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Anurag Khetan
Anurag Khetan
Executive Director, Biologics Development, Bristol-Myers Squibb
在 khetans.com 的电子邮件经过验证
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Cell culture media for recombinant protein expression in Chinese hamster ovary (CHO) cells: History, key components, and optimization strategies
FV Ritacco, Y Wu, A Khetan
Biotechnology progress 34 (6), 1407-1426, 2018
2722018
Control of misincorporation of serine for asparagine during antibody production using CHO cells
A Khetan, Y Huang, J Dolnikova, NE Pederson, D Wen, ...
Biotechnology and bioengineering 107 (1), 116-123, 2010
722010
Method of supplementing culture media to prevent undesirable amino acid substitutions
A Khetan, YM Huang, J Dolnikova, N Pederson, H Yusuf-Makagiansar, ...
US Patent 9,096,879, 2015
482015
Precursor and Cofactor as a Check Valve for Cephamycin Biosynthesis in Streptomycesclavuligerus
A Khetan, LH Malmberg, YS Kyung, DH Sherman, WS Hu
Biotechnology progress 15 (6), 1020-1027, 1999
241999
Advancement in bioprocess technology: parallels between microbial natural products and cell culture biologics
AA Bandyopadhyay, A Khetan, LH Malmberg, W Zhou, WS Hu
Journal of Industrial Microbiology and Biotechnology 44 (4-5), 785-797, 2017
202017
Enabling speed to clinic for monoclonal antibody programs using a pool of clones for IND-enabling toxicity studies
P Bolisetty, G Tremml, S Xu, A Khetan
MAbs 12 (1), 1763727, 2020
182020
Gradient elution behavior of proteins in hydrophobic interaction chromatography with U-shaped retention factor curves
A Creasy, J Lomino, G Barker, A Khetan, G Carta
Journal of Chromatography A 1547, 53-61, 2018
182018
Metabolic engineering of cephalosporin biosynthesis in Streptomyces clavuligerus.
A Khetan, LH Malmberg, DH Sherman, WS Hu
Annals of the New York Academy of Sciences 782, 17-24, 1996
181996
Heterogeneous distribution of lysine 6-aminotransferase during cephamycin C biosynthesis in Streptomyces clavuligerus demonstrated using green fluorescent …
A Khetan, WS Hu, DH Sherman
Microbiology 146 (8), 1869-1880, 2000
172000
N-1 perfusion platform development using a capacitance probe for biomanufacturing
ESC Rittershaus, MS Rehmann, J Xu, Q He, C Hill, J Swanberg, ...
Bioengineering 9 (4), 128, 2022
162022
Understanding the effect of high gas entrance velocity on Chinese hamster ovary (CHO) cell culture performance and its implications on bioreactor scale‐up and sparger design
G Chaudhary, R Luo, M George, L Tescione, A Khetan, H Lin
Biotechnology and Bioengineering 117 (6), 1684-1695, 2020
162020
Upstream cell culture process characterization and in-process control strategy development at pandemic speed
J Xu, J Ou, KP McHugh, MC Borys, A Khetan
MAbs 14 (1), 2060724, 2022
142022
Time‐lapsed confocal microscopy reveals temporal and spatial expression of the lysine ɛ‐aminotransferase gene in Streptomyces clavuligerus
L Han, A Khetan, WS Hu, DH Sherman
Molecular Microbiology 34 (5), 878-886, 1999
131999
Applications of small molecules in modulating productivity and product quality of recombinant proteins produced using cell cultures
P Xu, S Xu, C He, A Khetan
Biotechnology Advances 43, 107577, 2020
122020
Process modeling of recombinant adeno-associated virus production in HEK293 cells
J Joiner, Z Huang, K McHugh, M Stebbins, K Aron, M Borys, A Khetan
Current Opinion in Chemical Engineering 36, 100823, 2022
112022
Metabolic engineering of antibiotic biosynthetic pathways
A Khetan
Manual of industrial microbiology and biotechnology, 717-724, 1999
101999
New insights into genetic instability of an industrial CHO cell line by orthogonal omics
Y Qian, SW Sowa, KL Aron, P Xu, E Langsdorf, B Warrack, N Aranibar, ...
Biochemical Engineering Journal 164, 107799, 2020
92020
Suitability of a generic virus safety evaluation for monoclonal antibody investigational new drug applications
P Sipple, T Nguyen, K Patel, N Jaffe, Y Chen, A Khetan
Biotechnology Progress 35 (5), e2850, 2019
92019
Metabolic engineering of antibiotic biosynthesis for process improvement
A Khetan, WS Hu
Bioprocess technology 24, 177-202, 1997
81997
Recent advances in upstream process development for production of recombinant adeno‐associated virus
J Ou, Y Tang, J Xu, J Tucci, MC Borys, A Khetan
Biotechnology and Bioengineering 121 (1), 53-70, 2024
62024
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