Reprogramming human T cell function and specificity with non-viral genome targeting TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ... Nature 559 (7714), 405-409, 2018 | 786 | 2018 |
Genome-wide CRISPR screens in primary human T cells reveal key regulators of immune function E Shifrut, J Carnevale, V Tobin, TL Roth, JM Woo, CT Bui, PJ Li, ... Cell 175 (7), 1958-1971. e15, 2018 | 459 | 2018 |
Discovery of stimulation-responsive immune enhancers with CRISPR activation DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ... Nature 549 (7670), 111-115, 2017 | 292 | 2017 |
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ... Nature biotechnology 38 (1), 44-49, 2020 | 237 | 2020 |
A functional map of HIV-host interactions in primary human T cells J Hiatt, JF Hultquist, MJ McGregor, M Bouhaddou, RT Leenay, LM Simons, ... Nature communications 13 (1), 1752, 2022 | 37 | 2022 |
Runx1 and Runx3 drive progenitor to T-lineage transcriptome conversion in mouse T cell commitment via dynamic genomic site switching B Shin, H Hosokawa, M Romero-Wolf, W Zhou, K Masuhara, VR Tobin, ... Proceedings of the National Academy of Sciences 118 (4), e2019655118, 2021 | 37 | 2021 |
Engineering RNA export for measurement and manipulation of living cells F Horns, JA Martinez, C Fan, M Haque, JM Linton, V Tobin, L Santat, ... Cell 186 (17), 3642-3658. e32, 2023 | 28 | 2023 |
Synthetic protein circuits for programmable control of mammalian cell death S Xia, AC Lu, V Tobin, K Luo, L Moeller, DJ Shon, R Du, JM Linton, M Sui, ... Cell 187 (11), 2785-2800. e16, 2024 | | 2024 |
B7-h3-specific engager T cells for the immunotherapy of pediatric solid tumors C DeRenzo, D Torres, V Tobin, P Nguyen, S Xiao-Tong, S Gottschalk Journal for ImmunoTherapy of Cancer 3 (Suppl 2), 2015 | | 2015 |