Clostridia: the importance of their exceptional substrate and metabolite diversity for biofuel and biorefinery applications BP Tracy, SW Jones, AG Fast, DC Indurthi, ET Papoutsakis Current opinion in biotechnology 23 (3), 364-381, 2012 | 479 | 2012 |
Resolving the TCA cycle and pentose‐phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis SB Crown, DC Indurthi, WS Ahn, J Choi, ET Papoutsakis, MR Antoniewicz Biotechnology journal 6 (3), 300-305, 2011 | 109 | 2011 |
Synthetic tolerance: three noncoding small RNAs, DsrA, ArcZ and RprA, acting supra-additively against acid stress SM Gaida, MA Al-Hinai, DC Indurthi, SA Nicolaou, ET Papoutsakis Nucleic acids research 41 (18), 8726-8737, 2013 | 103 | 2013 |
Small RNAs in the Genus Clostridium Y Chen, DC Indurthi, SW Jones, ET Papoutsakis MBio 2 (1), 10.1128/mbio. 00340-10, 2011 | 96 | 2011 |
A genomic-library based discovery of a novel, possibly synthetic, acid-tolerance mechanism in Clostridium acetobutylicum involving non-coding RNAs and ribosomal RNA processing JR Borden, SW Jones, D Indurthi, Y Chen, ET Papoutsakis Metabolic engineering 12 (3), 268-281, 2010 | 86 | 2010 |
Galantamine is not a positive allosteric modulator of human α4β2 or α7 nicotinic acetylcholine receptors NM Kowal, PK Ahring, VWY Liao, DC Indurti, BS Harvey, SM O'Connor, ... British journal of pharmacology 175 (14), 2911-2925, 2018 | 43 | 2018 |
Presence of multiple binding sites on α9α10 nAChR receptors alludes to stoichiometric-dependent action of the α-conotoxin, Vc1. 1 DC Indurthi, E Pera, HL Kim, C Chu, MD McLeod, JM McIntosh, ... Biochemical pharmacology 89 (1), 131-140, 2014 | 39 | 2014 |
Engineered α4β2 nicotinic acetylcholine receptors as models for measuring agonist binding and effect at the orthosteric low-affinity α4–α4 interface PK Ahring, JA Olsen, EØ Nielsen, D Peters, MHF Pedersen, LA Rohde, ... Neuropharmacology 92, 135-145, 2015 | 27 | 2015 |
CHRFAM7A: a human specific fusion gene, accounts for the translational gap for cholinergic strategies in Alzheimer's disease K Szigeti, I Ihnatovych, B Birkaya, Z Chen, A Ouf, DC Indurthi, JE Bard, ... EBioMedicine 59, 2020 | 24 | 2020 |
Gain-of-function GABRB3 variants identified in vigabatrin-hypersensitive epileptic encephalopathies NL Absalom, VWY Liao, K Kothur, DC Indurthi, B Bennetts, C Troedson, ... Brain communications 2 (2), fcaa162, 2020 | 22 | 2020 |
Pinnatoxins E, F and G target multiple nicotinic receptor subtypes SD Hellyer, D Indurthi, T Balle, V Runder‐Varga, AI Selwood, JDA Tyndall, ... Journal of Neurochemistry 135 (3), 479-491, 2015 | 19 | 2015 |
Lower tubulin expression in glioblastoma stem cells attenuates efficacy of microtubule-targeting agents RH Abbassi, A Recasens, DC Indurthi, TG Johns, BW Stringer, BW Day, ... ACS Pharmacology & Translational Science 2 (6), 402-413, 2019 | 18 | 2019 |
Recombinant clostridia that fix CO2 and CO and uses thereof ET Papoutsakis, MA Al-Hinai, SW Jones, DC Indurthi, DK Mitchell, A Fast US Patent 8,759,070, 2014 | 16 | 2014 |
Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry DC Indurthi, T Qudah, VW Liao, PK Ahring, TM Lewis, T Balle, M Chebib, ... Pharmacological Research 139, 215-227, 2019 | 12 | 2019 |
Ligand binding at the α4-α4 agonist-binding site of the α4β2 nAChR triggers receptor activation through a pre-activated conformational state DC Indurthi, TM Lewis, PK Ahring, T Balle, M Chebib, NL Absalom PLoS One 11 (8), e0161154, 2016 | 12 | 2016 |
Novel approach for the search for chemical scaffolds with activity at both acetylcholinesterase and the α7 nicotinic acetylcholine receptor: a perspective on scaffolds with … NM Kowal, DC Indurthi, PK Ahring, M Chebib, ES Olafsdottir, T Balle Molecules 24 (3), 446, 2019 | 10 | 2019 |
Agonist efficiency estimated from concentration response curve D Indurthi, A Auerbach Biophysical Journal 120 (3), 57a, 2021 | 9* | 2021 |
Tying up nicotine: new selective competitive antagonist of the neuronal nicotinic acetylcholine receptors IN Petersen, F Crestey, AA Jensen, DC Indurthi, H Pedersen, ... ACS Medicinal Chemistry Letters 6 (4), 472-475, 2015 | 6 | 2015 |
Agonist efficiency links binding and gating in a nicotinic receptor DC Indurthi, A Auerbach Elife 12, e86496, 2023 | 4 | 2023 |
AE Succinimide, an Analogue of Methyllycaconitine, When Bound Generates a Nonconducting Conformation of the α4β2 Nicotinic Acetylcholine Receptor T Qudah, GX Quek, D Indurthi, N Karim, JI Halliday, N Absalom, ... ACS Chemical Neuroscience 11 (3), 344-355, 2020 | 3 | 2020 |