| Delivering the messenger: advances in technologies for therapeutic mRNA delivery PS Kowalski, A Rudra, L Miao, DG Anderson Molecular Therapy 27 (4), 710-728, 2019 | 868 | 2019 |
| Advances in the delivery of RNA therapeutics: from concept to clinical reality JC Kaczmarek, PS Kowalski, DG Anderson Genome medicine 9, 1-16, 2017 | 655 | 2017 |
| Engineering circular RNA for potent and stable translation in eukaryotic cells RA Wesselhoeft, PS Kowalski, DG Anderson Nature communications 9 (1), 2629, 2018 | 466 | 2018 |
| RNA circularization diminishes immunogenicity and can extend translation duration in vivo RA Wesselhoeft, PS Kowalski, FC Parker-Hale, Y Huang, N Bisaria, ... Molecular cell 74 (3), 508-520. e4, 2019 | 281 | 2019 |
| Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo KJ Kauffman, FF Mir, S Jhunjhunwala, JC Kaczmarek, JE Hurtado, ... Biomaterials 109, 78-87, 2016 | 184 | 2016 |
| Smart biomaterials: recent advances and future directions PS Kowalski, C Bhattacharya, S Afewerki, R Langer ACS biomaterials science & engineering 4 (11), 3809-3817, 2018 | 169 | 2018 |
| mRNA delivery for therapeutic anti-HER2 antibody expression in vivo Y Rybakova, PS Kowalski, Y Huang, JT Gonzalez, MW Heartlein, ... Molecular Therapy 27 (8), 1415-1423, 2019 | 152 | 2019 |
| Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy K Jung, T Heishi, OF Khan, PS Kowalski, J Incio, NN Rahbari, E Chung, ... The Journal of clinical investigation 127 (8), 3039-3051, 2017 | 150 | 2017 |
| Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations S Farah, JC Doloff, P Müller, A Sadraei, HJ Han, K Olafson, K Vyas, ... Nature materials 18 (8), 892-904, 2019 | 148 | 2019 |
| Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone R Reshke, JA Taylor, A Savard, H Guo, LH Rhym, PS Kowalski, MT Trung, ... Nature biomedical engineering 4 (1), 52-68, 2020 | 122 | 2020 |
| Ionizable amino‐polyesters synthesized via ring opening polymerization of tertiary amino‐alcohols for tissue selective mRNA delivery PS Kowalski, U Capasso Palmiero, Y Huang, A Rudra, R Langer, ... Advanced materials 30 (34), 1801151, 2018 | 110 | 2018 |
| Endothelial siRNA delivery in nonhuman primates using ionizable low–molecular weight polymeric nanoparticles OF Khan, PS Kowalski, JC Doloff, JK Tsosie, V Bakthavatchalu, CB Winn, ... Science advances 4 (6), eaar8409, 2018 | 97 | 2018 |
| Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche M Krohn-Grimberghe, MJ Mitchell, MJ Schloss, OF Khan, G Courties, ... Nature biomedical engineering 4 (11), 1076-1089, 2020 | 93 | 2020 |
| Anti-VCAM-1 SAINT-O-Somes enable endothelial-specific delivery of siRNA and downregulation of inflammatory genes in activated endothelium in vivo PS Kowalski, PJ Zwiers, HWM Morselt, JM Kuldo, NGJ Leus, MHJ Ruiters, ... Journal of controlled release 176, 64-75, 2014 | 79 | 2014 |
| Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β–induced Serpine1 JV McCann, L Xiao, DJ Kim, OF Khan, PS Kowalski, DG Anderson, ... The Journal of clinical investigation 129 (4), 1654-1670, 2019 | 78 | 2019 |
| Anti-VCAM-1 and anti-E-selectin SAINT-O-Somes for selective delivery of siRNA into inflammation-activated primary endothelial cells PS Kowalski, LL Lintermans, HWM Morselt, NGJ Leus, MHJ Ruiters, ... Molecular pharmaceutics 10 (8), 3033-3044, 2013 | 72 | 2013 |
| Heparin enhances serpin inhibition of the cysteine protease cathepsin L WJ Higgins, DM Fox, PS Kowalski, JE Nielsen, DM Worrall Journal of biological chemistry 285 (6), 3722-3729, 2010 | 64 | 2010 |
| A critical role for Egr-1 during vascular remodelling in pulmonary arterial hypertension MG Dickinson, PS Kowalski, B Bartelds, MAJ Borgdorff, D van der Feen, ... Cardiovascular research 103 (4), 573-584, 2014 | 46 | 2014 |
| Targeted siRNA delivery to diseased microvascular endothelial cells—Cellular and molecular concepts PS Kowalski, NGJ Leus, GL Scherphof, MHJ Ruiters, JAAM Kamps, ... IUBMB life 63 (8), 648-658, 2011 | 42 | 2011 |
| Effective siRNA delivery to inflamed primary vascular endothelial cells by anti-E-selectin and anti-VCAM-1 PEGylated SAINT-based lipoplexes NGJ Leus, EG Talman, P Ramana, PS Kowalski, ... International journal of pharmaceutics 459 (1-2), 40-50, 2014 | 37 | 2014 |
Daniel G. AndersonMassachusetts Institute of Technology在 mit.edu 的电子邮件经过验证
