De novo protein design enables the precise induction of RSV-neutralizing antibodies F Sesterhenn, C Yang, J Bonet, JT Cramer, X Wen, Y Wang, CI Chiang, ... Science 368 (6492), eaay5051, 2020 | 165 | 2020 |
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers E Rujas, I Kucharska, YZ Tan, S Benlekbir, H Cui, T Zhao, GA Wasney, ... Nature Communications 12 (1), 3661, 2021 | 66* | 2021 |
Refinement of OprH-LPS interactions by molecular simulations J Lee, DS Patel, I Kucharska, LK Tamm, W Im Biophysical journal 112 (2), 346-355, 2017 | 54 | 2017 |
Optimizing nanodiscs and bicelles for solution NMR studies of two β-barrel membrane proteins I Kucharska, TC Edrington, B Liang, LK Tamm Journal of biomolecular NMR 61, 261-274, 2015 | 44 | 2015 |
Recognition of semaphorin proteins by P. sordellii lethal toxin reveals principles of receptor specificity in clostridial toxins H Lee, GL Beilhartz, I Kucharska, S Raman, H Cui, MHY Lam, H Liang, ... Cell 182 (2), 345-356. e16, 2020 | 38 | 2020 |
Biochemical reconstitution of HIV-1 assembly and maturation I Kucharska, P Ding, KK Zadrozny, RA Dick, MF Summers, ... Journal of virology 94 (5), 10.1128/jvi. 01844-19, 2020 | 36 | 2020 |
Molecular Interactions of Lipopolysaccharide with an Outer Membrane Protein from Pseudomonas aeruginosa Probed by Solution NMR I Kucharska, B Liang, N Ursini, LK Tamm Biochemistry 55 (36), 5061-5072, 2016 | 35 | 2016 |
Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses B McLeod, MT Mabrouk, K Miura, R Ravichandran, S Kephart, ... Immunity 55 (9), 1680-1692. e8, 2022 | 33 | 2022 |
OprG harnesses the dynamics of its extracellular loops to transport small amino acids across the outer membrane of Pseudomonas aeruginosa I Kucharska, P Seelheim, T Edrington, B Liang, LK Tamm Structure 23 (12), 2234-2245, 2015 | 31 | 2015 |
Inactivation of MS2 bacteriophage and adenovirus with silver and copper in solution and embedded in ceramic water filters KN Jackson, DM Kahler, I Kucharska, D Rekosh, ML Hammarskjold, ... Journal of Environmental Engineering 146 (3), 04019130, 2020 | 27 | 2020 |
A molecular switch modulates assembly and host factor binding of the HIV-1 capsid RT Schirra, NFB Dos Santos, KK Zadrozny, I Kucharska, ... Nature structural & molecular biology 30 (3), 383-390, 2023 | 20 | 2023 |
Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11 I Kucharska, E Thai, A Srivastava, JL Rubinstein, R Pomès, JP Julien Elife 9, e59018, 2020 | 20 | 2020 |
Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22 J Ereño-Orbea, X Liu, T Sicard, I Kucharska, W Li, D Borovsky, H Cui, ... Journal of Biological Chemistry 297 (2), 2021 | 11 | 2021 |
Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats I Kucharska, L Hossain, D Ivanochko, Q Yang, JL Rubinstein, R Pomès, ... Elife 11, e72908, 2022 | 10 | 2022 |
Protein rethreading: A novel approach to protein design S Agah, S Poulos, A Yu, I Kucharska, S Faham Scientific reports 6 (1), 26847, 2016 | 8 | 2016 |
A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo C Burn Aschner, K Muthuraman, I Kucharska, H Cui, K Prieto, MS Nair, ... Science Translational Medicine 15 (697), eadf4549, 2023 | 7 | 2023 |
Solution NMR provides new insight into lipid–protein interaction I Kucharska, LK Tamm Biochemistry 56 (33), 4291-4292, 2017 | 7 | 2017 |
High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire I Kucharska, Š Binter, R Murugan, SW Scally, J Ludwig, K Prieto, E Thai, ... PLoS pathogens 18 (11), e1010999, 2022 | 6 | 2022 |
Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses A Kassardjian, E Sun, J Sookhoo, K Muthuraman, KF Boligan, ... Cell Reports 42 (4), 2023 | 2 | 2023 |
Connexin Gap Junction Channels and Hemichannels: Insights from High-Resolution Structures M Jagielnicki, I Kucharska, BC Bennett, AL Harris, M Yeager Biology 13 (5), 298, 2024 | 1 | 2024 |