A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging M Mohrin, J Shin, Y Liu, K Brown, H Luo, Y Xi, CM Haynes, D Chen Science 347 (6228), 1374-1377, 2015 | 474 | 2015 |
SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease J Shin, M He, Y Liu, S Paredes, L Villanova, K Brown, X Qiu, N Nabavi, ... Cell reports 5 (3), 654-665, 2013 | 281 | 2013 |
Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells C Hom, J Lu, M Liong, H Luo, Z Li, JI Zink, F Tamanoi Small (Weinheim an der Bergstrasse, Germany) 6 (11), 1185, 2010 | 281 | 2010 |
An acetylation switch of the NLRP3 inflammasome regulates aging-associated chronic inflammation and insulin resistance M He, HH Chiang, H Luo, Z Zheng, Q Qiao, L Wang, M Tan, R Ohkubo, ... Cell metabolism 31 (3), 580-591. e5, 2020 | 263 | 2020 |
m6A RNA methylation maintains hematopoietic stem cell identity and symmetric commitment Y Cheng, H Luo, F Izzo, BF Pickering, D Nguyen, R Myers, A Schurer, ... Cell reports 28 (7), 1703-1716. e6, 2019 | 144 | 2019 |
N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation Y Cheng, W Xie, BF Pickering, KL Chu, AM Savino, X Yang, H Luo, ... Cancer cell 39 (7), 958-972. e8, 2021 | 133 | 2021 |
SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells Y Wang, FS Yen, XG Zhu, RC Timson, R Weber, C Xing, Y Liu, B Allwein, ... Nature 599 (7883), 136-140, 2021 | 122 | 2021 |
Mitochondrial stress-initiated aberrant activation of the NLRP3 inflammasome regulates the functional deterioration of hematopoietic stem cell aging H Luo, WC Mu, R Karki, HH Chiang, M Mohrin, JJ Shin, R Ohkubo, K Ito, ... Cell reports 26 (4), 945-954. e4, 2019 | 121 | 2019 |
Nutrient sensing and the oxidative stress response H Luo, HH Chiang, M Louw, A Susanto, D Chen Trends in Endocrinology & Metabolism 28 (6), 449-460, 2017 | 101 | 2017 |
The mitochondrial unfolded protein response is activated upon hematopoietic stem cell exit from quiescence M Mohrin, A Widjaja, Y Liu, H Luo, D Chen Aging Cell 17 (3), e12756, 2018 | 59 | 2018 |
Acute myeloid leukemia iPSCs reveal a role for RUNX1 in the maintenance of human leukemia stem cells J Wesely, AG Kotini, F Izzo, H Luo, H Yuan, J Sun, M Georgomanoli, ... Cell reports 31 (9), 2020 | 36 | 2020 |
Inhalative formaldehyde exposure enhances aggressive behavior and disturbs monoamines in frontal cortex synaptosome of male rats Y Liu, Z Ye, H Luo, M Sun, M Li, D Fan, D Chui Neuroscience Letters 464 (2), 113-116, 2009 | 27 | 2009 |
Rapid interrogation of cancer cell of origin through CRISPR editing W Feng, Z Cao, PX Lim, H Zhao, H Luo, N Mao, YS Lee, AA Rivera, ... Proceedings of the National Academy of Sciences 118 (32), e2110344118, 2021 | 17 | 2021 |
A TCR mimic CAR T cell specific for NDC80 is broadly reactive with solid tumors and hematologic malignancies MG Klatt, T Dao, Z Yang, J Liu, SS Mun, MM Dacek, H Luo, TJ Gardner, ... Blood, The Journal of the American Society of Hematology 140 (8), 861-874, 2022 | 10 | 2022 |
γ-Tocotrienol–Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs S Lee, TM Kalidindi, H Lou, K Gangangari, B Punzalan, A Bitton, CJ Lee, ... Journal of Nuclear Medicine 62 (4), 584-590, 2021 | 7 | 2021 |
Rubbing out leukemia stem cells by erasing the eraser Y Cheng, H Luo, MG Kharas Cell stem cell 27 (1), 3-5, 2020 | 7 | 2020 |
Patient-derived iPSCs faithfully represent the genetic diversity and cellular architecture of human acute myeloid leukemia AG Kotini, S Carcamo, N Cruz-Rodriguez, M Olszewska, T Wang, ... Blood cancer discovery 4 (4), 318-335, 2023 | 6 | 2023 |
A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML T Dao, G Xiong, SS Mun, J Meyerberg, T Korontsvit, J Xiang, Z Cui, ... Blood 143 (6), 507-521, 2024 | 4 | 2024 |
SON is an essential m6A target for hematopoietic stem cell fate H Luo, M Cortés-López, CL Tam, M Xiao, I Wakiro, KL Chu, A Pierson, ... Cell Stem Cell 30 (12), 1658-1673. e10, 2023 | 4 | 2023 |
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells F Herrejon Chavez, H Luo, P Cifani, A Pine, KL Chu, S Joshi, E Barin, ... Nature Communications 14 (1), 2290, 2023 | 3 | 2023 |