关注
Piotr S. Kowalski, PhD
Piotr S. Kowalski, PhD
Associate professor (Senior Lecturer), School of Pharmacy, University College Cork
在 ucc.ie 的电子邮件经过验证
标题
引用次数
引用次数
年份
Delivering the messenger: advances in technologies for therapeutic mRNA delivery
PS Kowalski, A Rudra, L Miao, DG Anderson
Molecular Therapy 27 (4), 710-728, 2019
8682019
Advances in the delivery of RNA therapeutics: from concept to clinical reality
JC Kaczmarek, PS Kowalski, DG Anderson
Genome medicine 9, 1-16, 2017
6552017
Engineering circular RNA for potent and stable translation in eukaryotic cells
RA Wesselhoeft, PS Kowalski, DG Anderson
Nature communications 9 (1), 2629, 2018
4662018
RNA circularization diminishes immunogenicity and can extend translation duration in vivo
RA Wesselhoeft, PS Kowalski, FC Parker-Hale, Y Huang, N Bisaria, ...
Molecular cell 74 (3), 508-520. e4, 2019
2812019
Efficacy and immunogenicity of unmodified and pseudouridine-modified mRNA delivered systemically with lipid nanoparticles in vivo
KJ Kauffman, FF Mir, S Jhunjhunwala, JC Kaczmarek, JE Hurtado, ...
Biomaterials 109, 78-87, 2016
1842016
Smart biomaterials: recent advances and future directions
PS Kowalski, C Bhattacharya, S Afewerki, R Langer
ACS biomaterials science & engineering 4 (11), 3809-3817, 2018
1692018
mRNA delivery for therapeutic anti-HER2 antibody expression in vivo
Y Rybakova, PS Kowalski, Y Huang, JT Gonzalez, MW Heartlein, ...
Molecular Therapy 27 (8), 1415-1423, 2019
1522019
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy
K Jung, T Heishi, OF Khan, PS Kowalski, J Incio, NN Rahbari, E Chung, ...
The Journal of clinical investigation 127 (8), 3039-3051, 2017
1502017
Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations
S Farah, JC Doloff, P Müller, A Sadraei, HJ Han, K Olafson, K Vyas, ...
Nature materials 18 (8), 892-904, 2019
1482019
Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone
R Reshke, JA Taylor, A Savard, H Guo, LH Rhym, PS Kowalski, MT Trung, ...
Nature biomedical engineering 4 (1), 52-68, 2020
1222020
Ionizable amino‐polyesters synthesized via ring opening polymerization of tertiary amino‐alcohols for tissue selective mRNA delivery
PS Kowalski, U Capasso Palmiero, Y Huang, A Rudra, R Langer, ...
Advanced materials 30 (34), 1801151, 2018
1102018
Endothelial siRNA delivery in nonhuman primates using ionizable low–molecular weight polymeric nanoparticles
OF Khan, PS Kowalski, JC Doloff, JK Tsosie, V Bakthavatchalu, CB Winn, ...
Science advances 4 (6), eaar8409, 2018
972018
Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche
M Krohn-Grimberghe, MJ Mitchell, MJ Schloss, OF Khan, G Courties, ...
Nature biomedical engineering 4 (11), 1076-1089, 2020
932020
Anti-VCAM-1 SAINT-O-Somes enable endothelial-specific delivery of siRNA and downregulation of inflammatory genes in activated endothelium in vivo
PS Kowalski, PJ Zwiers, HWM Morselt, JM Kuldo, NGJ Leus, MHJ Ruiters, ...
Journal of controlled release 176, 64-75, 2014
792014
Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β–induced Serpine1
JV McCann, L Xiao, DJ Kim, OF Khan, PS Kowalski, DG Anderson, ...
The Journal of clinical investigation 129 (4), 1654-1670, 2019
782019
Anti-VCAM-1 and anti-E-selectin SAINT-O-Somes for selective delivery of siRNA into inflammation-activated primary endothelial cells
PS Kowalski, LL Lintermans, HWM Morselt, NGJ Leus, MHJ Ruiters, ...
Molecular pharmaceutics 10 (8), 3033-3044, 2013
722013
Heparin enhances serpin inhibition of the cysteine protease cathepsin L
WJ Higgins, DM Fox, PS Kowalski, JE Nielsen, DM Worrall
Journal of biological chemistry 285 (6), 3722-3729, 2010
642010
A critical role for Egr-1 during vascular remodelling in pulmonary arterial hypertension
MG Dickinson, PS Kowalski, B Bartelds, MAJ Borgdorff, D van der Feen, ...
Cardiovascular research 103 (4), 573-584, 2014
462014
Targeted siRNA delivery to diseased microvascular endothelial cells—Cellular and molecular concepts
PS Kowalski, NGJ Leus, GL Scherphof, MHJ Ruiters, JAAM Kamps, ...
IUBMB life 63 (8), 648-658, 2011
422011
Effective siRNA delivery to inflamed primary vascular endothelial cells by anti-E-selectin and anti-VCAM-1 PEGylated SAINT-based lipoplexes
NGJ Leus, EG Talman, P Ramana, PS Kowalski, ...
International journal of pharmaceutics 459 (1-2), 40-50, 2014
372014
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