced peripheral neuropathy Y Li, H Zhang, AK Kosturakis, RM Cassidy, H Zhang, ... Brain, behavior, and immunity 49, 255-266, 2015 | 127 | 2015 |
Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy JH Kim, PM Dougherty, S Abdi Gynecologic oncology 136 (3), 453-459, 2015 | 102 | 2015 |
Subclinical peripheral neuropathy is a common finding in colorectal cancer patients prior to chemotherapy JA Boyette-Davis, C Eng, XS Wang, CS Cleeland, ... Clinical Cancer Research 18 (11), 3180-3187, 2012 | 74 | 2012 |
A quantitative sensory analysis of peripheral neuropathy in colorectal cancer and its exacerbation by oxaliplatin chemotherapy M de Carvalho Barbosa, AK Kosturakis, C Eng, G Wendelschafer-Crabb, ... Cancer research 74 (21), 5955-5962, 2014 | 73 | 2014 |
Spinal astrocyte gap junction and glutamate transporter expression contributes to a rat model of bortezomib-induced peripheral neuropathy CR Robinson, PM Dougherty Neuroscience 285, 1-10, 2015 | 45 | 2015 |
Subclinical peripheral neuropathy in patients with multiple myeloma before chemotherapy is correlated with decreased fingertip innervation density AK Kosturakis, Z He, Y Li, JA Boyette-Davis, N Shah, SK Thomas, ... Journal of Clinical Oncology 32 (28), 3156-3162, 2014 | 45 | 2014 |
Dynamic effects of TNF-α on synaptic transmission in mice over time following sciatic nerve chronic constriction injury H Zhang, H Zhang, PM Dougherty Journal of neurophysiology 110 (7), 1663-1671, 2013 | 45 | 2013 |
Acute inhibition of signalling phenotype of spinal GABAergic neurons by tumour necrosis factor‐α H Zhang, PM Dougherty The Journal of physiology 589 (18), 4511-4526, 2011 | 35 | 2011 |
Measuring therapy-induced peripheral neuropathy: preliminary development and validation of the treatment-induced neuropathy assessment scale TR Mendoza, XS Wang, LA Williams, Q Shi, EG Vichaya, PM Dougherty, ... The Journal of Pain 16 (10), 1032-1043, 2015 | 33 | 2015 |
Anatomy and physiology of somatosensory and pain processing SN Raja, PM Dougherty Essentials of pain medicine, 1-6, 2004 | 28 | 2004 |
Peripheral neuropathic pain: signs, symptoms, mechanisms, and causes: are they linked? LA Colvin, PM Dougherty British Journal of Anaesthesia 114 (3), 361-363, 2015 | 25 | 2015 |
Altered discharges of spinal neurons parallel the behavioral phenotype shown by rats with bortezomib related chemotherapy induced peripheral neuropathy CR Robinson, H Zhang, PM Dougherty Brain research 1574, 6-13, 2014 | 23 | 2014 |
Subclinical pretreatment sensory deficits appear to predict the development of pain and numbness in patients with multiple myeloma undergoing chemotherapy EG Vichaya, XS Wang, JA Boyette-Davis, TR Mendoza, Z He, SK Thomas, ... Cancer chemotherapy and pharmacology 71, 1531-1540, 2013 | 23 | 2013 |
Spinal injection of IL-2 or IL-15 alters mechanical and thermal withdrawal thresholds in rats JP Cata, HR Weng, PM Dougherty Neuroscience letters 437 (1), 45-49, 2008 | 23 | 2008 |
Response properties of dorsal root reflexes in cutaneous C fibers before and after intradermal capsaicin injection in rats HR Weng, PM Dougherty Neuroscience 132 (3), 823-831, 2005 | 23 | 2005 |